320 research outputs found
A position servomechanism with the gain modulated by the output velocity
Call number: LD2668 .T4 1960 S7
Stable ResNet
Deep ResNet architectures have achieved state of the art performance on many
tasks. While they solve the problem of gradient vanishing, they might suffer
from gradient exploding as the depth becomes large (Yang et al. 2017).
Moreover, recent results have shown that ResNet might lose expressivity as the
depth goes to infinity (Yang et al. 2017, Hayou et al. 2019). To resolve these
issues, we introduce a new class of ResNet architectures, called Stable ResNet,
that have the property of stabilizing the gradient while ensuring expressivity
in the infinite depth limit.Comment: 43 pages, 4 figure
How Tuning Interfaces Impacts the Dynamics and Structure of Polymer Nanocomposites Simultaneously
Fundamental understanding of macroscopic properties of polymer nanocomposites
(PNCs) remains difficult due to the complex interplay of microscopic dynamics
and structure, namely interfacial layer relaxations and three-dimensional
nanoparticle arrangements. The effect of surface modification by alkyl
methoxysilanes at different grafting densities has been studied in PNCs made of
poly(2-vinylpyridine) and spherical 20 nm silica nanoparticles (NPs). The
segmental dynamics has been probed by broadband dielectric spectroscopy, and
the filler structure by small-angle X-ray scattering and reverse Monte Carlo
simulations. By combining the particle configurations with the interfacial
layer properties, it is shown how surface modification tunes the attractive
polymer-particle interactions: bare NPs slow down the polymer interfacial layer
dynamics over a thickness of ca. 5 nm, while grafting screens these
interactions. Our analysis of interparticle spacing and segmental dynamics
provides unprecedented insight into the effect of surface modification on the
main characteristics of PNCs: particle interactions and polymer interfacial
layers
An Evening of Jazz
Program listing performers and works performe
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MALDI analysis of estane degradation
SEUMALDI has been successfully used to accurately measure the MW of hydrolysis degradation products from Estane 5703. Reasonable structure assignments have been made to the degradation products and several observations reported. Most of the low MW degradation peaks have been identified as ester hydrolysis fragments. The data suggest that the polyester macrodiol may be shorter than the {approximately}2000 amu reported by the manufacturer. Experiments are ongoing to determine if hydrolysis occurs within the material's applied environment
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Analysis of the genome of leporid herpesvirus 4
The genome of a herpesvirus highly pathogenic to rabbits, leporid herpesvirus 4 (LHV-4), was analyzed using high-throughput DNA sequencing technology and primer walking. The assembled DNA sequences were further verified by restriction endonuclease digestion and Southern blot analyses. The total length of the LHV-4 genome was determined to be about 124 kb. Genes encoded in the LHV-4 genome are most closely related to herpesvirus of the Simplexvirus genus, including human herpesviruses (HHV-1 and HHV-2), monkey herpesviruses including cercopithicine (CeHV-2 and CeHV-16), macacine (McHV-1), bovine herpesvirus 2 (BHV-2), and a lineage of wallaby (macropodid) herpesviruses (MaHV-1 and -2). Similar to other simplexvirus genomes, LHV-4 has a high overall G+C content of 65–70% in the unique regions and 75–77% in the inverted repeat regions. Orthologs of ICP34.5 and US5 were not identified in the LHV-4 genome. This study shows that LHV-4 has the smallest simplexvirus genome characterized to date.Keywords: LHV-4, Genome, Sequencin
Discarded livers tested by normothermic machine perfusion in the VITTAL trial:Secondary end points and 5-year outcomes
Normothermic machine perfusion (NMP) enables pretransplant assessment of high-risk donor livers. The VITTAL trial demonstrated that 71% of the currently discarded organs could be transplanted with 100% 90-day patient and graft survivals. Here, we report secondary end points and 5-year outcomes of this prospective, open-label, phase 2 adaptive single-arm study. The patient and graft survivals at 60 months were 82% and 72%, respectively. Four patients lost their graft due to nonanastomotic biliary strictures, one caused by hepatic artery thrombosis in a liver donated following brain death, and 3 in elderly livers donated after circulatory death (DCD), which all clinically manifested within 6 months after transplantation. There were no late graft losses for other reasons. All the 4 patients who died during the study follow-up had functioning grafts. Nonanastomotic biliary strictures developed in donated after circulatory death livers that failed to produce bile with pH >7.65 and bicarbonate levels >25 mmol/L. Histological assessment in these livers revealed high bile duct injury scores characterized by arterial medial necrosis. The quality of life at 6 months significantly improved in all but 4 patients suffering from nonanastomotic biliary strictures. This first report of long-term outcomes of high-risk livers assessed by normothermic machine perfusion demonstrated excellent 5-year survival without adverse effects in all organs functioning beyond 1 year (ClinicalTrials.gov number NCT02740608).</p
The \u3cem\u3eChlamydomonas\u3c/em\u3e Genome Reveals the Evolution of Key Animal and Plant Functions
Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the ∼120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella
A Cross-Cultural Comparison of Business Complaint Management Expectations
This paper is in closed access until 9th Dec 2016.Copyright © Taylor and Francis Group, LLC. This study explores the complaint management expectations of 72 British and 74 German organizational buyers using automated online means-end laddering and a Hierarchical Value Map presentation. It conceptualizes the links between expected complaint resolution attributes by the buyer (i.e., means) and the buyer's value perceptions (i.e., ends). Unlike previous research, we highlight similarities and differences in the drivers behind and attributes of complaint management expectations across two countries (Germany and the United Kingdom). Even in countries appearing to be similar economically and culturally, we find differences in the desired attributes. British buyers, for example, emphasize softer complaint resolution attributes compared to Germans. Our study is the first to present a model of complaint management expectations incorporating the role of culture, and it provides managerial directions on standardization and adaption of complaint resolution attributes. Furthermore, it evaluates justice dimensions (especially interactional justice) and their impact on perceptions of complaint management
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