Review of \u3ci\u3eTheir Own Frontier: Women Intellectuals Re-Visioning the American West\u3c/i\u3e Edited and with an introduction by Shirley A. Leckie and Nancy J. Parezo

Pioneering women ethnohistorians and anthropologists who studied American Indians and the trans-Mississippi West deserve greater recognition, not only for the important information they gathered but also for their theoretical insights and methodological advances. As we learn about these women\u27s lives and scholarly contributions, we also come to understand the barriers and prejudices they dealt with in order to pursue the work they valued. This is the argument of Shirley Leckie and Nancy Parezo\u27s collection of intellectual biographies of ten women, born between 1873 and 1910, whose active research careers spanned most of the twentieth century. Their Own Frontier extends the scope of cultural anthropologist Parezo\u27s earlier Hidden Scholars: Women Anthropologists and the Native American Southwest (1993) into the Great Plains and the discipline of history (coeditor Leckie is a historian), although anthropologists remain in the majority

Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer

Survival rates from colorectal cancer (CRC) differ dramatically according to the stage of the tumor at diagnosis, with survival rates of 90% for patients with stage I disease but only 49% for those with stage III cancer. Many serum and tumor markers have been identified but none has provided a significant improvement over tumor stage as a prognostic indicator for cancer recurrence for patients with stage II or III disease. Aberrant activation of the hepatocyte growth factor (HGF)/HGF receptor (MET) signaling pathway is associated with both malignant transformation and metastatic potential of CRC. MACC1 (metastasis-associated in colon cancer-1) is a newly discovered gene that regulates this signaling cascade. The significant correlation between overexpression of MACC1 in CRC and both malignant transformation and subsequent risk for metastases in stage II and III CRC indicates that MACC1 tumor typing may prove valuable for determining risk for CRC recurrence. MACC1 may also be an important therapeutic target for CRC treatment

Modeling Nonlinear Heat Transfer for a Pin-on-Disc Sliding System

The objective of this research is to develop a numerical method to characterize heat transfer and wear rates for samples of Vascomax® 300, or Maraging 300, steel. A pin-on-disc experiment was conducted in which samples were exposed to a high-pressure, high-speed, sliding contact environment. This sliding contact generates frictional heating that influences the temperature distribution and wear characteristics of the test samples. A two-dimensional nonlinear heat transfer equation is discretized and solved via a second-order explicit finite difference scheme to predict the transient temperature distribution of the pin. This schematic is used to predict the removal of material from the specimens over time based on the temperature profile of the pin. The solutions presented also consider the experimental data and are used to determine characteristics of the contact interface and pin surface associated with the material removal process

Intermodulation distortion from receiver non-linear phase characteristics Final report

Computation of intermodulation distortion levels produced by telemetry system predetection filte

Gyrotropic impact upon negatively refracting surfaces

Surface wave propagation at the interface between different types of gyrotropic materials and an isotropic negatively refracting medium, in which the relative permittivity and relative permeability are, simultaneously, negative is investigated. A general approach is taken that embraces both gyroelectric and gyromagnetic materials, permitting the possibility of operating in either the low GHz, THz or the optical frequency regimes. The classical transverse Voigt configuration is adopted and a complete analysis of non-reciprocal surface wave dispersion is presented. The impact of the surface polariton modes upon the reflection of both plane waves and beams is discussed in terms of resonances and an example of the influence upon the Goos–Hänchen shift is given

Homology of E_n Ring Spectra and Iterated THH

We describe an iterable construction of THH for an E_n ring spectrum. The reduced version is an iterable bar construction and its n-th iterate gives a model for the shifted cotangent complex at the augmentation, representing reduced topological Quillen homology of an augmented E_n algebra.Comment: Some additional exposition added. Minor correction

Permutative categories, multicategories, and algebraic K-theory

We show that the $K$-theory construction of arXiv:math/0403403, which preserves multiplicative structure, extends to a symmetric monoidal closed bicomplete source category, with the multiplicative structure still preserved. The source category of arXiv:math/0403403, whose objects are permutative categories, maps fully and faithfully to the new source category, whose objects are (based) multicategories