15 research outputs found
Kitai-Gorod : Roman aus dem Moskauer Kaufmannsleben / von Peter Boborykin ; aus dem Russischen von Erwin Bauer
ΠΡΠΈΡ ΠΎΠΌΠΎΡΠΎΡΠ½ΡΠ΅ Π½Π°ΡΡΡΠ΅Π½ΠΈΡ Ρ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΡ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ ΠΏΡΠΈ ΠΎΠΏΠΈΡΡΠΎΡΡ ΠΎΠ·Π΅
The purpose of the research is to study adaptative and neurological onsets in the behavior of animals infected by Opisthorchis felineus. Materials and methods. The research was conducted on 10 buck rabbits orally infected by metacercariae O. felineus in a dose of 50 specimen per one animal. 9 health breeding stock animals were the control. Infection was confirmed by laboratory research of feces after 1.5 months with the detection of trematode ootids. The research of psychomotor reactions β somatosensorial, visile (photic), sound with evaluation of general animal reaction, their behavior and response of organs of senses was conducted after 4 months.Results and discussion. Aggressively-destructive disorders were established in the primary reaction to contact, in which the two-phase behavior is established, a short phase of aggression, alternating with a long inhibitory phase. Anxiety state showing in disorientation of movements, head turning in combination with the reaction of exclusion has been established in infected animals. Disorientation, active motor behavior similar to attack (aggression), ears pressing was noted when applying photic stimuli. Absence of forced squeezing, the reaction of the third eyelid was observed when taking into account reactions of eye assist device on photic stimulus. Absence of suspension reaction, anxiety was established under exposer of sound stimuli in animals, presence of loginess and absence of the reaction. Thus, psychomotor disorders apparently associated with toxic hepatic encephalopathy and general subcompensated dysfunction of the nervous system was noted in the cases of opisthorchosis after 4 months.Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ: ΠΈΠ·ΡΡΠΈΡΡ Π°Π΄Π°ΠΏΡΠ°ΡΠΈΠΎΠ½Π½ΠΎ-Π½Π΅Π²ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΡΠΎΡΠ²Π»Π΅Π½ΠΈΡ Π² ΠΏΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠΈ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
, Π·Π°ΡΠ°ΠΆΠ΅Π½Π½ΡΡ
Opisthochisfelineus.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ Π½Π° 10 ΠΊΡΠΎΠ»ΠΈΠΊΠ°Ρ
-ΡΠ°ΠΌΡΠ°Ρ
, ΠΈΠ½Π²Π°Π·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΏΠ΅ΡΠΎΡΠ°Π»ΡΠ½ΠΎ ΠΌΠ΅ΡΠ°ΡΠ΅ΡΠΊΠ°ΡΠΈΡΠΌΠΈ O. felineus Π² Π΄ΠΎΠ·Π΅ ΠΏΠΎ 50 ΡΠΊΠ·. Π½Π° ΠΎΠ΄Π½Ρ ΠΎΡΠΎΠ±Ρ. ΠΠΎΠ½ΡΡΠΎΠ»Ρ ΡΠΎΡΡΠ°Π²ΠΈΠ»ΠΈ 9 Π·Π΄ΠΎΡΠΎΠ²ΡΡ
ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
ΠΌΠ°ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ³ΠΎΠ»ΠΎΠ²ΡΡ. ΠΠ°ΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΡ ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠΆΠ΄Π°Π»ΠΈ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΡΠΌΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ΅ΠΊΠ°Π»ΠΈΠΉ ΡΠ΅ΡΠ΅Π· 1,5 ΠΌΠ΅Ρ. Ρ ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½ΠΈΠ΅ΠΌ ΡΠΈΡ ΡΡΠ΅ΠΌΠ°ΡΠΎΠ΄. Π§Π΅ΡΠ΅Π· 4 ΠΌΠ΅Ρ. ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠΈΡ
ΠΎΠΌΠΎΡΠΎΡΠ½ΡΡ
ΡΠ΅Π°ΠΊΡΠΈΠΉ β ΡΠΎΠΌΠ°ΡΠΎΡΠ΅Π½ΡΠΎΡΠ½ΡΠ΅, Π·ΡΠΈΡΠ΅Π»ΡΠ½ΡΠ΅ (ΡΠ²Π΅ΡΠΎΠ²ΡΠ΅), Π·Π²ΡΠΊΠΎΠ²ΡΠ΅ Ρ ΠΎΡΠ΅Π½ΠΊΠΎΠΉ ΠΎΠ±ΡΠ΅ΠΉ ΡΠ΅Π°ΠΊΡΠΈΠΈ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
, ΠΈΡ
ΠΏΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ ΠΈ ΠΎΡΠ²Π΅ΡΠ½ΠΎΠΉ ΡΠ΅Π°ΠΊΡΠΈΠΈ ΠΎΡΠ³Π°Π½ΠΎΠ² ΡΡΠ²ΡΡΠ².Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½Ρ Π°Π³ΡΠ΅ΡΡΠΈΠ²Π½ΠΎ-Π΄Π΅ΡΡΡΡΠΊΡΠΈΠ²Π½ΡΠ΅ ΡΠ°ΡΡΡΡΠΎΠΉΡΡΠ²Π° ΠΏΡΠΈ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎΠΉ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π½Π° ΠΊΠΎΠ½ΡΠ°ΠΊΡ, Π² ΠΊΠΎΡΠΎΡΠΎΠΉ ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½Π° Π΄Π²ΡΡ
ΡΠ°Π·Π½ΠΎΡΡΡ ΠΏΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ, ΠΊΠΎΡΠΎΡΠΊΠ°Ρ ΡΠ°Π·Π° Π°Π³ΡΠ΅ΡΡΠΈΠΈ, ΡΠ΅ΡΠ΅Π΄ΡΡΡΠ°ΡΡΡ Ρ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠ°Π·ΠΎΠΉ ΡΠΎΡΠΌΠΎΠΆΠ΅Π½ΠΈΡ. Π£ Π·Π°ΡΠ°ΠΆΠ΅Π½Π½ΡΡ
ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΠ΅ Π±Π΅ΡΠΏΠΎΠΊΠΎΠΉΡΡΠ²Π°, ΠΏΡΠΎΡΠ²Π»ΡΠ΅ΠΌΠΎΠ΅ Π² Π΄Π΅Π·ΠΎΡΠΈΠ΅Π½ΡΠ°ΡΠΈΠΈ Π΄Π²ΠΈΠΆΠ΅Π½ΠΈΠΉ, Π²ΡΠ°ΡΠ΅Π½ΠΈΠΈ Π³ΠΎΠ»ΠΎΠ²ΠΎΠΉ Π² ΡΠΎΡΠ΅ΡΠ°Π½ΠΈΠΈ Ρ ΡΠ΅Π°ΠΊΡΠΈΠ΅ΠΉ ΠΎΡΡΡΡΠ°Π½Π΅Π½ΠΈΡ. ΠΡΠΈ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠΈ ΡΠ²Π΅ΡΠΎΠ²ΡΡ
ΡΠ°Π·Π΄ΡΠ°ΠΆΠΈΡΠ΅Π»Π΅ΠΉ ΠΎΡΠΌΠ΅ΡΠ°Π»ΠΈ Π΄Π΅Π·ΠΎΡΠΈΠ΅Π½ΡΠ°ΡΠΈΡ, Π°ΠΊΡΠΈΠ²Π½ΠΎΠ΅ Π΄Π²ΠΈΠ³Π°ΡΠ΅Π»ΡΠ½ΠΎΠ΅ ΠΏΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅, Π½Π°ΠΏΠΎΠΌΠΈΠ½Π°ΡΡΠ΅Π΅ Π½Π°ΠΏΠ°Π΄Π΅Π½ΠΈΠ΅ (Π°Π³ΡΠ΅ΡΡΠΈΡ), ΠΏΡΠΈΠΆΠΈΠΌΠ°Π½ΠΈΠ΅ ΡΡΠ΅ΠΉ. ΠΡΠΈ ΡΡΠ΅ΡΠ΅ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π²ΡΠΏΠΎΠΌΠΎΠ³Π°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π°ΠΏΠΏΠ°ΡΠ°ΡΠ° Π³Π»Π°Π·Π° Π½Π° ΡΠ²Π΅ΡΠΎΠ²ΠΎΠΉ ΡΠ°Π·Π΄ΡΠ°ΠΆΠΈΡΠ΅Π»Ρ Π½Π°Π±Π»ΡΠ΄Π°Π»ΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΠ΅ ΡΠΎΡΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ Π·Π°ΠΆΠΌΡΡΠΈΠ²Π°Π½ΠΈΡ, ΡΠ΅Π°ΠΊΡΠΈΠΈ ΡΡΠ΅ΡΡΠ΅Π³ΠΎ Π²Π΅ΠΊΠ°. ΠΡΠΈ Π²ΠΎΠ·Π΄Π΅ΠΉΡΡΠ²ΠΈΠΈ Π·Π²ΡΠΊΠΎΠ²ΡΡ
ΡΠ°Π·Π΄ΡΠ°ΠΆΠΈΡΠ΅Π»Π΅ΠΉ Ρ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ ΠΎΡΡΡΡΡΡΠ²ΠΈΠ΅ ΡΠ΅Π°ΠΊΡΠΈΠΈ ΠΎΡΡΡΡΠ°Π½Π΅Π½ΠΈΡ, Π±Π΅ΡΠΏΠΎΠΊΠΎΠΉΡΡΠ²Π°, ΠΏΡΠΈΡΡΡΡΡΠ²ΠΎΠ²Π°Π»Π° Π·Π°ΡΠΎΡΠΌΠΎΠΆΠ΅Π½Π½ΠΎΡΡΡ ΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΠ΅ ΡΠ΅Π°ΠΊΡΠΈΠΈ. Π’Π°ΠΊΠΈΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠΌ, ΠΏΡΠΈ ΠΎΠΏΠΈΡΡΠΎΡΡ
ΠΎΠ·Π΅ ΡΠ΅ΡΠ΅Π· 4 ΠΌΠ΅Ρ. ΠΎΡΠΌΠ΅ΡΠ°Π»ΠΈ ΠΏΡΠΈΡ
ΠΎΠΌΠΎΡΠΎΡΠ½ΡΠ΅ Π½Π°ΡΡΡΠ΅Π½ΠΈΡ, ΡΠ²ΡΠ·Π°Π½Π½ΡΠ΅, ΠΏΠΎ-Π²ΠΈΠ΄ΠΈΠΌΠΎΠΌΡ, Ρ ΡΠΎΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠ΅ΡΠ΅Π½ΠΎΡΠ½ΠΎΠΉ ΡΠ½ΡΠ΅ΡΠ°Π»ΠΎΠΏΠ°ΡΠΈΠ΅ΠΉ ΠΈ ΠΎΠ±ΡΠ΅ΠΉ ΡΡΠ±ΠΊΠΎΠΌΠΏΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΠ΅ΠΉ Π½Π΅ΡΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ
ΠΠΠΠΠΠ§ΠΠ‘ΠΠΠ ΠΠ‘ΠΠΠΠ’Π« ΠΠ‘Π’Π ΠΠΠ ΠΠΠΠ‘Π’ΠΠ Π₯ΠΠΠ Π£ ΠΠ ΠΠΠΠΠΠ Π ΠΠΠ‘ΠΠΠ ΠΠΠΠΠ’Π
Objective of research: to investigate the clinical features of acute opisthorchiasis in rabbits.Materials and methods: Clinical evidence of acute opisthorchiasis in rabbits, laboratory blood tests.Results and discussion: Skin lesions in the form of cracks and ulcers of various sizes in the neck, thoracic back and croup, mostly localized along the spine, were clinically identified in acute opisthorchiasis of rabbits. Weight loss within the first month was up to 300 β500 grams. Laboratory tests showed that one month later, the level of blood glucose in the infected animals was 3 times higher than in controls. Compared with the controls, a reduced number of red blood cells and hemoglobin level in animals of the experimental group was observed, leukopenia was determined. The blood coagulation time was significantly accelerated.Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ β ΠΈΠ·ΡΡΠΈΡΡ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΠΏΡΠΎΡΠ΅ΠΊΠ°Π½ΠΈΡ ΠΎΡΡΡΠΎΠ³ΠΎ ΠΎΠΏΠΈΡΡΠΎΡΡ
ΠΎΠ·Π° Ρ ΠΊΡΠΎΠ»ΠΈΠΊΠΎΠ².ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π΄Π°Π½Π½ΡΠ΅ ΠΎΡΡΡΠΎΠ³ΠΎ ΠΎΠΏΠΈΡΡΠΎΡΡ
ΠΎΠ·Π° Ρ ΠΊΡΠΎΠ»ΠΈΠΊΠΎΠ², Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΡΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΊΡΠΎΠ²ΠΈ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅. ΠΡΠΈ ΠΎΡΡΡΠΎΠΌ ΠΎΠΏΠΈΡΡΠΎΡΡ
ΠΎΠ·Π΅ Ρ ΠΊΡΠΎΠ»ΠΈΠΊΠΎΠ² ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈ Π±ΡΠ»ΠΈ Π²ΡΠ΄Π΅Π»Π΅Π½Ρ ΠΊΠΎΠΆΠ½ΡΠ΅ ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΡ, ΠΏΡΠΎΡΠ²Π»ΡΠ²ΡΠΈΠ΅ΡΡ Π² Π²ΠΈΠ΄Π΅ ΡΡΠ΅ΡΠΈΠ½ ΠΈ ΡΠ·Π² ΡΠ°Π·Π½ΡΡ
ΡΠ°Π·ΠΌΠ΅ΡΠΎΠ², ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½Π½ΡΡ
Π² ΠΎΠ±Π»Π°ΡΡΠΈ Π·Π°ΡΡΠ»ΠΊΠ°, Π³ΡΡΠ΄Π½ΠΎΠΉ ΡΠ°ΡΡΠΈ ΡΠΏΠΈΠ½Ρ ΠΈ ΠΊΡΡΠΏΠ°, Π² ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠΌ, Π»ΠΎΠΊΠ°Π»ΠΈΠ·ΠΎΠ²Π°Π½Π½ΡΠ΅ Π²Π΄ΠΎΠ»Ρ ΠΏΠΎΠ·Π²ΠΎΠ½ΠΎΡΠ½ΠΈΠΊΠ°. ΠΠΎΡΠ΅ΡΡ Π²Π΅ΡΠ° ΡΠΎΡΡΠ°Π²ΠΈΠ»Π° Π·Π° ΠΏΠ΅ΡΠ²ΡΠΉ ΠΌΠ΅ΡΡΡ Π΄ΠΎ 300 β 500 Π³ΡΠ°ΠΌΠΌ. ΠΡΠΈ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΠΎΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ ΡΠ΅ΡΠ΅Π· ΠΎΠ΄ΠΈΠ½ ΠΌΠ΅ΡΡΡ Π² ΠΊΡΠΎΠ²ΠΈ Π·Π°ΡΠ°ΠΆΠ΅Π½Π½ΡΡ
ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
ΡΡΠΎΠ²Π΅Π½Ρ Π³Π»ΡΠΊΠΎΠ·Ρ ΠΏΡΠ΅Π²ΡΡΠ°Π» ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ Π² ΡΡΠΈ ΡΠ°Π·Π°. ΠΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ ΠΊΠΎΠ½ΡΡΠΎΠ»Π΅ΠΌ Ρ ΠΎΠΏΡΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ Π±ΡΠ»ΠΎ ΡΠ½ΠΈΠΆΠ΅Π½ΠΎ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΡΡΠΈΡΡΠΎΡΠΈΡΠΎΠ² ΠΈ Π³Π΅ΠΌΠΎΠ³Π»ΠΎΠ±ΠΈΠ½Π°, ΠΎΡΠΌΠ΅ΡΠ°Π»ΠΈ Π»Π΅ΠΉΠΊΠΎΠΏΠ΅Π½ΠΈΡ. Π‘ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎ ΡΡΠΊΠΎΡΡΠ»ΠΎΡΡ Π²ΡΠ΅ΠΌΡ ΡΠ²Π΅ΡΡΡΠ²Π°Π½ΠΈΡ ΠΊΡΠΎΠ²ΠΈ
ΠΠ΄Π°ΠΏΡΠ°ΡΠΈΡ Π²Π·Π°ΠΈΠΌΠΎΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠΉ Π² ΡΠΈΡΡΠ΅ΠΌΠ΅ Β«ΠΏΠ°ΡΠ°Π·ΠΈΡβΡ ΠΎΠ·ΡΠΈΠ½Β» ΠΏΡΠΈ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ Paramphistomum cervi Π² ΡΠΎΠ½ΠΊΠΎΠΌ ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ΅ ΠΎΠ²Π΅Ρ
The purpose of the research is studying microstructural changes in the process of adaptation of components during the formation of the βparasiteβhostβ system by the example of Paramphistomum cervi (Zeder, 1790) parasitizing in the small intestine of spontaneously infected sheep.Materials and methods. Peculiarities of changes in the microstructure of the small intestine in the βparasiteβhostβ system were studied using parasitization of P. cervi in the intestines of sheep using well-known histological methods. Pieces of tissue of the small intestine of sheep with P. cervi, after being preserved in 70% alcohol, were processed according to the generally accepted histological procedure and embedded in paraffin. Sections 5β7 ΞΌm in thickness were stained with histological stains and examined under a light microscope.Results and discussion. Microstructural analysis of the characteristics of the relationship in the "parasiteβhost" system showed that the mucous membrane of the small intestine of sheep in the presence of P. cervi looks sharply thickened. Swelling of the epithelium of villi and crypts, its vacuolization and albuminoid degeneration were found. In some places, proliferation of the epithelial layer of the mucous membrane was detected, due to which epithelial hyperplasia is observed, in some cases turning into metaplasia. Proliferation and hyperplasia (metaplasia) in the endostation of the host in the presence of the parasite contribute to: 1. stability of the parasite-host system and the participation of trematodes in trophism; 2. determination of the clinical and morphological picture of trematodose; 3. predicting the effects of this pathology on the host. Adhesion in the microstructural complex βtrematode tegument β epithelial tissue of the villi of the small intestineβ in ovine paramphistomosis at the contact level of two glycocalyx layers β the tegument of P. cervi and the surface of the epithelial cells of the villi of the hostβs intestine, as well as single histological staining of the sites of contact between the parasite and the host as a result of mixing the components of the trematode tegument and the tissue of the hostβs small intestine with deep adhesion indicate the established mutual relations between the components of a single system "parasiteβhost".Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ: ΠΈΠ·ΡΡΠΈΡΡ ΠΌΠΈΠΊΡΠΎΡΡΡΡΠΊΡΡΡΠ½ΡΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ Π² ΠΏΡΠΎΡΠ΅ΡΡΠ΅ Π°Π΄Π°ΠΏΡΠ°ΡΠΈΠΈ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠΎΠ² ΠΏΡΠΈ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΡΠΈΡΡΠ΅ΠΌΡ Β«ΠΏΠ°ΡΠ°Π·ΠΈΡβΡ
ΠΎΠ·ΡΠΈΠ½Β» Π½Π° ΠΏΡΠΈΠΌΠ΅ΡΠ΅ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ Paramphistomum cervi Π² ΡΠΎΠ½ΠΊΠΎΠΌ ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ΅ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎ ΠΈΠ½Π²Π°Π·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΎΠ²Π΅Ρ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ ΠΌΠΈΠΊΡΠΎΡΡΡΡΠΊΡΡΡΡ ΡΠΎΠ½ΠΊΠΎΠΉ ΠΊΠΈΡΠΊΠΈ Π² ΡΠΈΡΡΠ΅ΠΌΠ΅ Β«ΠΏΠ°ΡΠ°Π·ΠΈΡβΡ
ΠΎΠ·ΡΠΈΠ½Β» Π½Π° ΠΏΡΠΈΠΌΠ΅ΡΠ΅ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ P. cervi Π² ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ΅ ΠΎΠ²Π΅Ρ ΠΈΠ·ΡΡΠ°Π»ΠΈ ΠΏΡΠΈ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠΈ ΠΎΠ±ΡΠ΅ΠΈΠ·Π²Π΅ΡΡΠ½ΡΡ
Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ². ΠΡΡΠΎΡΠΊΠΈ ΡΠΊΠ°Π½ΠΈ ΡΠΎΠ½ΠΊΠΎΠΉ ΠΊΠΈΡΠΊΠΈ ΠΎΠ²Π΅Ρ Ρ P. cervi (Zeder, 1790) ΠΏΠΎΡΠ»Π΅ ΡΠΈΠΊΡΠ°ΡΠΈΠΈ Π² 70%-Π½ΠΎΠΌ ΡΠΏΠΈΡΡΠ΅ ΠΎΠ±ΡΠ°Π±Π°ΡΡΠ²Π°Π»ΠΈ ΠΏΠΎ ΠΎΠ±ΡΠ΅ΠΏΡΠΈΠ½ΡΡΠΎΠΉ Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠ΅ ΠΈ Π·Π°Π»ΠΈΠ²Π°Π»ΠΈ Π² ΠΏΠ°ΡΠ°ΡΠΈΠ½. Π‘ΡΠ΅Π·Ρ ΡΠΎΠ»ΡΠΈΠ½ΠΎΠΉ 5β7 ΠΌΠΊΠΌ ΠΎΠΊΡΠ°ΡΠΈΠ²Π°Π»ΠΈ Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΠΊΡΠ°ΡΠΈΡΠ΅Π»ΡΠΌΠΈ ΠΈ ΠΈΠ·ΡΡΠ°Π»ΠΈ Π² ΡΠ²Π΅ΡΠΎΠ²ΠΎΠΌ ΠΌΠΈΠΊΡΠΎΡΠΊΠΎΠΏΠ΅.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅. ΠΠΈΠΊΡΠΎΡΡΡΡΠΊΡΡΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠ΅ΠΉ Π²Π·Π°ΠΈΠΌΠΎΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΡ Π² ΡΠΈΡΡΠ΅ΠΌΠ΅ Β«ΠΏΠ°ΡΠ°Π·ΠΈΡβΡ
ΠΎΠ·ΡΠΈΠ½Β» ΠΏΠΎΠΊΠ°Π·Π°Π», ΡΡΠΎ ΡΠ»ΠΈΠ·ΠΈΡΡΠ°Ρ ΠΎΠ±ΠΎΠ»ΠΎΡΠΊΠ° ΡΠΎΠ½ΠΊΠΎΠΉ ΠΊΠΈΡΠΊΠΈ ΠΎΠ²Π΅Ρ Π² ΠΏΡΠΈΡΡΡΡΡΠ²ΠΈΠΈ P. cervi Π²ΡΠ³Π»ΡΠ΄ΠΈΡ ΡΠ΅Π·ΠΊΠΎ ΡΡΠΎΠ»ΡΡΠ½Π½ΠΎΠΉ. ΠΠ±Π½Π°ΡΡΠΆΠ΅Π½ΠΎ Π½Π°Π±ΡΡ
Π°Π½ΠΈΠ΅ ΡΠΏΠΈΡΠ΅Π»ΠΈΡ Π²ΠΎΡΡΠΈΠ½ΠΎΠΊ ΠΈ ΠΊΡΠΈΠΏΡ, Π΅Π³ΠΎ Π²Π°ΠΊΡΠΎΠ»ΠΈΠ·Π°ΡΠΈΡ ΠΈ Π·Π΅ΡΠ½ΠΈΡΡΠ°Ρ Π΄ΠΈΡΡΡΠΎΡΠΈΡ. ΠΠ΅ΡΡΠ°ΠΌΠΈ Π²ΡΡΠ²Π»Π΅Π½Π° ΠΏΡΠΎΠ»ΠΈΡΠ΅ΡΠ°ΡΠΈΡ ΡΠΏΠΈΡΠ΅Π»ΠΈΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΠ»Π°ΡΡΠ° ΡΠ»ΠΈΠ·ΠΈΡΡΠΎΠΉ ΠΎΠ±ΠΎΠ»ΠΎΡΠΊΠΈ, Π·Π° ΡΡΠ΅Ρ ΡΠ΅Π³ΠΎ Π½Π°Π±Π»ΡΠ΄Π°Π΅ΡΡΡ Π³ΠΈΠΏΠ΅ΡΠΏΠ»Π°Π·ΠΈΡ ΡΠΏΠΈΡΠ΅Π»ΠΈΡ, Π² Π½Π΅ΠΊΠΎΡΠΎΡΡΡ
ΡΠ»ΡΡΠ°ΡΡ
ΠΏΠ΅ΡΠ΅Ρ
ΠΎΠ΄ΡΡΠ°Ρ Π² ΠΌΠ΅ΡΠ°ΠΏΠ»Π°Π·ΠΈΡ. ΠΡΠΎΠ»ΠΈΡΠ΅ΡΠ°ΡΠΈΡ ΠΈ Π³ΠΈΠΏΠ΅ΡΠΏΠ»Π°Π·ΠΈΡ (ΠΌΠ΅ΡΠ°ΠΏΠ»Π°Π·ΠΈΡ) Π² ΡΠ½Π΄ΠΎΡΡΠ°ΡΠΈΠΈ Ρ
ΠΎΠ·ΡΠΈΠ½Π° Π² ΠΏΡΠΈΡΡΡΡΡΠ²ΠΈΠΈ ΠΏΠ°ΡΠ°Π·ΠΈΡΠ° ΡΠΏΠΎΡΠΎΠ±ΡΡΠ²ΡΡΡ: 1. ΡΡΠ°Π±ΠΈΠ»ΡΠ½ΠΎΡΡΠΈ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΎ-Ρ
ΠΎΠ·ΡΠΈΠ½Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ ΠΈ ΡΡΠ°ΡΡΠΈΡ Π² ΡΡΠΎΡΠΈΠΊΠ΅ ΡΡΠ΅ΠΌΠ°ΡΠΎΠ΄; 2. ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΎ-ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΊΠ°ΡΡΠΈΠ½Ρ ΡΡΠ΅ΠΌΠ°ΡΠΎΠ΄ΠΎΠ·Π°; 3. ΠΏΡΠΎΠ³Π½ΠΎΠ·ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΠΎΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠΉ Π΄Π°Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ Π΄Π»Ρ Ρ
ΠΎΠ·ΡΠΈΠ½Π°. ΠΠ΄Π³Π΅Π·ΠΈΡ Π² ΠΌΠΈΠΊΡΠΎΡΡΡΡΠΊΡΡΡΠ½ΠΎΠΌ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ΅ Β«ΡΠ΅Π³ΡΠΌΠ΅Π½Ρ ΡΡΠ΅ΠΌΠ°ΡΠΎΠ΄ β ΡΠΏΠΈΡΠ΅Π»ΠΈΠ°Π»ΡΠ½Π°Ρ ΡΠΊΠ°Π½Ρ Π²ΠΎΡΡΠΈΠ½ΠΊΠΈ ΡΠΎΠ½ΠΊΠΎΠΉ ΠΊΠΈΡΠΊΠΈΒ» ΠΏΡΠΈ ΠΏΠ°ΡΠ°ΠΌΡΠΈΡΡΠΎΠΌΠΎΠ·Π΅ ΠΎΠ²Π΅Ρ Π½Π° ΡΡΠΎΠ²Π½Π΅ ΠΊΠΎΠ½ΡΠ°ΠΊΡΠ° Π΄Π²ΡΡ
Π³Π»ΠΈΠΊΠΎΠΊΠ°Π»ΠΈΠΊΡΠ½ΡΡ
ΡΠ»ΠΎΡΠ² β ΡΠ΅Π³ΡΠΌΠ΅Π½ΡΠ° P. cervi ΠΈ ΠΏΠΎΠ²Π΅ΡΡ
Π½ΠΎΡΡΠΈ ΡΠΏΠΈΡΠ΅Π»ΠΈΠ°Π»ΡΠ½ΡΡ
ΠΊΠ»Π΅ΡΠΎΠΊ Π²ΠΎΡΡΠΈΠ½ΠΎΠΊ ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ° Ρ
ΠΎΠ·ΡΠΈΠ½Π°, Π° ΡΠ°ΠΊΠΆΠ΅ Π΅Π΄ΠΈΠ½ΠΎΠ΅ ΠΎΠΊΡΠ°ΡΠΈΠ²Π°Π½ΠΈΠ΅ Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ ΡΡΠ°ΡΡΠΊΠΎΠ² ΠΊΠΎΠ½ΡΠ°ΠΊΡΠ° ΠΏΠ°ΡΠ°Π·ΠΈΡΠ° ΠΈ Ρ
ΠΎΠ·ΡΠΈΠ½Π° Π² ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΡΠΌΠ΅ΡΠΈΠ²Π°Π½ΠΈΡ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠΎΠ² ΡΠ΅Π³ΡΠΌΠ΅Π½ΡΠ° ΡΡΠ΅ΠΌΠ°ΡΠΎΠ΄ ΠΈ ΡΠΊΠ°Π½ΠΈ ΡΠΎΠ½ΠΊΠΎΠΉ ΠΊΠΈΡΠΊΠΈ Ρ
ΠΎΠ·ΡΠΈΠ½Π° ΠΏΡΠΈ Π³Π»ΡΠ±ΠΎΠΊΠΎΠΉ Π°Π΄Π³Π΅Π·ΠΈΠΈ, ΡΠΊΠ°Π·ΡΠ²Π°Π΅Ρ Π½Π° ΡΠΎΡΡΠΎΡΠ²ΡΠΈΠ΅ΡΡ Π²Π·Π°ΠΈΠΌΠ½ΡΠ΅ ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΡ ΠΌΠ΅ΠΆΠ΄Ρ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠ°ΠΌΠΈ Π΅Π΄ΠΈΠ½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ Β«ΠΏΠ°ΡΠ°Π·ΠΈΡβΡ
ΠΎΠ·ΡΠΈΠ½Β»
Psychomotor Impairments in Experimental Animals in the Cases of Opisthorchosis
The purpose of the research is to study adaptative and neurological onsets in the behavior of animals infected by Opisthorchis felineus. Materials and methods. The research was conducted on 10 buck rabbits orally infected by metacercariae O. felineus in a dose of 50 specimen per one animal. 9 health breeding stock animals were the control. Infection was confirmed by laboratory research of feces after 1.5 months with the detection of trematode ootids. The research of psychomotor reactions β somatosensorial, visile (photic), sound with evaluation of general animal reaction, their behavior and response of organs of senses was conducted after 4 months.Results and discussion. Aggressively-destructive disorders were established in the primary reaction to contact, in which the two-phase behavior is established, a short phase of aggression, alternating with a long inhibitory phase. Anxiety state showing in disorientation of movements, head turning in combination with the reaction of exclusion has been established in infected animals. Disorientation, active motor behavior similar to attack (aggression), ears pressing was noted when applying photic stimuli. Absence of forced squeezing, the reaction of the third eyelid was observed when taking into account reactions of eye assist device on photic stimulus. Absence of suspension reaction, anxiety was established under exposer of sound stimuli in animals, presence of loginess and absence of the reaction. Thus, psychomotor disorders apparently associated with toxic hepatic encephalopathy and general subcompensated dysfunction of the nervous system was noted in the cases of opisthorchosis after 4 months
CLINICAL ASPECTS OF ACUTE OPISTHORCHIASIS IN RABBITS IN THE EXPERIMENT
Objective of research: to investigate the clinical features of acute opisthorchiasis in rabbits.Materials and methods: Clinical evidence of acute opisthorchiasis in rabbits, laboratory blood tests.Results and discussion: Skin lesions in the form of cracks and ulcers of various sizes in the neck, thoracic back and croup, mostly localized along the spine, were clinically identified in acute opisthorchiasis of rabbits. Weight loss within the first month was up to 300 β500 grams. Laboratory tests showed that one month later, the level of blood glucose in the infected animals was 3 times higher than in controls. Compared with the controls, a reduced number of red blood cells and hemoglobin level in animals of the experimental group was observed, leukopenia was determined. The blood coagulation time was significantly accelerated
Adaptation of the Relationship in the "ParasiteβHost" System with Parasitism <i>Paramphistomum Ρervi</i> in the Small Intestine of Sheeps
The purpose of the research is studying microstructural changes in the process of adaptation of components during the formation of the βparasiteβhostβ system by the example of Paramphistomum cervi (Zeder, 1790) parasitizing in the small intestine of spontaneously infected sheep.Materials and methods. Peculiarities of changes in the microstructure of the small intestine in the βparasiteβhostβ system were studied using parasitization of P. cervi in the intestines of sheep using well-known histological methods. Pieces of tissue of the small intestine of sheep with P. cervi, after being preserved in 70% alcohol, were processed according to the generally accepted histological procedure and embedded in paraffin. Sections 5β7 ΞΌm in thickness were stained with histological stains and examined under a light microscope.Results and discussion. Microstructural analysis of the characteristics of the relationship in the "parasiteβhost" system showed that the mucous membrane of the small intestine of sheep in the presence of P. cervi looks sharply thickened. Swelling of the epithelium of villi and crypts, its vacuolization and albuminoid degeneration were found. In some places, proliferation of the epithelial layer of the mucous membrane was detected, due to which epithelial hyperplasia is observed, in some cases turning into metaplasia. Proliferation and hyperplasia (metaplasia) in the endostation of the host in the presence of the parasite contribute to: 1. stability of the parasite-host system and the participation of trematodes in trophism; 2. determination of the clinical and morphological picture of trematodose; 3. predicting the effects of this pathology on the host. Adhesion in the microstructural complex βtrematode tegument β epithelial tissue of the villi of the small intestineβ in ovine paramphistomosis at the contact level of two glycocalyx layers β the tegument of P. cervi and the surface of the epithelial cells of the villi of the hostβs intestine, as well as single histological staining of the sites of contact between the parasite and the host as a result of mixing the components of the trematode tegument and the tissue of the hostβs small intestine with deep adhesion indicate the established mutual relations between the components of a single system "parasiteβhost"