Diagnostic Value Parameters Of Acute Phase Reactances Of Infectious-inflammatory Process In Diagnostics Of Early Neonatal Sepsis

An advanced progress of clinical neonatology in recent years has enabled to achieve considerable success in newborn management with due respect to both medical treatment and general care, especially in the group of neonates with low body weight at birth. At the same time, neonatal sepsis in the early period still predetermine sickness and mortality of newborns.Material and methods. Clinical-paraclinical indices with detection of diagnostic value of C-reactive protein and interleukins-6 and 8 were evaluated in 100 neonates with available susceptibility factors to early neonatal infection from mother\u27s side and clinical signs of organ dysfunction in neonates with precautions of generalized infectious-inflammatory process at the end of their first day of life.Results. The data obtained substantiate that low concentrations of IL-6 and IL-8 prevail, and therefore the mentioned mediators hardly can be used to verify early neonatal infection. In the majority of children C-reactive protein elevated the concentration of 10.0 mg/L which is traditionally considered to be a discriminant as to the verification of an infectious process in newborns.Conclusions. None of the clinical signs associated with infectious-inflammatory process in newborns in the first two days of their life enabled to verify reliably availability of systemic bacterial infection

High-multiplicity muon events observed with EMMA array

Abstract High-multiplicity data, collected with a segmented scintillator array of the cosmic-ray experiment EMMA (Experiment with Multi-Muon Array), is presented for the first time. The measurements were done at the depth of 75 meters (210 m.w.e.) in the Pyhäsalmi mine in Finland. EMMA uses two types of detectors: drift chambers and plastic scintillation detectors. The presented data were acquired over the period between December, 2015 and April, 2018 using 128-800 plastic scintillator pixels probing the fiducial area of ˜100 m². The results are being interpreted in terms of CORSIKA simulations. Several events with densities in excess of 10 muons per m² were observed. At the next stage of the analysis, the high-multiplicity events will be matched with precision tracking data extracted from the multi-layer drift chambers of EMMA. Observation of high-density muon bundles was first reported by the LEP experiments: DELPHI, L3+C, and ALEPH. More recently, the ALICE experiment at CERN has provided new cosmic-ray results together with improved interpretation benefiting from the updated cross section values extracted from LHC results. While the tracking performance of ALICE is superior to EMMA, the duration of ALICE cosmic-ray measurements is very limited. Over the period of 2010–2018 the total exposure was only 93 days while EMMA, having a similar overburden provides a larger footprint and collects data continuously

Cosmic-ray muon flux at Canfranc Underground Laboratory

Abstract Residual flux and angular distribution of high-energy cosmic muons have been measured in two underground locations at the Canfranc Underground Laboratory (LSC) using a dedicated Muon Monitor. The instrument consists of three layers of fast scintillation detector modules operating as 352 independent pixels. The monitor has a flux-defining area of 1 m² and covers all azimuth angles, and zenith angles up to 80°. The measured integrated muon flux is (5.26±0.21)×10⁻³ m⁻²s⁻¹ in the Hall A of the LAB2400 and (4.29±0.17)×10⁻³3 m⁻²s⁻¹ in LAB2500. The angular dependence is consistent with the known profile and rock density of the surrounding mountains. In particular, there is a clear maximum in the flux coming from the direction of the Rioseta valley

NESTOR: A status report

NESTOR is an underwater neutrino astrophysics laboratory to be located in the international waters of the southwest of Greece. The first phase of this experiment is the construction and deployment of one hexagonal tower consisting of 168 optical modules, with effective are of 20000m2 for E ⩾ TeV neutrinos. Over the past few years detailed studies of the site have been carried out while many tests have been performed. The current status of the preparation of the experiment and the future plans will be presented