343 research outputs found

    Rapid Cycling of Autophosphorylation of a Ca 2+

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    Symbolic power: the future of nuclear energy in Lithuania

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    EU accession states may have thrown off their Soviet past in political terms, but abandoning some of the Soviet era technologies is proving to be harder. Civil nuclear power is on the way out in most of Europe, but for some ex-Soviet countries this may present serious problems of economic, social and cultural transformation -- especially in countries like Lithuania, where nuclear power supplies the bulk of the electricity. The issue has come to a head given the EU's insistence that several ex-Soviet states must agree to close their nuclear plant as a condition of EU entry. Lithuania is the accession country most wedded to and certainly most reliant on nuclear power. It has a nuclear plant which uses a technology (the RBMK, Chernobyl-type reactor) which the EU has insisted should be closed rapidly on safety grounds. This has proved an unpopular requirement in Lithuania for a variety of reasons. There are problem with ensuring continued energy supplies and replacing the lost employment and earning power. However Lithuania also has a more general commitment to this technology as a symbol of national prowess and independence. During and immediately after the struggle for national independence in 1991, the country had a mass anti-nuclear movement. This has been analysed as a covert expression of nationalist and anti-Soviet feeling, given that most opposition to nuclear power evaporated after independence (Dawson 1996). Subsequently the EU ruled that Lithuania's Ignalina nuclear plant should be closed. Yet now it is widely seen as a national asset, a view reinforced by resentment about the EU apparently imposing an unwarranted closure policy. This article will analyse how public and policy views on nuclear power have changed over time in Lithuania and how its symbolic meaning has changed during different phases of transformation of the Lithuanian society

    European Paediatric Formulation Initiative workshop report: Improving the administration of oral liquid medicines in paediatrics using dosing syringes and enteral accessories

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    Accurate dosing of the right medicine to the right patient is a key element of safe and efficacious pharmacotherapy, yet prone to technical challenges and human error when dosing involves the administration of small volumes of liquid medicines. For this reason, the topic has gained increased attention over the last decade from multiple stakeholder parties e.g. academia, hospital pharmacy, the medical device and pharmaceutical industry, and regulatory agencies. It is now well acknowledged that spoons and cups are not suitable for the measurement of small volumes of oral liquid medicines and that syringes are a better alternative, but syringes for parenteral use should not be used for oral dosing in order to avoid accidental parenteral delivery of oral products. However, dosing accuracy of very small volumes of liquid medicines to young children, and especially pre-term neonates, is still not sufficiently ensured. A workshop was organised in 2018 by the European Paediatric Formulation Initiative to reflect on current status and challenges (first part) and possible strategies to improve the present situation (second part). A voting system (n = 24) was used to consider the most favourable solutions. The harmonisation and/or standardisation of the technical design of oral syringes (including e.g. female/male connection) was considered a key priority

    Spatial trends on an ungrazed West Cumbrian saltmarsh of surface contamination by selected radionuclides over a 25 year period

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    Long term spatial and temporal variations in radionuclide activity have been measured in a contaminated ungrazed saltmarsh near Ravenglass, Cumbria. Over a twenty–five year period there has been a decrease in activity concentration with 106Ru and 137Cs showing the highest rate of change followed by Pu alpha and 241Am. A number of factors contribute to the reduction with time; including radiological half lives, discharge and remobilisation. For 241Am the lower reduction rate is partially due to ingrowth from 241Pu and partially as a result of transport of sediment from the offshore Irish Sea mud patch. Considerable spatial variation for the different radionuclides was observed, which with time became less defined. The highest activity concentrations of long-lived radionuclides were in low energy areas, typically where higher rates of sedimentation and vegetation occurred. The trend was reversed for the shorter lived radionuclide, 106Ru, with higher activity concentrations observed in high energy areas where there was frequent tidal inundation. Surface scrape samples provide a pragmatic, practical method of measuring sediment contamination over large areas and is a sampling approach adopted by most routine environmental monitoring programs, but it does not allow for interpretation of the effect of variation in sedimentation rates. This paper proposes a method for calculating indicative sedimentation rates across the saltmarsh using surface scrape data, which produces results consistent with values experimentally obtained

    Birmingham’s Eastside story: making steps towards sustainability?

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    Sustainability has come to play a dominant discursive role in the UK planning system, particularly relating to urban regeneration. The purpose of this paper is to evaluate the role that sustainability plays in a major regeneration programme, known as Eastside, currently underway in Birmingham, the UK. That this £6 billion redevelopment is now widely talked about by such key players as Birmingham City Council and the Regional Development Agency, Advantage West Midlands, as having a central sustainability agenda points to the growing importance of the ideal of sustainability in planning and regeneration agendas. In this paper, we investigate in detail how and why sustainability has become part of the planning discourse for Eastside and critically evaluate what impact, if any, this is having on public policy decision-making

    Comparing nuclear power trajectories in Germany and the UK: from ‘regimes' to ‘democracies’ in sociotechnical transitions and Discontinuities

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    This paper focuses on arguably the single most striking contrast in contemporary major energy politics in Europe (and even the developed world as a whole): the starkly differing civil nuclear policies of Germany and the UK. Germany is seeking entirely to phase out nuclear power by 2022. Yet the UK advocates a ‘nuclear renaissance’, promoting the most ambitious new nuclear construction programme in Western Europe.Here,this paper poses a simple yet quite fundamental question: what are the particular divergent conditions most strongly implicated in the contrasting developments in these two countries. With nuclear playing such an iconic role in historical discussions over technological continuity and transformation, answering this may assist in wider understandings of sociotechnical incumbency and discontinuity in the burgeoning field of‘sustainability transitions’. To this end, an ‘abductive’ approach is taken: deploying nine potentially relevant criteria for understanding the different directions pursued in Germany and the UK. Together constituted by 30 parameters spanning literatures related to socio-technical regimes in general as well as nuclear technology in particular, the criteria are divided into those that are ‘internal’ and ‘external’ to the ‘focal regime configuration’ of nuclear power and associated ‘challenger technologies’ like renewables. It is ‘internal’ criteria that are emphasised in conventional sociotechnical regime theory, with ‘external’ criteria relatively less well explored. Asking under each criterion whether attempted discontinuation of nuclear power would be more likely in Germany or the UK, a clear picture emerges. ‘Internal’ criteria suggest attempted nuclear discontinuation should be more likely in the UK than in Germany– the reverse of what is occurring. ‘External’ criteria are more aligned with observed dynamics –especially those relating to military nuclear commitments and broader ‘qualities of democracy’. Despite many differences of framing concerning exactly what constitutes ‘democracy’, a rich political science literature on this point is unanimous in characterising Germany more positively than the UK. Although based only on a single case,a potentially important question is nonetheless raised as to whether sociotechnical regime theory might usefully give greater attention to the general importance of various aspects of democracy in constituting conditions for significant technological discontinuities and transformations. If so, the policy implications are significant. A number of important areas are identified for future research, including the roles of diverse understandings and specific aspects of democracy and the particular relevance of military nuclear commitments– whose under-discussion in civil nuclear policy literatures raises its own questions of democratic accountability

    Dual fast-cycling superconducting synchrotron at Fermilab and a possible path to the future of high energy particle physics

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    We briefly outline shorter and longer term physics motivation for constructing a dual, fast-cycling superconducting synchrotron accelerator (DSFMR - Dual Super-Ferric Main Ring) in the Tevatron tunnel at Fermilab. We discuss using this accelerator as a high-intensity dual neutrino beam source for the long-baseline neutrino oscillation search experiments, and also as a fast, dual pre-injector accelerator for the VLHC (Very Large Hadron Collider)
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