215 research outputs found
Internal jugular vein thrombosis presenting as a painful neck mass due to a spontaneous dislocated subclavian port catheter as long-term complication: a case report
Central venous access devices are extensively used for long-term chemotherapy and parenteral nutrition. However, there are some possible immediate, early, and late complications related to the implantation technique, care, and maintenance. We present the uncommon occurrence of a thrombosis of the internal jugular vein due to a spontaneous migration of a Port-A-Cath catheter into the ipsilateral internal jugular vein as a delayed complication of a central venous access catheter implanted for chemotherapy delivery. A review of the literature is given, and the factors responsible for this unusual complication will be discussed
A civilian perspective on ballistic trauma and gunshot injuries
<p>Abstract</p> <p>Background</p> <p>Gun violence is on the rise in some European countries, however most of the literature on gunshot injuries pertains to military weaponry and is difficult to apply to civilians, due to dissimilarities in wound contamination and wounding potential of firearms and ammunition. Gunshot injuries in civilians have more focal injury patterns and should be considered distinct entities.</p> <p>Methods</p> <p>A search of the National Library of Medicine and the National Institutes of Health MEDLINE database was performed using PubMed.</p> <p>Results</p> <p>Craniocerebral gunshot injuries are often lethal, especially after suicide attempts. The treatment of non space consuming haematomas and the indications for invasive pressure measurement are controversial. Civilian gunshot injuries to the torso mostly intend to kill; however for those patients who do not die at the scene and are hemodynamically stable, insertion of a chest tube is usually the only required procedure for the majority of penetrating chest injuries. In penetrating abdominal injuries there is a trend towards non-operative care, provided that the patient is hemodynamically stable. Spinal gunshots can also often be treated without operation. Gunshot injuries of the extremities are rarely life-threatening but can be associated with severe morbidity.</p> <p>With the exception of craniocerebral, bowel, articular, or severe soft tissue injury, the use of antibiotics is controversial and may depend on the surgeon's preference.</p> <p>Conclusion</p> <p>The treatment strategy for patients with gunshot injuries to the torso mostly depends on the hemodynamic status of the patient. Whereas hemodynamically unstable patients require immediate operative measures like thoracotomy or laparotomy, hemodynamically stable patients might be treated with minor surgical procedures (e.g. chest tube) or even conservatively.</p
The Snail genes as inducers of cell movement and survival: implications in development and cancer
11 pages, 5 figures.-- PMID: 15983400 [PubMed].-- Printed version published Jul 2005.Full-text version available Open Access at the journal site.The functions of the Snail family of zinc-finger transcription factors are essential during embryonic development. One of their best-known functions is to induce epithelial to mesenchymal transitions (EMTs), which convert epithelial cells into migratory mesenchymal cells. In recent years, many orthologues of the Snail family have been identified throughout the animal kingdom, and their study is providing new clues about the EMT-dependent and -independent functions of Snail proteins. Here, we discuss these functions and how they influence cell behaviour during development and during diseases such as metastatic cancer. From these findings, we propose that Snail genes act primarily as survival factors and inducers of cell movement, rather than as inducers of EMT or cell fate.We are grateful to all members of M. A. Nietoβs laboratory for encouraging discussions. Work in the laboratory is mainly supported by grants from the Spanish Ministry of Education and Science. A.B.-G. is a researcher of the RamΓ³n y Cajal Programme (MEC).Peer reviewe
ΠΠ»ΠΈΡΠ½ΠΈΠ΅ ΡΠ΅Π»Π°ΠΊΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΠΏΡΠΎΡΠ½ΠΎΡΡΠΈ Π·Π΅ΡΠ΅Π½ ΠΈ ΠΌΠ΅ΠΆΠ·Π΅ΡΠ΅Π½Π½ΡΡ Π³ΡΠ°Π½ΠΈΡ Π² ΠΊΠΎΡΠ΅Π»ΡΠ½ΡΡ ΡΡΠ°Π»ΡΡ Π½Π° ΡΠ°Π±ΠΎΡΠΎΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΡ ΠΏΠΎΠ²Π΅ΡΡ Π½ΠΎΡΡΠ΅ΠΉ Π½Π°Π³ΡΠ΅Π²Π°
ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ ΠΎΡΠ΅ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠΈ Π°ΡΡΡΠ΅Π½ΠΈΡΠ½ΠΎΠΉ Ρ
ΡΠΎΠΌΠΎΠΌΠ°ΡΠ³Π°Π½ΡΠ΅Π²ΠΎΠΉ ΡΡΠ°Π»ΠΈ 10Π₯13Π12Π‘2Π2Π2Π (ΠΠΈ-59). ΠΠ° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠ΅Π½ΡΠ³Π΅Π½ΠΎΠΌΠ΅ΡΡΠΈΠΈ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ ΠΎΡΡΠΈΠ»Π»ΡΡΠΈΠΈ Π²Π½ΡΡΡΠ΅Π½Π½ΠΈΡ
Π½Π°ΠΏΡΡΠΆΠ΅Π½ΠΈΠΉ ΠΏΡΠΈ ΡΠΈΠΊΠ»ΠΈΡΠ΅ΡΠΊΠΎΠΌ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΈ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΡ, ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π°ΡΡΠΈΠ΅ΡΡ ΠΏΡΠΎΡΠ΅ΡΡΠ°ΠΌΠΈ ΡΠ΅Π»Π°ΠΊΡΠ°ΡΠΈΠΈ ΠΏΡΠΈ ΠΏΠ΅ΡΠ΅ΠΌΠ΅Π½Π΅ Π·Π½Π°ΠΊΠ°, ΠΎΠΊΠ°ΠΆΡΡ ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠ΅ Π²Π»ΠΈΡΠ½ΠΈΠ΅ Π½Π° ΠΏΡΠΎΡΠ½ΠΎΡΡΠ½ΡΠ΅ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ ΠΈ ΠΏΠΎΡΠ»ΡΠΆΠ°Ρ ΠΏΡΠΈΡΠΈΠ½ΠΎΠΉ ΡΠ΅ΡΠΌΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΡΠ°Π»ΠΎΡΡΠΈ ΠΌΠ΅ΡΠ°Π»Π»Π°, Π° ΠΊΡΠΈΡΠ΅ΡΠΈΠΈ ΡΠ΅Π»Π°ΠΊΡΠ°ΡΠΈΠΈ Π½Π°ΠΏΡΡΠΆΠ΅Π½ΠΈΠΉ ΠΈ ΡΡΠ»ΠΎΠ²ΠΈΡ ΠΈΡ
ΠΏΡΠΎΡΠ΅ΠΊΠ°Π½ΠΈΡ ΡΡΠ°Π½ΡΡ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΡΡΠΈΠΌΠΈ Π΄Π»Ρ ΡΠ°Π±ΠΎΡΡ ΠΌΠ΅ΡΠ°Π»Π»Π° ΠΏΡΠΈ Π²ΡΡΠΎΠΊΠΈΡ
ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΠ°Ρ
ΡΠΊΡΠΏΠ»ΡΠ°ΡΠ°ΡΠΈΠΈ. ΠΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½Π½ΡΠΉ Π²ΡΠ±ΠΎΡ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΡ ΡΠΊΡΠΏΠ»ΡΠ°ΡΠ°ΡΠΈΠΈ, ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎ ΠΏΠΎΠ²ΡΡΠ°ΡΡΠΈΠΉ ΡΠ΅Π»Π°ΠΊΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ ΠΏΡΠΎΡΠ½ΠΎΡΡΡ Π·Π΅ΡΠ΅Π½ ΠΈ ΠΌΠ΅ΠΆΠ·Π΅ΡΠ΅Π½Π½ΡΡ
Π³ΡΠ°Π½ΠΈΡ ΡΠΏΠ»Π°Π²Π°, ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΡΠ½ΠΎΠ²ΠΎΠΉ ΠΏΡΠΎΠ΄Π»Π΅Π½ΠΈΡ ΡΠ΅ΡΡΡΡΠ° ΡΠ°Π±ΠΎΡΠΎΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠΈ
ΠΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΡΠΉ ΡΡΠΎΠΊ ΠΡΡΡΡΠ° Π² ΡΠ°Π²Π½ΠΈΠ½Π½ΠΎΠΉ ΡΠ°ΡΡΠΈ Π±Π°ΡΡΠ΅ΠΉΠ½Π° Π½Π° ΡΠ΅ΡΡΠΈΡΠΎΡΠΈΠΈ Π Π΅ΡΠΏΡΠ±Π»ΠΈΠΊΠΈ ΠΠ°Π·Π°Ρ ΡΡΠ°Π½ Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ Π°Π½ΡΡΠΎΠΏΠΎΠ³Π΅Π½Π½ΠΎΠΉ Π½Π°Π³ΡΡΠ·ΠΊΠΈ
Π Π³ΠΈΠ΄ΡΠΎΠΏΠΎΠ»ΠΈΡΠΈΠΊΠ΅ Π ΠΎΡΡΠΈΠΈ ΠΡΡΡΡ, ΠΊΠ°ΠΊ ΡΡΠ°Π½ΡΠ³ΡΠ°Π½ΠΈΡΠ½Π°Ρ ΡΠ΅ΠΊΠ°, ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΏΡΠ΅Π΄ΠΌΠ΅ΡΠΎΠΌ ΠΏΠ΅ΡΠ΅Π³ΠΎΠ²ΠΎΡΠΎΠ² Π½Π° ΡΠ°Π·Π½ΡΡ
ΡΡΠΎΠ²Π½ΡΡ
ΠΏΠΎ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ΅ ΡΠΎΠ²ΠΌΠ΅ΡΡΠ½ΠΎΠ³ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ Π²ΠΎΠ΄Π½ΡΡ
ΡΠ΅ΡΡΡΡΠΎΠ² Ρ Π Π΅ΡΠΏΡΠ±Π»ΠΈΠΊΠΎΠΉ ΠΠ°Π·Π°Ρ
ΡΡΠ°Π½ ΠΈ ΠΠΈΡΠ°Π΅ΠΌ. Π ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ Π²Π²ΠΎΠ΄Π° Π² ΡΡΡΠΎΠΉ ΠΠ΅ΡΡ
Π½Π΅-ΠΡΡΡΡΡΠΊΠΎΠ³ΠΎ ΠΊΠ°ΡΠΊΠ°Π΄Π° Π²ΠΎΠ΄ΠΎΡ
ΡΠ°Π½ΠΈΠ»ΠΈΡ Π² ΡΠ°Π²Π½ΠΈΠ½Π½ΠΎΠΉ ΡΠ°ΡΡΠΈ Π±Π°ΡΡΠ΅ΠΉΠ½Π° ΠΡΡΡΡΠ° ΠΏΡΠΎΡΠ»Π΅ΠΆΠΈΠ²Π°Π΅ΡΡΡ ΡΡ
ΡΠ΄ΡΠ΅Π½ΠΈΠ΅ ΡΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ, Π² ΡΠ°ΡΡΠ½ΠΎΡΡΠΈ ΠΏΠΎΠΉΠΌΠ΅Π½Π½ΡΡ
Π·Π΅ΠΌΠ΅Π»Ρ, ΠΈΠΌΠ΅ΡΡΠΈΡ
ΠΎΠ³ΡΠΎΠΌΠ½ΠΎΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅ Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠ° ΠΊΠΎΡΠΌΠΎΠ²ΡΡ
ΡΠ΅ΡΡΡΡΠΎΠ² Π΄Π»Ρ ΡΠ΅Π»ΡΡΠΊΠΎΡ
ΠΎΠ·ΡΠΉΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²Π°. ΠΠΎΡΡΠΎΠΌΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΠΌ ΡΠ²Π»ΡΠ΅ΡΡΡ Π°Π½Π°Π»ΠΈΠ· ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ ΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊ Π³ΠΈΠ΄ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ΅ΠΆΠΈΠΌΠ° ΡΠ΅ΠΊΠΈ, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΠΎΠΊΠ°. Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ: Π²ΡΡΠ²Π»Π΅Π½ΠΈΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ Π²ΠΎΠ΄Π½ΠΎΠ³ΠΎ ΡΠ΅ΠΆΠΈΠΌΠ° ΠΈ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΠΎΠΊΠ° Π²ΠΎΠ΄Ρ Ρ. ΠΡΡΡΡ Π½Π° ΡΠ°Π²Π½ΠΈΠ½Π½ΠΎΠΉ ΡΠ°ΡΡΠΈ Π²ΠΎΠ΄ΠΎΡΠ±ΠΎΡΠ° (Π² ΠΏΡΠ΅Π΄Π΅Π»Π°Ρ
Π Π΅ΡΠΏΡΠ±Π»ΠΈΠΊΠΈ ΠΠ°Π·Π°Ρ
ΡΡΠ°Π½). ΠΠ΅ΡΠΎΠ΄Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ. Π ΡΠ°Π±ΠΎΡΠ΅ ΠΏΡΠΈΠΌΠ΅Π½ΡΠ»ΡΡ Π³Π΅ΠΎΠ³ΡΠ°ΡΠΎ-Π³ΠΈΠ΄ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΉ ΠΌΠ΅ΡΠΎΠ΄ Π°Π½Π°Π»ΠΈΠ·Π° ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»ΠΎΠ² Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΠΉ Π·Π° ΡΡΠΎΠΊΠΎΠΌ Ρ. ΠΡΡΡΡ Π² ΡΡΠ²ΠΎΡΠ΅ ΠΏ. Π‘Π΅ΠΌΠΈΡΡΠΊΠ°, ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½Π½ΠΎΠΌ Π½Π° ΡΠ΅ΠΊΠ΅ Π½Π΅ΠΏΠΎΡΡΠ΅Π΄ΡΡΠ²Π΅Π½Π½ΠΎ Π½ΠΈΠΆΠ΅ ΠΏΠΎ ΡΠ΅ΡΠ΅Π½ΠΈΡ ΠΎΡ ΠΊΠ°ΡΠΊΠ°Π΄Π° Π²ΠΎΠ΄ΠΎΡ
ΡΠ°Π½ΠΈΠ»ΠΈΡ, Π·Π° Π΄Π²Π° Π²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
ΠΈΠ½ΡΠ΅ΡΠ²Π°Π»Π°: Π² Π΅ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
(1935-1959 Π³Π³.) ΠΈ Π² Π·Π°ΡΠ΅Π³ΡΠ»ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
(1967-2010 Π³Π³.) ΡΡΠ»ΠΎΠ²ΠΈΡΡ
. ΠΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈΡΡ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΌΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΠ°ΡΠΈΡΡΠΈΠΊΠΈ Π΄Π»Ρ ΠΏΡΠΎΠ²Π΅ΡΠΊΠΈ Π³ΠΈΠ΄ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΡΠ΄ΠΎΠ² Π½Π° ΠΎΠ΄Π½ΠΎΡΠΎΠ΄Π½ΠΎΡΡΡ (ΠΊΡΠΈΡΠ΅ΡΠΈΠΈ Π€ΠΈΡΠ΅ΡΠ° ΠΈ Π‘ΡΡΡΠ΄Π΅Π½ΡΠ°) ΠΈ ΡΠ»ΡΡΠ°ΠΉΠ½ΠΎΡΡΡ ΠΏΠΎ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΈ Π½Π΅ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΊΡΠΈΡΠ΅ΡΠΈΡΠΌ. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ ΡΠ΅Π³ΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΡΠΎΠΊΠ° Π²ΠΎΠ΄Ρ ΠΠ΅ΡΡ
Π½Π΅-ΠΡΡΡΡΡΠΊΠΈΠΌ ΠΊΠ°ΡΠΊΠ°Π΄ΠΎΠΌ Π²ΠΎΠ΄ΠΎΡ
ΡΠ°Π½ΠΈΠ»ΠΈΡ ΠΏΡΠΈΠ²Π΅Π»ΠΎ ΠΊ ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΌΡ ΡΠΌΠ΅Π½ΡΡΠ΅Π½ΠΈΡ Π»Π΅ΡΠ½Π΅Π³ΠΎ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ΅Π΄Π½Π΅ΠΌΠ΅ΡΡΡΠ½ΠΎΠ³ΠΎ ΡΠ°ΡΡ
ΠΎΠ΄Π° (Π½Π° 22 %), ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΡ Π·ΠΈΠΌΠ½Π΅Π³ΠΎ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ°ΡΡ
ΠΎΠ΄Π° (Π½Π° 78 %), ΠΏΠ΅ΡΠ΅ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΎΠ±ΡΠ΅ΠΌΠΎΠ² ΡΡΠΎΠΊΠ° Ρ. ΠΡΡΡΡ ΠΌΠ΅ΠΆΠ΄Ρ Π»Π΅ΡΠ½ΠΈΠΌ (ΡΠΌΠ΅Π½ΡΡΠ΅Π½ΠΈΠ΅ Π½Π° 38 %) ΠΈ Π·ΠΈΠΌΠ½ΠΈΠΌ (ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΠ΅ Π½Π° 70 %) ΡΠ΅Π·ΠΎΠ½Π°ΠΌΠΈ, ΠΈ, ΠΊΠ°ΠΊ ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠ΅, ΠΊ ΡΡ
ΡΠ΄ΡΠ΅Π½ΠΈΡ Π³ΠΈΠ΄ΡΠΎ-ΡΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ ΠΏΠΎΠΉΠΌΠ΅Π½Π½ΡΡ
Π·Π΅ΠΌΠ΅Π»Ρ. Π ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ Π±Π°Π·Ρ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈΡΡ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΡΡΡΠΈΠ΅ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ ΡΡΠΎΠΊΠ° Π² Π΅ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΡΡΠ»ΠΎΠ²ΠΈΡΡ
.In Russian hydropolitics, the Irtysh as the transboundary river is the subject of different level negotiations on the issue of shared use of water resources with the Republic of Kazakhstan and China. In the result of putting in operation of the Upper-Irtysh multireservoir cascade the deterioration of environmental condition, particularly, in a floodplain which has major significance as the source of feed supplies for agricultural production, is observed in the flat part of the Irtysh basin. Therefore, it is important to analyze current condition and changes of different characteristics of hydrological regime of the river, and specifically the minimum flow. The aim of the researchis to indicate the changes of water flow regime and minimum water flow rates in the Irtysh River in the flat part of its basin (in the Republic of Kazakhstan). Research methods. The authors have applies hydrological and geographical approach to analyze standard observational data on the Irtysh flow in the cross section at Semiyarka village - a water level gauge station located directly downstream the multireservoir cascade during two time periods: in natural (1935-1959) and regulated (1967-2010) conditions. Statistical methods were applied: testing homogeneity of the means and variances using the Student t-test and the Fisher F-test, and trend significance using parametric and non-parametric criteria. Results. It is shown that water flow regulation by the Upper-Irtysh multireservoir cascade resulted in significant decrease of minimum summer monthly river discharge (by 22 %), increase of minimum winter river discharge (by 78 %), redistribution of the Irtysh flow between summer (decrease by 38 %) and winter (increase by 70 %) seasons, and, as a consequence, in deterioration of hydrological and environmental condition of the floodplain. Corresponding flow characteristics under natural conditions were used as the base for comparison
ΠΡΠΎΠ΅ΠΊΡ ΠΏΠ»Π°Π½ΠΈΡΠΎΠ²ΠΊΠΈ ΠΈ ΠΌΠ΅ΠΆΠ΅Π²Π°Π½ΠΈΡ ΡΠ΅ΡΡΠΈΡΠΎΡΠΈΠΈ ΠΊΠ²Π°ΡΡΠ°Π»Π° Π² ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²Π΅Π½Π½ΠΎ-Π΄Π΅Π»ΠΎΠ²ΠΎΠΉ Π·ΠΎΠ½Π΅ Π³. Π’ΠΎΠΌΡΠΊΠ°
ΠΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠ° ΠΏΡΠΎΠ΅ΠΊΡΠ° ΠΌΠ΅ΠΆΠ΅Π²Π°Π½ΠΈΡ ΠΎΡΡΡΠ΅ΡΡΠ²Π»ΡΠ΅ΡΡΡ ΠΏΡΠΈΠΌΠ΅Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎ ΠΊ ΡΠ΅ΡΡΠΈΡΠΎΡΠΈΠΈ, ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½Π½ΠΎΠΉ Π² Π³ΡΠ°Π½ΠΈΡΠ°Ρ
ΡΠ»Π΅ΠΌΠ΅Π½ΡΠ° ΠΏΠ»Π°Π½ΠΈΡΠΎΠ²ΠΎΡΠ½ΠΎΠΉ ΡΡΡΡΠΊΡΡΡΡ β Π½Π΅ΠΆΠΈΠ»ΠΎΠ³ΠΎ ΠΊΠ²Π°ΡΡΠ°Π»Π°, ΠΎΠ³ΡΠ°Π½ΠΈΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠΏΠ΅ΠΊΡΠΎΠΌ ΠΠΈΡΠΎΠ²Π°, ΡΠ»ΠΈΡΠ°ΠΌΠΈ ΠΠΈΠ΅Π²ΡΠΊΠ°Ρ, Π£ΡΠΎΠ²Π°, ΠΡΡΡΠΌΠ°. ΠΡΠ°Π½ΠΈΡΡ ΠΊΠ²Π°ΡΡΠ°Π»Π° ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ Π³Π΅Π½Π΅ΡΠ°Π»ΡΠ½ΡΠΌ ΠΏΠ»Π°Π½ΠΎΠΌ Π³ΠΎΡΠΎΠ΄Π° Π’ΠΎΠΌΡΠΊΠ°, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΏΡΠ°Π²ΠΈΠ»Π°ΠΌΠΈ Π·Π΅ΠΌΠ»Π΅ΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΠΈ Π·Π°ΡΡΡΠΎΠΉΠΊΠΈ Π³ΠΎΡΠΎΠ΄Π° Π’ΠΎΠΌΡΠΊΠ°. ΠΡΠΎΠ΅ΠΊΡ ΠΌΠ΅ΠΆΠ΅Π²Π°Π½ΠΈΡ ΠΊΠ²Π°ΡΡΠ°Π»Π° ΠΏΠΎΠ΄Π³ΠΎΡΠ°Π²Π»ΠΈΠ²Π°Π΅ΡΡΡ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΠΏΡΠΎΠ΅ΠΊΡΠ° ΠΏΠ»Π°Π½ΠΈΡΠΎΠ²ΠΊΠΈ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ΅ΡΡΠΈΡΠΎΡΠΈΠΈ Π² ΡΠ΅Π»ΡΡ
ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΈΡ Π³ΡΠ°Π½ΠΈΡ Π·Π΅ΠΌΠ΅Π»ΡΠ½ΡΡ
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