215 research outputs found

    Internal jugular vein thrombosis presenting as a painful neck mass due to a spontaneous dislocated subclavian port catheter as long-term complication: a case report

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    Central venous access devices are extensively used for long-term chemotherapy and parenteral nutrition. However, there are some possible immediate, early, and late complications related to the implantation technique, care, and maintenance. We present the uncommon occurrence of a thrombosis of the internal jugular vein due to a spontaneous migration of a Port-A-Cath catheter into the ipsilateral internal jugular vein as a delayed complication of a central venous access catheter implanted for chemotherapy delivery. A review of the literature is given, and the factors responsible for this unusual complication will be discussed

    A civilian perspective on ballistic trauma and gunshot injuries

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    <p>Abstract</p> <p>Background</p> <p>Gun violence is on the rise in some European countries, however most of the literature on gunshot injuries pertains to military weaponry and is difficult to apply to civilians, due to dissimilarities in wound contamination and wounding potential of firearms and ammunition. Gunshot injuries in civilians have more focal injury patterns and should be considered distinct entities.</p> <p>Methods</p> <p>A search of the National Library of Medicine and the National Institutes of Health MEDLINE database was performed using PubMed.</p> <p>Results</p> <p>Craniocerebral gunshot injuries are often lethal, especially after suicide attempts. The treatment of non space consuming haematomas and the indications for invasive pressure measurement are controversial. Civilian gunshot injuries to the torso mostly intend to kill; however for those patients who do not die at the scene and are hemodynamically stable, insertion of a chest tube is usually the only required procedure for the majority of penetrating chest injuries. In penetrating abdominal injuries there is a trend towards non-operative care, provided that the patient is hemodynamically stable. Spinal gunshots can also often be treated without operation. Gunshot injuries of the extremities are rarely life-threatening but can be associated with severe morbidity.</p> <p>With the exception of craniocerebral, bowel, articular, or severe soft tissue injury, the use of antibiotics is controversial and may depend on the surgeon's preference.</p> <p>Conclusion</p> <p>The treatment strategy for patients with gunshot injuries to the torso mostly depends on the hemodynamic status of the patient. Whereas hemodynamically unstable patients require immediate operative measures like thoracotomy or laparotomy, hemodynamically stable patients might be treated with minor surgical procedures (e.g. chest tube) or even conservatively.</p

    The Snail genes as inducers of cell movement and survival: implications in development and cancer

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    11 pages, 5 figures.-- PMID: 15983400 [PubMed].-- Printed version published Jul 2005.Full-text version available Open Access at the journal site.The functions of the Snail family of zinc-finger transcription factors are essential during embryonic development. One of their best-known functions is to induce epithelial to mesenchymal transitions (EMTs), which convert epithelial cells into migratory mesenchymal cells. In recent years, many orthologues of the Snail family have been identified throughout the animal kingdom, and their study is providing new clues about the EMT-dependent and -independent functions of Snail proteins. Here, we discuss these functions and how they influence cell behaviour during development and during diseases such as metastatic cancer. From these findings, we propose that Snail genes act primarily as survival factors and inducers of cell movement, rather than as inducers of EMT or cell fate.We are grateful to all members of M. A. Nieto’s laboratory for encouraging discussions. Work in the laboratory is mainly supported by grants from the Spanish Ministry of Education and Science. A.B.-G. is a researcher of the RamΓ³n y Cajal Programme (MEC).Peer reviewe

    ВлияниС рСлаксационной прочности Π·Π΅Ρ€Π΅Π½ ΠΈ ΠΌΠ΅ΠΆΠ·Π΅Ρ€Π΅Π½Π½Ρ‹Ρ… Π³Ρ€Π°Π½ΠΈΡ† Π² ΠΊΠΎΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… сталях Π½Π° Ρ€Π°Π±ΠΎΡ‚ΠΎΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡ‚ΡŒ повСрхностСй Π½Π°Π³Ρ€Π΅Π²Π°

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    ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½Ρ‹ ΡΠΊΡΠΏΠ΅Ρ€ΠΈΠΌΠ΅Π½Ρ‚Π°Π»ΡŒΠ½Ρ‹Π΅ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ исслСдований отСчСствСнной Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠΈ аустСнитной Ρ…Ρ€ΠΎΠΌΠΎΠΌΠ°Ρ€Π³Π°Π½Ρ†Π΅Π²ΠΎΠΉ стали 10Π₯13Π“12Π‘2Н2Π”2Π‘ (Π”ΠΈ-59). На основС Ρ€Π΅Π½Ρ‚Π³Π΅Π½ΠΎΠΌΠ΅Ρ‚Ρ€ΠΈΠΈ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, Ρ‡Ρ‚ΠΎ осцилляции Π²Π½ΡƒΡ‚Ρ€Π΅Π½Π½ΠΈΡ… напряТСний ΠΏΡ€ΠΈ цикличСском ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΈ Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Ρ‹, ΡΠΎΠΏΡ€ΠΎΠ²ΠΎΠΆΠ΄Π°ΡŽΡ‰ΠΈΠ΅ΡΡ процСссами рСлаксации ΠΏΡ€ΠΈ ΠΏΠ΅Ρ€Π΅ΠΌΠ΅Π½Π΅ Π·Π½Π°ΠΊΠ°, ΠΎΠΊΠ°ΠΆΡƒΡ‚ сущСствСнноС влияниС Π½Π° прочностныС характСристики ΠΈ послуТат ΠΏΡ€ΠΈΡ‡ΠΈΠ½ΠΎΠΉ тСрмичСской усталости ΠΌΠ΅Ρ‚Π°Π»Π»Π°, Π° ΠΊΡ€ΠΈΡ‚Π΅Ρ€ΠΈΠΈ рСлаксации напряТСний ΠΈ условия ΠΈΡ… протСкания станут ΠΎΠΏΡ€Π΅Π΄Π΅Π»ΡΡŽΡ‰ΠΈΠΌΠΈ для Ρ€Π°Π±ΠΎΡ‚Ρ‹ ΠΌΠ΅Ρ‚Π°Π»Π»Π° ΠΏΡ€ΠΈ высоких Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Π°Ρ… эксплуатации. ΠžΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½Π½Ρ‹ΠΉ Π²Ρ‹Π±ΠΎΡ€ Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Ρ‹ эксплуатации, сущСствСнно ΠΏΠΎΠ²Ρ‹ΡˆΠ°ΡŽΡ‰ΠΈΠΉ Ρ€Π΅Π»Π°ΠΊΡΠ°Ρ†ΠΈΠΎΠ½Π½ΡƒΡŽ ΠΏΡ€ΠΎΡ‡Π½ΠΎΡΡ‚ΡŒ Π·Π΅Ρ€Π΅Π½ ΠΈ ΠΌΠ΅ΠΆΠ·Π΅Ρ€Π΅Π½Π½Ρ‹Ρ… Π³Ρ€Π°Π½ΠΈΡ† сплава, являСтся основой продлСния рСсурса работоспособности

    ΠœΠΈΠ½ΠΈΠΌΠ°Π»ΡŒΠ½Ρ‹ΠΉ сток Π˜Ρ€Ρ‚Ρ‹ΡˆΠ° Π² Ρ€Π°Π²Π½ΠΈΠ½Π½ΠΎΠΉ части бассСйна Π½Π° Ρ‚Π΅Ρ€Ρ€ΠΈΡ‚ΠΎΡ€ΠΈΠΈ РСспублики ΠšΠ°Π·Π°Ρ…ΡΡ‚Π°Π½ Π² условиях Π°Π½Ρ‚Ρ€ΠΎΠΏΠΎΠ³Π΅Π½Π½ΠΎΠΉ Π½Π°Π³Ρ€ΡƒΠ·ΠΊΠΈ

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    Π’ Π³ΠΈΠ΄Ρ€ΠΎΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠ΅ России Π˜Ρ€Ρ‚Ρ‹Ρˆ, ΠΊΠ°ΠΊ трансграничная Ρ€Π΅ΠΊΠ°, являСтся ΠΏΡ€Π΅Π΄ΠΌΠ΅Ρ‚ΠΎΠΌ ΠΏΠ΅Ρ€Π΅Π³ΠΎΠ²ΠΎΡ€ΠΎΠ² Π½Π° Ρ€Π°Π·Π½Ρ‹Ρ… уровнях ΠΏΠΎ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠ΅ совмСстного использования Π²ΠΎΠ΄Π½Ρ‹Ρ… рСсурсов с РСспубликой ΠšΠ°Π·Π°Ρ…ΡΡ‚Π°Π½ ΠΈ ΠšΠΈΡ‚Π°Π΅ΠΌ. Π’ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Π΅ Π²Π²ΠΎΠ΄Π° Π² строй Π’Π΅Ρ€Ρ…Π½Π΅-Π˜Ρ€Ρ‚Ρ‹ΡˆΡΠΊΠΎΠ³ΠΎ каскада Π²ΠΎΠ΄ΠΎΡ…Ρ€Π°Π½ΠΈΠ»ΠΈΡ‰ Π² Ρ€Π°Π²Π½ΠΈΠ½Π½ΠΎΠΉ части бассСйна Π˜Ρ€Ρ‚Ρ‹ΡˆΠ° прослСТиваСтся ΡƒΡ…ΡƒΠ΄ΡˆΠ΅Π½ΠΈΠ΅ экологичСского состояния, Π² частности ΠΏΠΎΠΉΠΌΠ΅Π½Π½Ρ‹Ρ… зСмСль, ΠΈΠΌΠ΅ΡŽΡ‰ΠΈΡ… ΠΎΠ³Ρ€ΠΎΠΌΠ½ΠΎΠ΅ Π·Π½Π°Ρ‡Π΅Π½ΠΈΠ΅ Π² качСствС источника ΠΊΠΎΡ€ΠΌΠΎΠ²Ρ‹Ρ… рСсурсов для ΡΠ΅Π»ΡŒΡΠΊΠΎΡ…ΠΎΠ·ΡΠΉΡΡ‚Π²Π΅Π½Π½ΠΎΠ³ΠΎ производства. ΠŸΠΎΡΡ‚ΠΎΠΌΡƒ Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹ΠΌ являСтся Π°Π½Π°Π»ΠΈΠ· соврСмСнного состояния ΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Ρ… характСристик гидрологичСского Ρ€Π΅ΠΆΠΈΠΌΠ° Ρ€Π΅ΠΊΠΈ, Π² Ρ‚ΠΎΠΌ числС минимального стока. ЦСль Ρ€Π°Π±ΠΎΡ‚Ρ‹: выявлСниС ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ Π²ΠΎΠ΄Π½ΠΎΠ³ΠΎ Ρ€Π΅ΠΆΠΈΠΌΠ° ΠΈ минимального стока Π²ΠΎΠ΄Ρ‹ Ρ€. Π˜Ρ€Ρ‚Ρ‹Ρˆ Π½Π° Ρ€Π°Π²Π½ΠΈΠ½Π½ΠΎΠΉ части водосбора (Π² ΠΏΡ€Π΅Π΄Π΅Π»Π°Ρ… РСспублики ΠšΠ°Π·Π°Ρ…ΡΡ‚Π°Π½). ΠœΠ΅Ρ‚ΠΎΠ΄Ρ‹ исслСдования. Π’ Ρ€Π°Π±ΠΎΡ‚Π΅ примСнялся Π³Π΅ΠΎΠ³Ρ€Π°Ρ„ΠΎ-гидрологичСский ΠΌΠ΅Ρ‚ΠΎΠ΄ Π°Π½Π°Π»ΠΈΠ·Π° ΠΌΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»ΠΎΠ² наблюдСний Π·Π° стоком Ρ€. Π˜Ρ€Ρ‚Ρ‹Ρˆ Π² створС ΠΏ. БСмиярка, располоТСнном Π½Π° Ρ€Π΅ΠΊΠ΅ нСпосрСдствСнно Π½ΠΈΠΆΠ΅ ΠΏΠΎ Ρ‚Π΅Ρ‡Π΅Π½ΠΈΡŽ ΠΎΡ‚ каскада Π²ΠΎΠ΄ΠΎΡ…Ρ€Π°Π½ΠΈΠ»ΠΈΡ‰, Π·Π° Π΄Π²Π° Π²Ρ€Π΅ΠΌΠ΅Π½Π½Ρ‹Ρ… ΠΈΠ½Ρ‚Π΅Ρ€Π²Π°Π»Π°: Π² СстСствСнных (1935-1959 Π³Π³.) ΠΈ Π² Π·Π°Ρ€Π΅Π³ΡƒΠ»ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹Ρ… (1967-2010 Π³Π³.) условиях. Использовались ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹ матСматичСской статистики для ΠΏΡ€ΠΎΠ²Π΅Ρ€ΠΊΠΈ гидрологичСских рядов Π½Π° ΠΎΠ΄Π½ΠΎΡ€ΠΎΠ΄Π½ΠΎΡΡ‚ΡŒ (ΠΊΡ€ΠΈΡ‚Π΅Ρ€ΠΈΠΈ Π€ΠΈΡˆΠ΅Ρ€Π° ΠΈ Π‘Ρ‚ΡŒΡŽΠ΄Π΅Π½Ρ‚Π°) ΠΈ ΡΠ»ΡƒΡ‡Π°ΠΉΠ½ΠΎΡΡ‚ΡŒ ΠΏΠΎ парамСтричСским ΠΈ нСпарамСтричСским критСриям. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. Показано, Ρ‡Ρ‚ΠΎ Ρ€Π΅Π³ΡƒΠ»ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ стока Π²ΠΎΠ΄Ρ‹ Π’Π΅Ρ€Ρ…Π½Π΅-Π˜Ρ€Ρ‚Ρ‹ΡˆΡΠΊΠΈΠΌ каскадом Π²ΠΎΠ΄ΠΎΡ…Ρ€Π°Π½ΠΈΠ»ΠΈΡ‰ ΠΏΡ€ΠΈΠ²Π΅Π»ΠΎ ΠΊ сущСствСнному ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΡŽ Π»Π΅Ρ‚Π½Π΅Π³ΠΎ минимального срСднСмСсячного расхода (Π½Π° 22 %), ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΡŽ Π·ΠΈΠΌΠ½Π΅Π³ΠΎ минимального расхода (Π½Π° 78 %), ΠΏΠ΅Ρ€Π΅Ρ€Π°ΡΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΡŽ объСмов стока Ρ€. Π˜Ρ€Ρ‚Ρ‹Ρˆ ΠΌΠ΅ΠΆΠ΄Ρƒ Π»Π΅Ρ‚Π½ΠΈΠΌ (ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΠ΅ Π½Π° 38 %) ΠΈ Π·ΠΈΠΌΠ½ΠΈΠΌ (ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠ΅ Π½Π° 70 %) сСзонами, ΠΈ, ΠΊΠ°ΠΊ слСдствиС, ΠΊ ΡƒΡ…ΡƒΠ΄ΡˆΠ΅Π½ΠΈΡŽ Π³ΠΈΠ΄Ρ€ΠΎ-экологичСского состояния ΠΏΠΎΠΉΠΌΠ΅Π½Π½Ρ‹Ρ… зСмСль. Π’ качСствС Π±Π°Π·Ρ‹ сравнСния использовались ΡΠΎΠΎΡ‚Π²Π΅Ρ‚ΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΠ΅ характСристики стока Π² СстСствСнных условиях.In Russian hydropolitics, the Irtysh as the transboundary river is the subject of different level negotiations on the issue of shared use of water resources with the Republic of Kazakhstan and China. In the result of putting in operation of the Upper-Irtysh multireservoir cascade the deterioration of environmental condition, particularly, in a floodplain which has major significance as the source of feed supplies for agricultural production, is observed in the flat part of the Irtysh basin. Therefore, it is important to analyze current condition and changes of different characteristics of hydrological regime of the river, and specifically the minimum flow. The aim of the researchis to indicate the changes of water flow regime and minimum water flow rates in the Irtysh River in the flat part of its basin (in the Republic of Kazakhstan). Research methods. The authors have applies hydrological and geographical approach to analyze standard observational data on the Irtysh flow in the cross section at Semiyarka village - a water level gauge station located directly downstream the multireservoir cascade during two time periods: in natural (1935-1959) and regulated (1967-2010) conditions. Statistical methods were applied: testing homogeneity of the means and variances using the Student t-test and the Fisher F-test, and trend significance using parametric and non-parametric criteria. Results. It is shown that water flow regulation by the Upper-Irtysh multireservoir cascade resulted in significant decrease of minimum summer monthly river discharge (by 22 %), increase of minimum winter river discharge (by 78 %), redistribution of the Irtysh flow between summer (decrease by 38 %) and winter (increase by 70 %) seasons, and, as a consequence, in deterioration of hydrological and environmental condition of the floodplain. Corresponding flow characteristics under natural conditions were used as the base for comparison

    ΠŸΡ€ΠΎΠ΅ΠΊΡ‚ ΠΏΠ»Π°Π½ΠΈΡ€ΠΎΠ²ΠΊΠΈ ΠΈ мСТСвания Ρ‚Π΅Ρ€Ρ€ΠΈΡ‚ΠΎΡ€ΠΈΠΈ ΠΊΠ²Π°Ρ€Ρ‚Π°Π»Π° Π² производствСнно-Π΄Π΅Π»ΠΎΠ²ΠΎΠΉ Π·ΠΎΠ½Π΅ Π³. Вомска

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    ΠŸΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠ° ΠΏΡ€ΠΎΠ΅ΠΊΡ‚Π° мСТСвания осущСствляСтся ΠΏΡ€ΠΈΠΌΠ΅Π½ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ ΠΊ Ρ‚Π΅Ρ€Ρ€ΠΈΡ‚ΠΎΡ€ΠΈΠΈ, располоТСнной Π² Π³Ρ€Π°Π½ΠΈΡ†Π°Ρ… элСмСнта ΠΏΠ»Π°Π½ΠΈΡ€ΠΎΠ²ΠΎΡ‡Π½ΠΎΠΉ структуры – Π½Π΅ΠΆΠΈΠ»ΠΎΠ³ΠΎ ΠΊΠ²Π°Ρ€Ρ‚Π°Π»Π°, ΠΎΠ³Ρ€Π°Π½ΠΈΡ‡Π΅Π½Π½ΠΎΠ³ΠΎ проспСктом ΠšΠΈΡ€ΠΎΠ²Π°, ΡƒΠ»ΠΈΡ†Π°ΠΌΠΈ КиСвская, Усова, Артёма. Π“Ρ€Π°Π½ΠΈΡ†Ρ‹ ΠΊΠ²Π°Ρ€Ρ‚Π°Π»Π° ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ Π³Π΅Π½Π΅Ρ€Π°Π»ΡŒΠ½Ρ‹ΠΌ ΠΏΠ»Π°Π½ΠΎΠΌ Π³ΠΎΡ€ΠΎΠ΄Π° Вомска, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΏΡ€Π°Π²ΠΈΠ»Π°ΠΌΠΈ зСмлСпользования ΠΈ застройки Π³ΠΎΡ€ΠΎΠ΄Π° Вомска. ΠŸΡ€ΠΎΠ΅ΠΊΡ‚ мСТСвания ΠΊΠ²Π°Ρ€Ρ‚Π°Π»Π° подготавливаСтся Π½Π° основС ΠΏΡ€ΠΎΠ΅ΠΊΡ‚Π° ΠΏΠ»Π°Π½ΠΈΡ€ΠΎΠ²ΠΊΠΈ Π΄Π°Π½Π½ΠΎΠΉ Ρ‚Π΅Ρ€Ρ€ΠΈΡ‚ΠΎΡ€ΠΈΠΈ Π² цСлях установлСния Π³Ρ€Π°Π½ΠΈΡ† Π·Π΅ΠΌΠ΅Π»ΡŒΠ½Ρ‹Ρ… участков ΠΈ содСрТит Π³Ρ€Π°Ρ„ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ ΠΈ Ρ‚Π΅ΠΊΡΡ‚ΠΎΠ²ΡƒΡŽ части. ОснованиСм для ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠΈ ΠΏΡ€ΠΎΠ΅ΠΊΡ‚Π° мСТСвания являСтся постановлСниС администрации Π“ΠΎΡ€ΠΎΠ΄Π° Вомска ΠΎΡ‚ 27.03.2017 Π³. β„–275-Π·.The boundary-setting plan is developed to the Tomsk’s non-residental quarter. An element of planning structure has its borders submitted by Kirova avenue, Kievskaya, Usova and Artyoma streets. Borders of quarter are defined by the city master plan and rules of land use and building of the city of Tomsk. The boundary-setting plan of quarter is prepared on the basis of the draft area plan of this territory for the purpose of land parcels borders establishment. The project consists of a graphic part and the text explanation. The basis for preparation of the project is the resolution of city administration of Tomsk

    Analysis of actual models of cooperation in regional innovative system

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    The article deals with models of collaboration. It is vital to note that there is no single model (example) for networking in regional innovative system, but most of existing models based on Triple Helix Model. In article also are described the common type of cooperation in network structure and detailed their main characteristics
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