1,641 research outputs found
A METHOD FOR DETERMINING RANCH PROFIT PROBABILITIES WHEN LIVESTOCK YIELDS ARE NORMALLY DISTRIBUTED
Data on net turnoff for small, medium-sized and large cow-calf and small and large size yearling ranches were tested for normality using the Shapiro - Wilk test. The yield data examined were accepted as normally distributed at the alpha = .10 level. The probability of profit for each type of ranch was assessed using normal curve techniques for nine different cost-price alternatives and weather conditions. Yearling cattle ranchers had higher profit probabilities than cow-calf ranchers. Prices received had more influence on profit probabilities than weather conditions.Livestock Production/Industries,
Opportunistic detection of atrial fibrillation using blood pressure monitors: a systematic review
Background: Atrial Fibrillation (AF) affects around 2% of the population and early detection is beneficial, allowing patients to begin potentially life-saving anticoagulant therapies. Blood pressure (BP) monitors may offer an opportunity to screen for AF. Aim: To identify and appraise studies which report the diagnostic accuracy of automated BP monitors used for opportunistic AF detection. Methods: A systematic search was performed of the Medline, Medline-in-process and Embase literature databases. Papers were eligible if they described primary studies of the evaluation of a BP device for AF detection, were published in a peer reviewed journal and reported values for the sensitivity and specificity. Included studies were appraised using the QUADAS-2 tool to assess their risk of bias and applicability to opportunistic AF detection. Values for the sensitivity and specificity of AF detection were extracted from each paper and compared. Results and Conclusion: We identified seven papers evaluating six devices from two manufacturers. Only one study scored low risk in all of the QUADAS-2 domains. All studies reported specificity greater than 85% and six reported sensitivity greater than 90%. The studies showed that blood pressure devices with embedded algorithms for detecting arrhythmias show promise as screening tools for AF, comparing favourably with manual pulse palpation. But the studies used different methodologies and many were subject to potential bias. More studies are needed to more precisely define the sensitivity and specificity of opportunistic screening for AF during blood pressure measurement before its clinical utility in the population of interest can be assessed fully
Accuracy of pulse interval timing in ambulatory blood pressure measurement
Blood pressure (BP) monitors rely on pulse detection. Some blood pressure monitors use pulse timings to analyse pulse interval variability for arrhythmia screening, but this assumes that the pulse interval timings detected from BP cuffs are accurate compared with RR intervals derived from ECG. In this study we compared the accuracy of pulse intervals detected using an ambulatory blood pressure monitor (ABPM) with single lead ECG. Twenty participants wore an ABPM for three hours and a data logger which synchronously measured cuff pressure and ECG. RR intervals were compared with corresponding intervals derived from the cuff pressure tracings using three different pulse landmarks. Linear mixed effects models were used to assess differences between ECG and cuff pressure timings and to investigate the effect of potential covariates. In addition, the maximum number of successive oscillometric beats detectable in a measurement was assessed. From 243 BP measurements, the foot landmark of the oscillometric pulse was found to be associated with fewest covariates and had a random error of 9.5 ms. 99% of the cuff pressure recordings had more than 10 successive detectable oscillometric beats. RR intervals can be accurately estimated using an ABPM
On the assessment of blood velocity and wall shear rate in arteries with Doppler ultrasound: a validation study
Cardiovascular disease, mostly atherosclerosis, is responsible for one third of all deaths globally,
rising to more than 50% in the Western World. Risk factors include smoking, diet, and
familial history. Doppler ultrasound can provide estimates of blood velocity and wall shear
rate. Clinically, maximum velocity is used to categorise patients for surgery, although Doppler
velocity measurement is prone to errors and in need of validation. Wall shear stressâwhich
can be derived from wall shear rateâplays a role in disease initiation and progression, although
its clinical utility is unclear due to difficulties associated with its measurement.
This thesis investigates the use of Doppler ultrasound as a tool to estimate blood velocity and
wall shear rate. A simplified method for estimation of wall shear rate in healthy arteries is
developed that uses spectral Doppler ultrasound. This method is based upon the theory of
oscillatory flow in rigid pipes, requiring two measurements that are readily available with clinical
ultrasound machines. This method is compared to a similar method based on colour flow
imaging. The spectral Doppler method underestimated the theoretic value of wall shear rate by
between 7 and 22%, with results varying between phantoms. Errors for the colour method were
on average 35% greater. Test measurements from one healthy volunteer demonstrated that this
method can be applied in-vivo.
In more advanced stages of disease, peak velocity distal to a stenosis is of clinical interest and
the simplified method for wall shear rate estimation is invalid. Steady flow in a series of simplified
stenosis geometries was studied using a dual-beam Doppler system to obtain velocity
vectors. These measurements were compared with data from an equivalent system that used
particle image velocimetry (PIV) and was considered the gold standard. For Reynolds numbers
at the stenosis throat of less than 800, flow remained laminar over the region studied, although
distal flow separation did occur. For higher throat Reynolds numbersâcorresponding to more
severe stenoses or increased flow ratesâasymmetric recirculation regions developed; the transition
to turbulence occurred more proximally, with a corresponding reduction in stenotic jet
and recirculation length.
Qualitative agreement was observed in the velocity profile shapes measured using ultrasound
and PIV at throat Reynolds numbers less than 800. Above this threshold the qualitative agreement
between the velocity profiles became poorer as both downstream distance and the degree
of stenosis increased. Peak axial velocity distal to the stenosis was underestimated, on average,
by 15% in the ultrasound system. Estimation of shear rate remained difficult with both experimental
techniques. Under a Newtonian approximation, the normalised wall shear stresses
agree qualitatively. Under pulsatile flow conditions using an idealised flow waveform, superior
qualitative agreement was observed in the velocity profiles at diastole than at systole. Similar
to the steady flow behaviour, this agreement deteriorated with stenosis severity.
The current generation of clinical ultrasound machines are capable of estimating the wall shear
rate in healthy arteries. In the presence of significant arterial disease, errors in the peak velocity
may result in mis-selection of patients for surgery, while estimation of the wall shear stress
remains extremely problematic; particularly with identifying the wall location and measuring
velocities close to the wall
Research Note, March 1968
This is issue 7: Natural Distribution of Western Larch and Subalpine Larchhttps://scholarworks.umt.edu/montana_forestry_notes/1006/thumbnail.jp
Size-resolved aerosol and cloud condensation nuclei (CCN) properties in the remote marine South China Sea - Part 1: Observations and source classification
Abstract. Ship-based measurements of aerosol and cloud condensation nuclei (CCN) properties are presented for 2 weeks of observations in remote marine regions of the South China Sea/East Sea during the southwestern monsoon (SWM) season. Smoke from extensive biomass burning throughout the Maritime Continent advected into this region during the SWM, where it was mixed with anthropogenic continental pollution and emissions from heavy shipping activities. Eight aerosol types were identified using a k-means cluster analysis with data from a size-resolved CCN characterization system. Interpretation of the clusters was supplemented by additional onboard aerosol and meteorological measurements, satellite, and model products for the region. A typical bimodal marine boundary layer background aerosol population was identified and observed mixing with accumulation mode aerosol from other sources, primarily smoke from fires in Borneo and Sumatra. Hygroscopicity was assessed using the Îș parameter and was found to average 0.40 for samples dominated by aged accumulation mode smoke; 0.65 for accumulation mode marine aerosol; 0.60 in an anthropogenic aerosol plume; and 0.22 during a short period that was characterized by elevated levels of volatile organic compounds not associated with biomass burning impacts. As a special subset of the background marine aerosol, clean air masses substantially scrubbed of particles were observed following heavy precipitation or the passage of squall lines, with changes in observed aerosol properties occurring on the order of minutes. Average CN number concentrations, size distributions, and Îș values are reported for each population type, along with CCN number concentrations for particles that activated at supersaturations between 0.14 and 0.85âŻ%
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Evaluation of simulated O-3 production efficiency during the KORUS-AQ campaign: Implications for anthropogenic NOx emissions in Korea
We examine O3 production and its sensitivity to precursor gases and boundary layer mixing in Korea by using a 3-D global chemistry transport model and extensive observations during the KORea-US cooperative Air Quality field study in Korea, which occurred in MayâJune 2016. During the campaign, observed aromatic species onboard the NASA DC-8 aircraft, especially toluene, showed high mixing ratios of up to 10 ppbv, emphasizing the importance of aromatic chemistry in O3 production. To examine the role of VOCs and NOx in O3 chemistry, we first implement a detailed aromatic chemistry scheme in the model, which reduces the normalized mean bias of simulated O3 mixing ratios from â26% to â13%. Aromatic chemistry also increases the average net O3 production in Korea by 37%. Corrections of daytime PBL heights, which are overestimated in the model compared to lidar observations, increase the net O3 production rate by ~10%. In addition, increasing NOx emissions by 50% in the model shows best performance in reproducing O3 production characteristics, which implies that NOx emissions are underestimated in the current emissions inventory. Sensitivity tests show that a 30% decrease in anthropogenic NOx emissions in Korea increases the O3 production efficiency throughout the country, making rural regions ~2 times more efficient in producing O3 per NOx consumed. Simulated O3 levels overall decrease in the peninsula except for urban and other industrial areas, with the largest increase (~6 ppbv) in the Seoul Metropolitan Area (SMA). However, with simultaneous reductions in both NOx and VOCs emissions by 30%, O3 decreases in most of the country, including the SMA. This implies the importance of concurrent emission reductions for both NOx and VOCs in order to effectively reduce O3 levels in Korea
Major genes for Na(+) exclusion, Nax1 and Nax2 (wheat HKT1;4 and HKT1;5), decrease Na(+) accumulation in bread wheat leaves under saline and waterlogged conditions
Two major genes for Na+ exclusion in durum wheat, Nax1 and Nax2, that were previously identified as the Na+ transporters TmHKT1;4-A2 and TmHKT1;5-A, were transferred into bread wheat in order to increase its capacity to restrict the accumulation of Na+ in leaves. The genes were crossed from tetraploid durum wheat (Triticum turgidum ssp. durum) into hexaploid bread wheat (Triticum aestivum) by interspecific crossing and marker-assisted selection for hexaploid plants containing one or both genes. Nax1 decreased the leaf blade Na+ concentration by 50%, Nax2 decreased it by 30%, and both genes together decreased it by 60%. The signature phenotype of Nax1, the retention of Na+ in leaf sheaths resulting in a high Na+ sheath:blade ratio, was found in the Nax1 lines. This conferred an extra advantage under a combination of waterlogged and saline conditions. The effect of Nax2 on lowering the Na+ concentration in bread wheat was surprising as this gene is very similar to the TaHKT1;5-D Na+ transporter already present in bread wheat, putatively at the Kna1 locus. The results indicate that both Nax genes have the potential to improve the salt tolerance of bread wheat.Richard A. James, Carol Blake, Caitlin S. Byrt, and Rana Munn
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