Relationships between components of blood pressure and cardiovascular events in patients with stable coronary artery disease and hypertension

Observational studies have shown a J-shaped relationship between diastolic blood pressure (BP) and cardiovascular events in hypertensive patients with coronary artery disease. We investigated whether the increased risk associated with low diastolic BP reflects elevated pulse pressure (PP). In 22 672 hypertensive patients with coronary artery disease from the CLARIFY registry (Prospective Observational Longitudinal Registry of Patients With Stable Coronary Artery Disease), followed for a median of 5.0 years, BP was measured annually and averaged. The relationships between PP and diastolic BP, alone or combined, and the primary composite outcome (cardiovascular death or myocardial infarction) were analyzed using multivariable Cox proportional hazards models. Adjusted hazard ratios for the primary outcome were 1.62 (95% confidence interval [CI], 1.40–1.87), 1.00 (ref), 1.07 (95% CI, 0.94–1.21), 1.54 (95% CI, 1.32–1.79), and 2.34 (95% CI, 1.95–2.81) for PP<45, 45 to 54 (reference), 55 to 64, 65 to 74, and ≥75 mm Hg, respectively, and 1.50 (95% CI, 1.31–1.72), 1.00 (reference), and 1.58 (95% CI, 1.42–1.77) for diastolic BPs of <70, 70 to 79 (ref), and ≥80 mm Hg, respectively. In a cross-classification analysis between diastolic BP and PP, the relationship between diastolic BP and the primary outcome remained J-shaped when the analysis was restricted to patients with the lowest-risk PP (45–64 mm Hg), with adjusted hazard ratios of 1.53 (95% CI, 1.27–1.83), 1.00 (ref), and 1.54 (95% CI, 1.34–1.75) in the <70, 70 to 79 (reference), and ≥80 mm Hg subgroups, respectively. The J-shaped relationship between diastolic BP and cardiovascular events in hypertensive patients with coronary artery disease persists in patients within the lowest-risk PP range and is therefore unlikely to be solely the consequence of an increased PP reflecting advanced vascular disease

Combinatorial Effect of Fertigation Rate and Scheduling on Tomato Performance under Naturally Ventilated Polyhouse in Indian Humid Sub-Tropics

Protected cultivation is a resource-efficient method of crop production, however, at the same time, it is resource intensive. An optimum rate and time of fertilizer application is required in order to maximize crop yield vis-a-vis resource use efficiency. However, these aspects are scarcely studied for tomato under low- and medium-tech greenhouses in Indian humid sub-tropics. In this regard, a two-year study was conducted to assess the effect of four NPK fertilization rates (i.e., 120, 100, 80, and 60% of the recommended dose of fertilizers, RDF) and three fertigation scheduling approaches-fertigation at different stages in different proportions of NPK, along with an additional treatment, i.e., farmers' practice (soil-based application of recommended NPK) for tomatoes under a naturally ventilated polyhouse. The plant growth attributes, the tomato yield- and quality-related traits, the nutrient (NPK) accumulation by the plants, the water use efficiency (WUE), and economics were studied in response to different fertigation rates and scheduling approaches. These parameters were affected by both the rates of NPK fertilization and their time of application (scheduling) over the different growth stages. Among the different rates and time of fertigation, the recommended dose of fertilizer (100% RDF) (i.e., 300 kg N, 150 kg P2O5, and 150 kg K2O per ha and their scheduling as 15% N, 10% P2O5, and 10% K2O of RDF during 15-45 days after transplanting (P-1); 40% N, 40% P2O5, and 40% K2O of RDF during 47-76 DAT (P-2); 30% N, 40% P2O5, and 40% K2O of RDF during 77-107 DAT (P-3); and 15% N, 10% P2O5, and 10% K2O of RDF during 108-138 DAT (P-4)) was found to be the optimum for fruit yield, WUE, and economics of tomato under protected condition

Serials Spoken Here–Reports of Conferences, Institutes and Seminars

This quarter's column offers a report from the Acquisitions Institute at Timberline Lodge, held May 14–17, 2016, in Timberline Lodge, Oregon, and also provides coverage of multiple sessions from the Kraemer Copyright Conference, held June 6–7, 2016, in Colorado Springs, Colorado. Some reports are collected, as well, from the NASIG Annual Conference, held June 9–12, 2016, in Albuquerque, New Mexico, and the American Library Association (ALA) Annual Conference, held June 23–28, 2016, in Orlando, Florida. Lastly, there is a report from the International Federation of Library Associations and Institutions (IFLA) World Library and Information Congress, held August 13–19, 2016, in Columbus, Ohio. Topics covered include open access, linked data, copyright, text mining, e-resource management, and digitization

Neutron-Proton Scattering in the Context of the d∗d^*(2380) Resonance

New data on quasifree polarized neutron-proton scattering, in the region of the recently observed $d^*$ resonance structure, have been obtained by exclusive and kinematically complete high-statistics measurements with WASA at COSY. This paper details the determination of the beam polarization, checks of the quasifree character of the scattering process, on all obtained $A_y$ angular distributions and on the new partial-wave analysis, which includes the new data producing a resonance pole in the $^3D_3$-$^3G_3$ coupled partial waves at ($2380\pm10 - i40\pm5$) MeV -- in accordance with the $d^*$ dibaryon resonance hypothesis. The effect of the new partial-wave solution on the description of total and differential cross section data as well as specific combinations of spin-correlation and spin-transfer observables available from COSY-ANKE measurements at $T_d$ = 2.27 GeV is discussed

Evidence for a New Resonance from Polarized Neutron-Proton Scattering

Exclusive and kinematically complete high-statistics measurements of quasifree polarized $\vec{n}p$ scattering have been performed in the energy region of the narrow resonance structure $d^*$ with $I(J^P) = 0(3^+)$, $M \approx$ 2380 MeV/$c^2$ and $\Gamma \approx$ 70 MeV observed recently in the double-pionic fusion channels $pn \to d\pi^0\pi^0$ and $pn \to d\pi^+\pi^-$. The experiment was carried out with the WASA detector setup at COSY having a polarized deuteron beam impinged on the hydrogen pellet target and utilizing the quasifree process $\vec{d}p \to np + p_{spectator}$. That way the $np$ analyzing power $A_y$ was measured over a large angular range. The obtained $A_y$ angular distributions deviate systematically from the current SAID SP07 NN partial-wave solution. Incorporating the new $A_y$ data into the SAID analysis produces a pole in the $^3D_3 - ^3G_3$ waves as expected from the $d^*$ resonance hypothesis

ABC Effect and Resonance Structure in the Double-Pionic Fusion to 3^3He

Exclusive and kinematically complete measurements of the double pionic fusion to $^3$He have been performed in the energy region of the so-called ABC effect, which denotes a pronounced low-mass enhancement in the $\pi\pi$-invariant mass spectrum. The experiments were carried out with the WASA detector setup at COSY. Similar to the observations in the basic $pn \to d \pi^0\pi^0$ reaction and in the $dd \to ^4$He$\pi^0\pi^0$ reaction, the data reveal a correlation between the ABC effect and a resonance-like energy dependence in the total cross section. Differential cross sections are well described by the hypothesis of $d^*$ resonance formation during the reaction process in addition to the conventional $t$-channel $\Delta\Delta$ mechanism. The deduced $d^*$ resonance width can be understood from collision broadening due to Fermi motion of the nucleons in initial and final nuclei

Measurement of the η→π+π−π0\eta\to\pi^+\pi^-\pi^0 Dalitz plot distribution

Dalitz plot distribution of the $\eta\to\pi^+\pi^-\pi^0$ decay is determined using a data sample of $1.2\cdot 10^7$ $\eta$ mesons from $pd\to ^3\textrm{He}\eta$ reaction at 1 GeV collected by the WASA detector at COSY.Comment: 13 pages, 6 figure