22 research outputs found
Energy Dissipation on Stepped Spillways
The author provided interesting data on stepped spillway flows. The writer would like to add some information on flow resistance of skimming flows and discuss the energy dissipation on stepped chutes. It will be shown that the author's results are not dissimilar with results previously obtained by other researchers
Hydraulics of skimming flows on stepped chutes: The effects of inflow conditions?
Modern stepped spillways are typically designed for large discharge capacities corresponding to a skimming flow regime for which flow resistance is predominantly form drag. The writer demonstrates that the inflow conditions have some effect on the skimming flow properties. Boundary layer calculations show that the flow properties at inception of free-surface aeration are substantially different with pressurized intake. The re-analysis of experimental results highlights that the equivalent Darcy friction factor is f similar to 0.2 in average on uncontrolled stepped Chute and f similar to 0.1 on stepped chute with pressurized intake. A simple design chart is presented to estimate the residual flow velocity, and the agreement of the calculations with experimental results is deemed satisfactory for preliminary design
GPIIb/IIIa Receptor Antagonism Using Small Molecules Provides no Additive Long-Term Protection after Percutaneous Coronary Intervention as Compared to Clopidogrel Plus Aspirin
Background: There is some controversy as to whether tirofiban or eptifibatide, two small anti-aggregating drugs (AAD), may reduce the incidence of composite ischemic events within one year in patients undergoing percutaneous coronary intervention (PCI) in the real clinical world. Methods: We compared consecutive patients on oral double AAD (with clopidogrel and aspirin) who underwent PCI (n=207) and patients who were on single AAD and received a second AAD, just prior to PCI, and either high-dose tirofiban or double-bolus eptifibatide (double AAD plus small molecules group, n=666). The primary end point (incidence of composite ischemic events within one year) included death, acute myocardial infarction, unstable angina, stent thrombosis or repeat PCI or coronary bypass surgery (related to the target vessel PCI failure) and was modelled by Cox's regression. Results: There were 89 composite ischemic events: 24 (11.6%) in double AAD alone and 65 (9.8%) in double AAD plus small molecules groups (log-rank test: p=0.36). Incidences by type of ischemic events were similar between the 2 groups. Based on 21 potential covariates fitted simultaneously, adjusted hazard ratios (HR and 95% confidence intervals) showed that age (HR 1.03, 1.01-1.06, p=0.01), diabetes (HR 1.68, 1.01-2.79, p=0.05) and intra aortic balloon pump (HR 5.12, 2.36-11.10, p=0.0001) were significant risk factors whereas thrombolysis by tenecteplase (HR 0.35, 0.13-0.98, p=0.05) and having had hypertension or anti-hypertensive treatment (HR 0.58, 0.36-0.93, p=0.03) were significant protectors for events. Whether small molecules were present provided a non significant additional benefit as compared to double AAD alone (HR 0.83, 0.51-1.36, p=0.46). Pre-PCI CK-MB were not useful to predict events (HR 1.01, 0.99-1.01, p=0.17). Conclusions: In clinical world patients undergoing PCI (rescue plus primary <13%) while on double AAD, based on clopidogrel plus aspirin, small molecules (tirofiban or eptifibatide) provided no additive long-term protection against the occurrence of composite ischemic events whereas thrombolysis by tenecteplase did. © Schiariti et al
History of Stepped Channels and Spillways: a Rediscovery of the 'Wheel'
Recently, spillways with a stepped profile have regained interest and favor among design engineers to pass flood waters over the dams. The stepped geometry enhances the energy dissipation above the spillway and reduces the size of a downstream stilling basin. In this paper, the author shows that the technique of stepped channels has been developed since Antiquity. Spillways and irrigation channels with stepped profiles were developed by several civilisations around the Mediterranean sea and in America. The main characteristics of the stepped spillways along the ages suggest a regular evolution rather than a revolution. Present stepped spillways are designed to pass similar discharges as two hundred years ago
Ătude expĂ©rimentale de la conductivitĂ© Ă©lectrique du molybdate de COBALT CoMoO
La conductivité électrique du molybdate de cobalt CoMoO4 a été mesurée dans le domaine de température 100-600 °C, à partir d'échantillons pulvérulents sous forme de pastille. Il a été trouvé que la variété a-CoMoO4 est un semi-conducteur de type p, tandis que la variété b-CoMoO4 est un semi-conducteur de type n.Différents mécanismes de conduction ont été trouvés en fonction de la variété polymorphique de CoMoO4 et de la pression partielle d'oxygÚne. Leur nature est discutée
âSegno palpebrale inferiore di Balacco Carlesimo nelle sclerodermieâ
Gli autori rilevano la presenza bilaterale del segno di Balacco-Carlesimo nella sclerodermia. Tale segno consiste nel difficoltoso pinzettamento palpebrale inferiore: segno di Balacco-Carlesimo relativo. Rilevano, inoltre, casi di impossibilitĂ totale al pinzettamento della palpebra inferiore: segno di Balacco-Carlesimo assoluto
âUtilitĂ del test alla quinizarina per la localizzazione della sede di lesione nella sindrome di Claude Bernard-Hornerâ.
Gli autori utilizzano il test con la quinizarina per la localizzazione della sede di lesione nella sindrome di Claude-Bernard-Horner