Optical Camera with high temporal resolution to search for transients in the wide field

The wide field optical camera with high temporal resolution for the continuous monitoring of the sky in order to catch the initial stages of GRBs is described.Comment: 4 pages, 4 figures. To be published in "Il Nuovo Cimento", Proceedings of the 4th Rome Workshop on Gamma-Ray Bursts in the Afterglow Era, eds. L. Piro, L. Amati, S. Covino, B. Gendr

Pulsed voltage cold atmospheric plasma jet and gold nanoparticles enhance cytotoxic anticancer effect

Efficient and biologically safe mode of cold atmospheric plasma jet (CAPJ) is crucial for the development of CAPJ-based anticancer therapy. In the experiment and numerical simulations, by changing the pulse duration of a positive-pulsed voltage, we found the optimal CAPJ mode with regular streamer propagation. CAPJ regimes with a maximum discharge current at a temperature T<42 C substantially suppressed the viability of cancer cells. To enhance cell killing, gold nanoparticles (NPs) were added to the cells before and after the CAPJ exposure. Combination of CAPJ, generated with positive pulsed voltage, and gold nanoparticles decreased viability of NCI-H23 epithelial-like lung adenocarcinoma, A549 lung adenocarcinoma, BrCCh4e-134 breast adenocarcinoma and uMel1 uveal melanoma cells. Polyethylene glycol-modified nanoparticles with attached fluorescent label were used to visualize the uptake of NPs. We demonstrated that NPs efficiently entered the cells when were added to the cells just before CAPJ exposure or up to two hours afterwards. The efficiency ofNPs penetration into cells positively correlated with the induced cytotoxic effect: it was maximal when NPs was added to cells right before or immediately after CAPJ exposure. Summarizing, the treatment with optimal CAPJ modes in combination with modified NPs, bearing the cancer-addressed molecules and therapeutics may be next strategy of strengthening the CAPJ-based antitumor approaches.Comment: 19 pages, 8 figures, submitted to Journal of Physics D: Applied Physics The research was funded by Russian Science Foundation grant number 22-49-08003. The research on uMel1 cells cultivation was funded by Russian Science Foundation grant number 23-14-0028

Corrosion of diffusion zinc coatings in sodium chloride solutions

Diffusion galvanizing is widely used in the pipe industry for coating the threaded surface of pipe couplings, protecting water and gas pipelines, and other metal products. Diffusion coatings have a number of advantages over other types of zinc coatings. In this work, electrochemical and gravimetric methods are used to study the corrosion behavior of diffusion zinc coatings in sodium chloride solutions. The corrosion rate depends non-linearly on the thickness of the coating. At the initial stages, the corrosion rate of coatings depends on the structure of the phases on the surface, and with an increase in the holding time, the corrosion rate depends to a greater extent on the properties of the products formed during the corrosion process. Films of corrosion products of diffusion zinc coatings consist of zinc oxide/hydroxide and basic zinc salts, while the composition of the film changes with increasing coating thickness

Application of bent crystals at IHEP 70-GeV accelerator to enhance the efficiency of its usage

Bent crystal was extracting 70-GeV protons with average intensity 4*10^11 (as measured in external beamline) per spill of 1.6 s duration, in parallel to the simultaneous work of two internal targets in the accelerator ring. An additional crystal, placed in the external beamline, was deflecting a small part of the extracted beam with intensity 10^7 protons toward another physics experiment. Crystal-extracted beam had a typical size of 4 mm by 4 mm fwhm at the end of the external beamline. Measurements for the extraction efficiency and other characteristics at the simultaneous work of four experimental set-ups are presented. With crystal working in the above-said regime during one month, no degradation of channeling was observed. The studies of extraction efficiency have been continued with new crystals.Comment: 6pp. Presented at EPAC 200

Progress in crystal extraction and collimation

Recent IHEP Protvino experiments show efficiencies of crystal-assisted slow extraction and collimation of 85.3+-2.8%, at the intensities of the channeled beam on the order of 10^12 proton per spill of 2 s duration. The obtained experimental data well follows the theory predictions. We compare the measurements against theory and outline the theoretical potential for further improvement in the efficiency of the technique. This success is important for the efficient use of IHEP accelerator and for implementation of crystal-assisted collimation at RHIC and slow extraction from AGS onto E952, now in preparation. Future applications, spanning in the energy from order of 1 GeV (scraping in SNS, slow extraction from COSY and medical accelerators) to order of 1 TeV and beyond (scraping in Tevatron, LHC, VLHC), can benefit from these studies.Comment: 7pp. Presented at HEACC 2001 (Tsukuba, March 25-30

FAVOR (FAst Variability Optical Registration) -- A Two-telescope Complex for Detection and Investigation of Short Optical Transients

An astronomical complex intended to detect optical transients (OTs) in a wide field and follow them up with high time resolution investigation is described.Comment: 4 pages, 3 figures. To be published in "Il Nuovo Cimento", Proceedings of the 4th Rome Workshop on Gamma-Ray Bursts in the Afterglow Era, eds. L. Piro, L. Amati, S. Covino, B. Gendr

The Investigations Of Beam Extraction And Collimation At U-70 Proton Synchrotron Of IHEP By Using Short Silicon Crystals

The new results of using short (2-4mm) bent crystals for extraction and collimation of proton beam at IHEP 70 Gev proton synchrotron are reported. A broad range of energies from 6 to 65 GeV has been studied in the same crystal collimation set-up. The efficiency of extraction more than 85% and intensity more than 10E12 were obtained by using crystal with the length 2-mm and the angle 1 mrad. The new regime of extraction is applied now at the accelerator to deliver the beam for different experimental setups within the range of intensity 10E7-10E12ppp.Comment: Presented at EPAC 2002 (Paris, June 3-7), 3p