Invertible Mosaic Image Hiding Network for Very Large Capacity Image Steganography

The existing image steganography methods either sequentially conceal secret images or conceal a concatenation of multiple images. In such ways, the interference of information among multiple images will become increasingly severe when the number of secret images becomes larger, thus restrict the development of very large capacity image steganography. In this paper, we propose an Invertible Mosaic Image Hiding Network (InvMIHNet) which realizes very large capacity image steganography with high quality by concealing a single mosaic secret image. InvMIHNet consists of an Invertible Image Rescaling (IIR) module and an Invertible Image Hiding (IIH) module. The IIR module works for downscaling the single mosaic secret image form by spatially splicing the multiple secret images, and the IIH module then conceal this mosaic image under the cover image. The proposed InvMIHNet successfully conceal and reveal up to 16 secret images with a small number of parameters and memory consumption. Extensive experiments on ImageNet-1K, COCO and DIV2K show InvMIHNet outperforms state-of-the-art methods in terms of both the imperceptibility of stego image and recover accuracy of secret image

Reexamine the dark matter scenario accounting for the positron excess in a new cosmic ray propagation model

The positron excess in cosmic rays has stimulated a lot of interests in the last decade. The dark matter origin of the extra positrons has attracted great attention. However, the $\gamma$-ray search set very stringent constraints on the dark matter annihilation/decay rate, which leads to great disfavor of the dark matter scenario. In the work, we incorporate the recent progress in cosmic rays propagation and reexamine the dark matter scenario accounting for the positron excess. Recent observations indicate that cosmic rays propagation in the Milky Way may be not uniform and diffusion in the Galactic disk should be slower than that in the halo. In the spatial-dependent propagation model, the positrons/electrons are more concentrated in the disk and lead to smaller dark matter annihilation/decay rate to account for the positron excess and also a smaller deficit in the background positron flux. Especially for the $\mu^+\mu^-$ channel the positron spectrum fit the AMS-02 latest data perfectly and the annihilation rate satisfies all the present constraints from $\gamma$-ray and CMB observations.Comment: 11 pages, 4 figure

A General Pattern-Based Design Optimization for Asymmetric Spoke-Type Interior PM Machines

A novel asymmetric spoke-type interior permanent magnet (AS-IPM) machine is proposed in this paper. It utilizes the magnetic-field-shifting (MFS) effect to improve the torque performance, which achieves a high utilization ratio of both permanent magnet (PM) torque and reluctance torque. In addition, a general pattern of rotor topologies is proposed to represent all possible machine structures. Various rotor structures can be obtained by changing the design parameters of the general pattern. A non-dominated sorting genetic algorithm II (NSGA-II) is adopted to automatically search for optimal rotor configurations. With the aid of the optimization program, an asymmetric spoke-type rotor structure with improved performance is obtained. To showcase the advantages of the proposed machine, the electromagnetic performance is compared between a conventional spoke-type interior permanent magnet (S-IPM) machine and a proposed AS-IPM machine. The finite-element simulation results show that the optimal design of the AS-IPM performs a 7.7% higher output torque ripple due to the MFS effect while the total PM volume remains the same. Meanwhile, the torque ripple of the proposed structure is significantly reduced by 82.1%

Establishment and assessments of a new model for the postoperative fatigue syndrome by major small intestinal resection in rats

Objective. Postoperative fatigue syndrome (POFS) is a general and main complication after surgery. However, there is no stable and standardized animal model for POFS. The aim of the present study was to establish a rodent model of POFS by small intestinal resection, with POFS evaluated by acknowledged physical and behavioral methods. Material and Methods. Forty-two Sprague-Dawley rats were randomly divided into four groups according to the length of a "middle" small intestinal resection: 0% (sham group; i.e., laparotomy alone), 10%, 40% and 70% groups, with corresponding lengths of small intestinal resections. Following surgery, the general state of health was evaluated. Tail suspension test, open field test and Morris water maze test were used to evaluate the degree of POFS. Serum albumin, transferrin, prealbumin and fibronectin were measured to assess the nutritional status, and superoxide dismutase (SOD) and malondialdehyde (MDA) were also measured. Results. As compared with the other three groups, the 70% small intestinal resection group showed the worst general state of health, decreased strength of the tail suspension test and decreased score of Morris water maze test (p < 0.05) after operation. All rats in whom the small intestinal resection was done demonstrated a certain degree of malnutrition and behavior of depression, and the 70% resection group had the lowest levels of transferrin, prealbumin and fibronectin as compared with the other groups (p < 0.05), as well as decreased SOD and increased MDA in serum (p < 0.05). Conclusions. Resection of 70% of the small intestine resulted in typical characteristics of POFS. As this procedure is simple, stable and easily reproducible, it may serve as a model for research on POFS

Identification and functional analysis of a novel PRKAG2 mutation responsible for Chinese PRKAG2 cardiac syndrome reveal an important role of non-CBS domains in regulating the AMPK pathway

AbstractBackgroundPRKAG2 gene encodes the γ2 regulatory subunit of AMP-activated protein kinase (AMPK) that acts as a sensor of cellular energy status, and its germline mutations are responsible for PRKAG2 cardiac syndrome (PCS). The majority of missense mutations of cystathionine beta-synthase (CBS) domains found in PCS impair the binding activity of PRKAG2 to adenosine derivatives, and therefore lead to PRKAG2 function impairment and AMPK activity alteration, resulting in a familial syndrome of ventricular preexcitation, conduction defects, and cardiac hypertrophy. However, it is unclear about the PRKAG2 mutation in the non-CBS domain. Here, a Chinese family exhibiting the cardiac syndrome associated with a novel heterozygous PRKAG2 mutation (Gly100Ser) mapped to exon 3 encoding a non-CBS domain is described and the function of this novel mutation was investigated in vitro.MethodsThe PRKAG2 G100S and R302Q mutations were constructed by a two-step polymerase chain reaction and then transfected into CCL13 cells by lentivirus vectors. Wild-type PRKAG2 gene transfection was used as a negative control. PRKAG2 expression was determined by Western blot. Immunofluorescence was used to localize the intracellular PRKAG2 proteins. MTT assay was performed to explore the effect of mutations on cell proliferation. Periodic acid-Schiff staining was used for detecting glycogen accumulation. AMPK concentration was measured with enzyme-linked immunosorbent assay.ResultsOur results showed neither intracellular localization of PRKAG2 nor cell growth was altered. In contrast, PRKAG2 protein expression levels were significantly reduced by this mutation. Furthermore, PRKAG2-mediated activity of AMPK was attenuated, resulting in glycogen metabolism dysregulation. These findings revealed that non-CBS domains of PRKAG2 were essential to the regulation of AMPK activity, similar to CBS.ConclusionsOur study ascribes a crucial regulatory role to the novel PRKAG2 G100S mutation, and reiterates that PCS occurs as a consequence of AMPK signaling abnormality caused by PRKAG2 gene mutations

Innovative inbuilt moving bed biofilm reactor for nitrogen removal applied in household aquarium

An innovative inbuilt moving bed biofilm reactor (MBBR) was created to protect fish from nitrogen in a household aquarium. During the 90 experimental days, the ammonia nitrogen (NH4+-N) concentration in the aquarium with the inbuilt MBBR was always below 0.5 mg/L, which would not threaten the fish. Concurrently, nitrite and nitrate nitrogen concentrations were always below 0.05 mg/L and 4.5 mg/L, respectively. However, the blank contrast aquarium accumulated 1.985 mg/L NH4+-N on the 16th day, which caused the fish to die. The suspended biofilms could achieve the specific NH4+-N removal rate of 45.43 g/m3/d. Biofilms presented sparsely with filamentous structures and showed certain degrees of roughness. The bacterial communities of the suspended biofilms and the sediment were statistically different (p &lt; 0.05), reflected in denitrifying and nitrifying bacteria. In particular, the relative abundance of Nitrospira reached 1.4%, while the genus was barely found in sediments. The suspended biofilms showed potentials for nitrification function with the predicted sequence numbers of ammonia monooxygenase [1.14.99.39] and hydroxylamine dehydrogenase [EC:1.7.2.6] of 220 and 221, while the values of the sediment were only 5 and 1. This study created an efficient NH4+-N removal inbuilt MBBR for household aquariums and explored its mechanism to afford a basis for its utilization

Deep sequencing identifies novel and conserved microRNAs in peanuts (Arachis hypogaea L.)

<p>Abstract</p> <p>Background</p> <p>MicroRNAs (miRNAs) are a new class of small, endogenous RNAs that play a regulatory role in the cell by negatively affecting gene expression at the post-transcriptional level. miRNAs have been shown to control numerous genes involved in various biological and metabolic processes. There have been extensive studies on discovering miRNAs and analyzing their functions in model species, such as <it>Arabidopsis </it>and rice. Increasing investigations have been performed on important agricultural crops including soybean, conifers, and <it>Phaselous vulgaris </it>but no studies have been reported on discovering peanut miRNAs using a cloning strategy.</p> <p>Results</p> <p>In this study, we employed the next generation high through-put Solexa sequencing technology to clone and identify both conserved and species-specific miRNAs in peanuts. Next generation high through-put Solexa sequencing showed that peanuts have a complex small RNA population and the length of small RNAs varied, 24-nt being the predominant length for a majority of the small RNAs. Combining the deep sequencing and bioinformatics, we discovered 14 novel miRNA families as well as 75 conserved miRNAs in peanuts. All 14 novel peanut miRNAs are considered to be species-specific because no homologs have been found in other plant species except ahy-miRn1, which has a homolog in soybean. qRT-PCR analysis demonstrated that both conserved and peanut-specific miRNAs are expressed in peanuts.</p> <p>Conclusions</p> <p>This study led to the discovery of 14 novel and 22 conserved miRNA families from peanut. These results show that regulatory miRNAs exist in agronomically important peanuts and may play an important role in peanut growth, development, and response to environmental stress.</p