1,372 research outputs found

    Pasts and pagan practices: moving beyond Stonehenge

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    Theorizing the past is not restricted to archaeology and interpretations of 'past' both influence and are themselves constituted within politicized understandings of self, community and in certain instances, spirituality. 'The past in the imagination of the present' is appropriated, variously, to give meaning to the present or to justify actions and interpret experiences. Summer solstice at Stonehenge, with an estimated 21,000 celebrants in 2005, is only the most publicized appropriation (by pagans and other adherents of alternative spirituality and partying) of a 'sacred site'; and conflicts and negotiations occurring throughout Britain are represented in popular and academic presentations of this 'icon of Britishness'. This paper presents work from the Sacred Sites, Contested Rites/Rights Project (http://www.sacredsites.org.uk) project, a collaboration of archaeology and anthropology informed by pagan and alternative approaches and standpoints investigating and theorizing discourse and practice of heritage management and pagan site users. Whether in negotiations around the Stonehenge solstice access or in dealing with numerous other sites, boundaries between groups or discourses are not clearly drawn - discursive communities merge and re-emerge. But clearly 'past' and 'site' are increasingly important within today's Britain, even as television archaeology increases its following, and pagan numbers continue to grow.</p

    Índice padronizado de precipitação aplicado Ă s condiçÔes de seca no Estado do EspĂ­rito Santo.

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    O Índice Padronizado de Precipitação (SPI) Ă© um dos mĂ©todos mais utilizados para quantificação da seca. A fim de verificar a possibilidade de utilização do SPI no monitoramento das deficiĂȘncias e excessos de precipitação na escala mensal, no Estado do EspĂ­rito Santo objetivou-se, neste trabalho, verificar o ajuste das sĂ©ries temporais dessa variĂĄvel meteorolĂłgica Ă  distribuição gama em cinco localidades do Estado. Por meio dos testes de aderĂȘncia Kolmogorov-Smirnov e qui-quadrado, as sĂ©ries mensais de precipitação pluvial das localidades sob anĂĄlise podem ser consideradas oriundas de uma população com distribuição gama incompleta, permitindo o uso do SPI no monitoramento das condiçÔes de seca meteorolĂłgica. AtravĂ©s de anĂĄlises de autocorrelação e correlação-cruzada, observou-se que a principal caracterĂ­stica das sĂ©ries do SPI Ă© sua grande variabilidade espaço-temporal, a qual indica que em uma mesma regiĂŁo meses extremamente secos podem ser precedidos e/ou seguidos de meses Ășmidos ou normais, e que distintos casos de seca podem ocorrer de forma aleatĂłria, entre as localidades e em um mesmo perĂ­odo

    Mitochondrial Dysfunction in Parkinson's Disease

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    Parkinson's disease (PD) is a progressive, neurodegenerative condition that has increasingly been linked with mitochondrial dysfunction and inhibition of the electron transport chain. This inhibition leads to the generation of reactive oxygen species and depletion of cellular energy levels, which can consequently cause cellular damage and death mediated by oxidative stress and excitotoxicity. A number of genes that have been shown to have links with inherited forms of PD encode mitochondrial proteins or proteins implicated in mitochondrial dysfunction, supporting the central involvement of mitochondria in PD. This involvement is corroborated by reports that environmental toxins that inhibit the mitochondrial respiratory chain have been shown to be associated with PD. This paper aims to illustrate the considerable body of evidence linking mitochondrial dysfunction with neuronal cell death in the substantia nigra pars compacta (SNpc) of PD patients and to highlight the important need for further research in this area

    IMPACT OF WATER RADIOLYSIS ON URANIUM DIOXIDE CORROSION

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    International audienc

    Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids

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    Ionic liquids are salts used in a variety of industrial processes, and being relatively non-volatile, are proposed as environmentally-friendly replacements for existing volatile liquids. Methylimidazolium ionic liquids resist complete degradation in the environment, likely because the imidazolium moiety does not exist naturally in biological systems. However, there is limited data available regarding their mammalian effects in vivo. This study aimed to examine the effects of exposing mice separately to 2 different methylimidazolium ionic liquids (BMI and M8OI) through their addition to drinking water. Potential effects on key target organs-the liver and kidney-were examined, as well as the gut microbiome. Adult male mice were exposed to drinking water containing ionic liquids at a concentration of 440 mg/L for 18 weeks prior to examination of tissues, serum, urine and the gut microbiome. Histopathology was performed on tissues and clinical chemistry on serum for biomarkers of hepatic and renal injury. Bacterial DNA was isolated from the gut contents and subjected to targeted 16S rRNA sequencing. Mild hepatic and renal effects were limited to glycogen depletion and mild degenerative changes respectively. No hepatic or renal adverse effects were observed. In contrast, ionic liquid exposure altered gut microbial composition but not overall alpha diversity. Proportional abundance of Lachnospiraceae, Clostridia and Coriobacteriaceae spp. were significantly greater in ionic liquid-exposed mice, as were predicted KEGG functional pathways associated with xenobiotic and amino acid metabolism. Exposure to ionic liquids via drinking water therefore resulted in marked changes in the gut microbiome in mice prior to any overt pathological effects in target organs. Ionic liquids may be an emerging risk to health through their potential effects on the gut microbiome, which is implicated in the causes and/or severity of an array of chronic disease in humans

    Alpha localized radiolysis and corrosion mechanisms at the iron/water interface: Role of molecular species

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    This paper is devoted to the iron corrosion phenomena induced by the α (4He2+) water radiolysis species studied in conjunction with the production/consumption of H2 at the solid/solution interface. On one hand, the solid surface is characterized during the 4He2+ ions irradiation by in situ Raman spectroscopy; on another hand, the H2 gas produced by the water radiolysis is monitored by ex situ gas measurements. The 4He2+ ions irradiation experiments are provided either by the CEMHTI (E = 5.0 MeV) either by the ARRONAX (E = 64.7 MeV) cyclotron facilities. The iron corrosion occurs only under irradiation and can be slowed down by H2 reductive atmosphere. Pure iron and carbon steel solids are studied in order to show two distinct behaviors of these surfaces vs. the 4He2+ ions water irradiation: the corrosion products identified are the magnetite phase (Fe(II)Fe(III)2O4) correlated to an H2 consumption for pure iron and the lepidocrocite phase (γ-Fe(III)OOH) correlated to an H2 production for carbon steel sample. This paper underlined the correlation between the iron corrosion products formation onto the solid surface and the H2 production/consumption mechanisms. H2O2 species is considered as the single water radiolytic species involved into the corrosion reaction at the solid surface with an essential role in the oxidation reaction of the iron surface. We propose to bring some light to these mechanisms, in particular the H2 and H2O2 roles, by the in situ Raman spectroscopy during and after the 4He2+ ions beam irradiation. This in situ experiment avoids the evolution of the solid surface, in particular phases which are reactive to the oxidation processing

    The role of diatom resting spores in pelagic–benthic coupling in the Southern Ocean

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    Natural iron fertilization downstream of Southern Ocean island plateaus supports large phytoplankton blooms and promotes carbon export from the mixed layer. In addition to sequestering atmospheric CO2, the biological carbon pump also supplies organic matter (OM) to deep-ocean ecosystems. Although the total flux of OM arriving at the seafloor sets the energy input to the system, the chemical nature of OM is also of significance. However, a quantitative framework linking ecological flux vectors to OM composition is currently lacking. In the present study we report the lipid composition of export fluxes collected by five moored sediment traps deployed in contrasting productivity regimes of Southern Ocean island systems (Kerguelen, Crozet and South Georgia) and compile them with quantitative data on diatom and faecal pellet fluxes. At the three naturally iron-fertilized sites, the relative contribution of labile lipids (mono- and polyunsaturated fatty acids, unsaturated fatty alcohols) is 2–4 times higher than at low productivity sites. There is a strong attenuation of labile components as a function of depth, irrespective of productivity. The three island systems also display regional characteristics in lipid export. An enrichment of zooplankton dietary sterols, such as C27Δ5, at South Georgia is consistent with high zooplankton and krill biomass in the region and the importance of faecal pellets to particulate organic carbon (POC) flux. There is a strong association of diatom resting spore fluxes that dominate productive flux regimes with energy-rich unsaturated fatty acids. At the Kerguelen Plateau we provide a statistical framework to link seasonal variation in ecological flux vectors and lipid composition over a complete annual cycle. Our analyses demonstrate that ecological processes in the upper ocean, e.g. resting spore formation and grazing, not only impact the magnitude and stoichiometry of the Southern Ocean biological pump, but also regulate the composition of exported OM and the nature of pelagic–benthic coupling
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