L’angiostrongylose humaine : une maladie tropicale négligée

International audienc

Whiptail Stingray Injury

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Post-Malaria Neurologic Syndrome: A Rare Pediatric Case Report

Post-malaria neurologic syndrome (PMNS) is a rare complication following a Plasmodium falciparum infection and its pathophysiology remains unclear. This is the first report of a pediatric PMNS following an infection acquired in Africa and the fourth description of pediatric PMNS overall. Neither intrathecal synthesis of Immunoglobin G nor specific P. falciparum antibodies were found in the cerebrospinal fluid

SARS-CoV-2 with Panton-Valentine leukocidin-producing Staphylococcus aureus healthcare-associated pneumonia in the Indian Ocean

At this time, the literature reports only one case of superinfection with Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus in a patient with severe acute respiratory distress syndrome secondary to coronavirus 2 (SARS-CoV-2) pneumonia. Here we report the first two cases of PVL-producing S. aureus healthcareassociated pneumonia in patients hospitalized for SARS-CoV-2 pneumonia in the Indian Ocean region. The two isolated strains of S. aureus were found to belong to the ST152/t355 clone, a known PVL-producing S. aureus clone that circulates in Africa and is responsible for infections imported into Europe. Our two cases reinforce the hypothesis that SARS-CoV-2 infection favors the occurrence of PVL-producing S. aureus pneumonia. Production of PVL should be searched in patients returning from the Indian Ocean region who present with severe SARS-CoV-2 pneumonia complicated by superinfection with S. aureus even in the case of late onset healthcare-associated pneumonia Dear Editor, Bacterial superinfections in patients with severe acute respiratory distress syndrome secondary to coronavirus 2 (SARS-CoV-2) pneumonia are relatively rare and are often caused by Staphylococcus aureus [1]. At this time, the literature reports only one case of superinfection with Panton-Valentine leukocidin (PVL)-producing S. aureus in a patient with SARS-CoV-2 pneumonia[2]. Here we report the first two cases of PVL-producing S. aureus healthcare-associated pneumonia in patients hospitalized for SARS-CoV-2 pneumonia in the Indian Ocean region

Angiostrongylus cantonensis Infection on Mayotte Island, Indian Ocean, 2007-2012

International audienceHuman angiostrongyliasis (HA) is a neurological helminthic disease caused by the lung worm Angiostrongylus cantonensis. It is suspected in the combination of travel or a residence in an endemic area and eosinophilic meningitis. In Mayotte, an island in the Indian Ocean, cases are rare but regular. The main objective of our study was to describe the epidemiological and diagnosis clues of HA in Mayotte. The secondary objectives were to evaluate the contribution of Real-Time Polymerase Chain Reaction (RT- PCR) for the diagnosis of HA, delineate the characteristics of the local transmission and ascertain the presence of A. cantonensis in Achatina fulica, the potential vector of the disease

Amplification curves of six patients positive by Polymerase Chain Reaction and the positive control.

<p>Amplification curves of six patients positive by Polymerase Chain Reaction and the positive control.</p

Characteristics of the 14 children with nervous angiostrongyliasis and comparison with the 3 main available paediatric series in the literature.

<p>Characteristics of the 14 children with nervous angiostrongyliasis and comparison with the 3 main available paediatric series in the literature.</p

Monthly repartition of the cases and average pluviometry.

<p>Monthly repartition of the cases and average pluviometry.</p

Flow chart of the study.

<p><i>Ac</i>: <i>Angiostrongylus cantonensis</i>; CSF: Cerebrospinal fluid; PCR: Polymerase Chain Reaction. * Eosinophilic meningitis: ≥ 10 eosinophils /mm3 in CSF or ≥10% WBC). ** Meningitis: ≥ 10 WBC in CSF.</p