Trombopenija v processe ljabliaza

A description of two cases of haemorrhagic diathesis in children caused by thrombocytopenia in the course of lambliosis. In children affected with various forms of haemorrhagic diatheses a strikingly high percentage constitute cases caused by quantitative and functional disturbances of thrombocytes. Acquired, secondary thrombocytopenia may develop in the course of infectious diseases, leucaemia, as the result of post-drug allergy or toxic injuries and as consequence of autoimmunization. Such parasites as ascaris, Trichuris trichiura can also cause thrombocytopenia. In the present cases no other cause could be established except the presence of Lamblia intestinalis. Therefore it seems plausible that solely they could be the cause of the injury of the coagulation system of the blood

Cutis laxa with growth and developmental delay, wrinkly skin syndrome and gerodermia osteodysplastica: a report of two unrelated patients and a literature review

Two unrelated patients of different sexes are described, both presenting with congenital redundant skin (cutis laxa), growth deficiency, mental retardation and bone dystrophy. Parental consanguinity in both families and a more pronounced severity of the neurological disease in the male patient were present. Both patients were diagnosed in infancy as having De Barsy syndrome, but clinical follow-up revealed that the clinical picture was compatible with the diagnosis of cutis laxa with growth and developmental delay (CLGDD), gerodermia osteodysplastica (GO) and wrinkly-skin syndrome (WWS). It has recently been suggested that cutis laxa with growth and developmental delay, gerodermia osteodysplastica and wrinkly skin syndrome are the same condition. A review concerning this diagnosis is also presented