5 research outputs found
Inverse Design of Aluminium Alloys Using Genetic Algorithm: A Class-Based Workflow
The design of aluminium alloys often encounters a trade-off between strength and ductility, making it challenging to achieve desired properties. Adding to this challenge is the broad range of alloying elements, their varying concentrations, and the different processing conditions (features) available for alloy production. Traditionally, the inverse design of alloys using machine learning involves combining a trained regression model for the prediction of properties with a multi-objective genetic algorithm to search for optimal features. This paper presents an enhancement in this approach by integrating data-driven classes to train class-specific regressors. These models are then used individually with genetic algorithms to search for alloys with high strength and elongation. The results demonstrate that this improved workflow can surpass traditional class-agnostic optimisation in predicting alloys with higher tensile strength and elongation
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Influence of Preoperative T1-Slope and Cervical Sagittal Vertical Axis on Postoperative Cervical Sagittal Alignment Following Posterior Cervical Laminoplasty.
BackgroundAssess correlation between preoperative cervical sagittal alignment (T1 slope [T1S] and C2-C7 cervical sagittal vertical axis [cSVA]) and postoperative cervical sagittal balance after posterior cervical laminoplasty.MethodsConsecutive patients who underwent laminoplasty at a single institution with >6 weeks postoperative follow-up were divided into 4 groups based on preoperative cSVA and T1S (Group 1: cSVA <4 cm/T1S <20°; Group 2: cSVA ≥4 cm/T1S ≥20°; Group 3: cSVA <4 cm/T1S ≥20°; Group 4: cSVA <4 cm/T1S <20°). Radiographic analyses were conducted at 3 timepoints, and changes in cSVA, C2-C7 cervical lordosis (CL), and T1S -CL were compared.ResultsA total of 214 patients met inclusion criteria (28 patients had cSVA <4 cm/T1S <20° [Group 1]; 47 patients had cSVA ≥4 cm/T1S ≥20° [Group 2]; 139 patients had cSVA <4 cm/T1S ≥20° [Group 3]). No patients had cSVA ≥4 cm/T1S <20° (Group 4). Patients either had a C4-C6 (60.7%) or C3-C6 (39.3%) laminoplasty. Mean follow-up was 1.6 ± 1.32 years. For all patients, mean cSVA increased 6 mm postoperatively. cSVA significantly increased postoperatively for both groups with a preoperative cSVA <4 cm (ie, Groups 1 and 3 [P < 0.01]). For all patients, mean CL decreased 2° postoperatively. Groups 1 and 2 had significant differences in preoperative CL but nonsignificant differences at 6 weeks (P = 0.41) and last follow-up (P = 0.06).ConclusionCervical laminoplasty resulted in a mean decrease in CL. Patients with high preoperative T1S, irrespective of cSVA, were at risk of loss of CL postoperatively. While patients with low preoperative T1S and cSVA <4 cm experienced a decrease in global sagittal cervical alignment, CL was not jeopardized.Clinical relevanceThe results of this study may facilitate preoperative planning for patients undergoing posterior cervical laminoplasty.Level of evidence: