Ocular hypertension in myopia: analysis of contrast sensitivity

Purpose: we evaluated the evolution of contrast sensitivity reduction in patients affected by ocular hypertension and glaucoma, with low to moderate myopia. We also evaluated the relationship between contrast sensitivity and mean deviation of visual field. Material and methods: 158 patients (316 eyes), aged between 38 and 57 years old, were enrolled and divided into 4 groups: emmetropes, myopes, myopes with ocular hypertension (IOP≥21 ±2 mmHg), myopes with glaucoma. All patients underwent anamnestic and complete eye evaluation, tonometric curves with Goldmann’s applanation tonometer, cup/disc ratio evaluation, gonioscopy by Goldmann’s three-mirrors lens, automated perimetry (Humphrey 30-2 full-threshold test) and contrast sensitivity evaluation by Pelli-Robson charts. A contrast sensitivity under 1,8 Logarithm of the Minimum Angle of Resolution (LogMAR) was considered abnormal. Results: contrast sensitivity was reduced in the group of myopes with ocular hypertension (1,788 LogMAR) and in the group of myopes with glaucoma (1,743 LogMAR), while it was preserved in the group of myopes (2,069 LogMAR) and in the group of emmetropes (1,990 LogMAR). We also found a strong correlation between contrast sensitivity reduction and mean deviation of visual fields in myopes with glaucoma (coefficient relation = 0.86) and in myopes with ocular hypertension (coefficient relation = 0.78). Conclusions: the contrast sensitivity assessment performed by the Pelli-Robson test should be performed in all patients with middle-grade myopia, ocular hypertension and optic disc suspected for glaucoma, as it may be useful in the early diagnosis of the disease. Introduction Contrast can be defined as the ability of the eye to discriminate differences in luminance between the stimulus and the background. The sensitivity to contrast is represented by the inverse of the minimal contrast necessary to make an object visible; the lower the contrast the greater the sensitivity, and the other way around. Contrast sensitivity is a fundamental aspect of vision together with visual acuity: the latter defines the smallest spatial detail that the subject manages to discriminate under optimal conditions, but it only provides information about the size of the stimulus that the eye is capable to perceive; instead, the evaluation of contrast sensitivity provides information not obtainable with only the measurement of visual acuity, as it establishes the minimum difference in luminance that must be present between the stimulus and its background so that the retina is adequately stimulated to perceive the stimulus itself. The clinical methods of examining contrast sensitivity (lattices, luminance gradients, variable-contrast optotypic tables and lowcontrast optotypic tables) relate the two parameters on which the ability to distinctly perceive an object depends, namely the different luminance degree of the two adjacent areas and the spatial frequency, which is linked to the size of the object. The measurement of contrast sensitivity becomes valuable in the diagnosis and follow up of some important eye conditions such as glaucoma. Studies show that contrast sensitivity can be related to data obtained with the visual perimetry, especially with the perimetric damage of the central area and of the optic nerve head

SBV Regularity for Genuinely Nonlinear, Strictly Hyperbolic Systems of Conservation Laws in one space dimension

We prove that if $t \mapsto u(t) \in \mathrm {BV}(\R)$ is the entropy solution to a $N \times N$ strictly hyperbolic system of conservation laws with genuinely nonlinear characteristic fields $$u_t + f(u)_x = 0,$$ then up to a countable set of times $\{t_n\}_{n \in \mathbb N}$ the function $u(t)$ is in $\mathrm {SBV}$, i.e. its distributional derivative $u_x$ is a measure with no Cantorian part. The proof is based on the decomposition of $u_x(t)$ into waves belonging to the characteristic families $$u(t) = \sum_{i=1}^N v_i(t) \tilde r_i(t), \quad v_i(t) \in \mathcal M(\R), \ \tilde r_i(t) \in \mathrm R^N,$$ and the balance of the continuous/jump part of the measures $v_i$ in regions bounded by characteristics. To this aim, a new interaction measure \mu_{i,\jump} is introduced, controlling the creation of atoms in the measure $v_i(t)$. The main argument of the proof is that for all $t$ where the Cantorian part of $v_i$ is not 0, either the Glimm functional has a downward jump, or there is a cancellation of waves or the measure $\mu_{i,\mathrm{jump}}$ is positive

On the stability of the standard Riemann semigroup

We consider the dependence of the entropic solution of a hyperbolic system of conservation laws {ut + f(u)x = 0, u(0, \ub7) = u0 on the flux function f. We prove that the solution is Lipschitz continuous w.r.t, the C0 norm of the derivative of the perturbation of f. We apply this result to prove the convergence of the solution of the relativistic Euler equation to the classical limit

SBV regularity of Systems of Conservation Laws and Hamilton-Jacobi Equation

We review the SBV regularity for solutions to hyperbolic systems of conservation laws and Hamilton-Jacobi equations. We give an overview of the techniques involved in the proof, and a collection of related problems concludes the paper

Biologia reprodutiva e polinização de Jacquemontia nodiflora (Desr.) G. Don (Convolvulaceae) em Caatinga na região de Petrolina, PE, Brasil.

O principal objetivo deste trabalho foi estudar aspectos da biologia da polinização, comportamento e frequência de visitantes florais, reprodução e fenologia de Jacquemontia nodiflora em área de Caatinga hiperxerófila, em Petrolina-PE, no período de março de 2004 a março de 2005. Os dados fenológicos mostraram que a brotação, floração e frutificação concentram-se na estação chuvosa, enquanto a senescência foliar ocorre na estação seca, indicando a influência de precipitação no processo de reprodução. As flores estão reunidas em cimeiras, são pequenas (10 mm de diâmetro), curto-campanuladas, brancas, inodoras e secretam pequena quantidade de néctar ( 90%) e por polinização cruzada (75,6%). Jacquemontia nodiflora pode ser considerada como uma importante fonte de néctar para abelhas de tamanho médio e pequeno, sendo A. mellifera, T. spinipes e F. doederleini consideradas como polinizadores desta espécie

Modelling defects in Ni-Al with EAM and DFT calculations

We present detailed comparisons between the results of embedded atom model (EAM) and density functional theory (DFT) calculations on defected Ni alloy systems. We find that the EAM interatomic potentials reproduce low-temperature structural properties in both the γ and ${{\gamma}^{\prime}}$ phases, and yield accurate atomic forces in bulk-like configurations even at temperatures as high as  ~1200 K. However, they fail to describe more complex chemical bonding, in configurations including defects such as vacancies or dislocations, for which we observe significant deviations between the EAM and DFT forces, suggesting that derived properties such as (free) energy barriers to vacancy migration and dislocation glide may also be inaccurate. Testing against full DFT calculations further reveals that these deviations have a local character, and are typically severe only up to the first or second neighbours of the defect. This suggests that a QM/MM approach can be used to accurately reproduce QM observables, fully exploiting the EAM potential efficiency in the MM zone. This approach could be easily extended to ternary systems for which developing a reliable and fully transferable EAM parameterisation would be extremely challenging e.g. Ni alloy model systems with a W or Re-containing QM zone

SPECTROSCOPIC STUDY OF Q CYGNI: SURPRISES FROM AN OLD NOVA

We present a time-resolved spectroscopic study of Q Cyg (Nova Cyg 1876), determining a period of P = 10.08 hr for the system. Our data also reveal P Cygni profiles in the He I λλ5876 and 7065 lines and occasionally in the Hα line. Although P Cygni profiles commonly appear in the UV resonance lines of novalike cataclysmic variables, only BZ Cam was previously known to exhibit a rapidly variable wind, which leaves its signature in time-resolved optical spectral lines. A comparison between BZ Cam and Q Cyg reveals striking similarities between the two systems. The origin of the outflow in Q Cyg and a possible correlation of the P Cygni profiles with the system's optical state are discussed