Preparing students to engage with science‐ and technology‐related misinformation: The role of epistemic insight

Helping students to become more resilient to online misinformation is widely recognised as an essential task for education in a rapidly digitalising world. Students need both scientific knowledge and epistemic insight to navigate online spaces containing sensationalised reports of scientific and technological developments. Epistemic insight involves epistemic curiosity and the ability to think critically about the nature, application and communication of knowledge. This includes developing an understanding of the power and limitations of science and a curiosity regarding its relationship with other disciplines. We present a workshop designed for school students aged 16–18 titled ‘Can science and technology cure loneliness?’, designed to develop students' epistemic insight through investigating loneliness through a multidisciplinary perspective. We discuss how the design and pedagogy of this workshop might help students to build epistemic humility—the recognition that no single disciplinary perspective can complete our knowledge about a given topic. As part of a broader programme, epistemic insight-based pedagogies have the potential to develop students' resistance to science- and technology-related misinformation and prepare them for their potential role in shaping our scientific and technological future

Covid-19 as an opportunity to teach epistemic insight: findings from exploratory workshops on Covid-19 and science with students aged 15–17 in England

The contributions of science and scientists to combatting Covid-19 have been at the forefront of media attention throughout 2020 and early 2021, exposing the public to the processes of science in an unprecedented manner. The pandemic has highlighted the necessity of scientists working collaboratively with other disciplines in informing thinking about a complex, evolving real-world problem. This draws attention to recent efforts, both in the UK and internationally, towards curriculum reform integrating epistemic insight (knowledge about knowledge, including about what disciplines are and how they interact), with significant implications for the teaching of science in schools. We present findings from two exploratory workshops with 15–17-year-old students in England on the role of science during the pandemic. We found that the workshops provided space for students to begin to develop epistemic insight regarding how science informs decision-making in dialogue with other disciplines. We make recommendations proposing pedagogical approaches using live, complex, real-world problems to address issues around understandings of the nature of science, misinformation, trust and participation in science

Apparatus to Measure Optical Scatter of Coatings Versus Annealing Temperature

Light scattered by amorphous thin-film optical coatings limits the sensitivity of interferometric gravitational-wave detectors. We describe an imaging scatterometer to assess the role that crystal growth during annealing plays in this scatter

Quantum Stochastic Processes and the Modelling of Quantum Noise

This brief article gives an overview of quantum mechanics as a {\em quantum probability theory}. It begins with a review of the basic operator-algebraic elements that connect probability theory with quantum probability theory. Then quantum stochastic processes is formulated as a generalization of stochastic processes within the framework of quantum probability theory. Quantum Markov models from quantum optics are used to explicitly illustrate the underlying abstract concepts and their connections to the quantum regression theorem from quantum optics.Comment: 14 pages, invited article for the second edition of Springer's Encyclopedia of Systems and Control (to appear). Comments welcom

Cosmic Explorer: The U.S. Contribution to Gravitational-Wave Astronomy beyond LIGO

This white paper describes the research and development needed over the next decade to realize "Cosmic Explorer," the U.S. node of a future third-generation detector network that will be capable of observing and characterizing compact gravitational-wave sources to cosmological redshifts

Apparatus to Measure Optical Scatter of Coatings Versus Annealing Temperature

Light scattered by amorphous thin-film optical coatings limits the sensitivity of interferometric gravitational-wave detectors. We describe an imaging scatterometer to assess the role that crystal growth during annealing plays in this scatter

Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis

Immunization of volunteers under chloroquine prophylaxis by bites of *Plasmodium falciparum* sporozoite (PfSPZ)–infected mosquitoes induces > 90% protection against controlled human malaria infection (CHMI). We studied intradermal immunization with cryopreserved, infectious PfSPZ in volunteers taking chloroquine (PfSPZ chemoprophylaxis vaccine [CVac]). Vaccine groups 1 and 3 received 3x monthly immunizations with 7.5 x 10^4 PfSPZ. Control groups 2 and 4 received normal saline. Groups 1 and 2 underwent CHMI (#1) by mosquito bite 60 days after the third immunization. Groups 3 and 4 were boosted 168 days after the third immunization and underwent CHMI (#2) 137 days later. Vaccinees (11/20, 55%) and controls (6/10, 60%) had the same percentage of mild to moderate solicited adverse events. After CHMI #1, 8/10 vaccinees (group 1) and 5/5 controls (group 2) became parasitemic by microscopy; the two negatives were positive by quantitative real-time polymerase chain reaction (qPCR). After CHMI #2, all vaccinees in group 3 and controls in group 4 were parasitemic by qPCR. Vaccinees showed weak antibody and no detectable cellular immune responses. Intradermal immunization with up to 3 x 10^5 PfSPZ-CVac was safe, but induced only minimal immune responses and no sterile protection against Pf CHMI. INTRODUCTIO

A Cryogenic Silicon Interferometer for Gravitational-wave Detection

The detection of gravitational waves from compact binary mergers by LIGO has opened the era of gravitational wave astronomy, revealing a previously hidden side of the cosmos. To maximize the reach of the existing LIGO observatory facilities, we have designed a new instrument able to detect gravitational waves at distances 5 times further away than possible with Advanced LIGO, or at greater than 100 times the event rate. Observations with this new instrument will make possible dramatic steps toward understanding the physics of the nearby Universe, as well as observing the Universe out to cosmological distances by the detection of binary black hole coalescences. This article presents the instrument design and a quantitative analysis of the anticipated noise floor

A Cryogenic Silicon Interferometer for Gravitational-wave Detection

The detection of gravitational waves from compact binary mergers by LIGO has opened the era of gravitational wave astronomy, revealing a previously hidden side of the cosmos. To maximize the reach of the existing LIGO observatory facilities, we have designed a new instrument that will have 5 times the range of Advanced LIGO, or greater than 100 times the event rate. Observations with this new instrument will make possible dramatic steps toward understanding the physics of the nearby universe, as well as observing the universe out to cosmological distances by the detection of binary black hole coalescences. This article presents the instrument design and a quantitative analysis of the anticipated noise floor