Architecture Blueprint in Strategic Alignment

Increasingly, IT architecture is seen as the obvious instrument for decision making in the strategicalignment between the business domain and the technology domain. However field experiences showwe are far from the point that the business domain broadly uses architecture, while strategic alignmentis high on the agenda of many CIO’s. It looks like there is a fundamental disconnect in thecommunication process between the worlds of business and IT. This paper discusses which formaspects an architecture blueprint must have in the communication process with strategic alignment toovercome this disconnection. For this purpose, a couple principles are proposed for architectureblueprints to contribute to a successful alignment between the business domain and the technologydomain

Quantifying excitations of quasinormal mode systems

Computations of the strong field generation of gravitational waves by black hole processes produce waveforms that are dominated by quasinormal (QN) ringing, a damped oscillation characteristic of the black hole. We describe here the mathematical problem of quantifying the QN content of the waveforms generated. This is done in several steps: (i) We develop the mathematics of QN systems that are complete (in a sense to be defined) and show that there is a quantity, the ``excitation coefficient,'' that appears to have the properties needed to quantify QN content. (ii) We show that incomplete systems can (at least sometimes) be converted to physically equivalent complete systems. Most notably, we give a rigorous proof of completeness for a specific modified model problem. (iii) We evaluate the excitation coefficient for the model problem, and demonstrate that the excitation coefficient is of limited utility. We finish by discussing the general question of quantification of QN excitations, and offer a few speculations about unavoidable differences between normal mode and QN systems.Comment: 27 pages, 14 figures. To be published in: J. Math. Phys. (1999

Explaining Giant Apparent pKA\mathrm{p}K_\mathrm{A} Shifts in Weak Polyelectrolyte Brushes

Recent experiments on weak polyelectrolyte brushes found marked shifts in the effective p$K_\mathrm{A}$ that are linear in the logarithm of the salt concentration. Comparing explicit-particle simulations with mean-field calculations we show that for high grafting densities the salt concentration effect can be explained using the ideal Donnan theory, but for low grafting densities the full shift is due to a combination of the Donnan effect and the polyelectrolyte effect. The latter originates from electrostatic correlations which are neglected in the Donnan picture and which are only approximately included in the mean-field theory. Moreover, we demonstrate that the magnitude of the polyelectrolyte effect is almost invariant with respect to salt concentration but depends on the grafting density of the brush. This invariance is due to a complex cancellation of multiple effects. Based on our results, we show how the experimentally determined p$K_\mathrm{A}$ shifts may be used to infer the grafting density of brushes, a parameter that is difficult to measure directly.Comment: First revised version of the manuscript; 15 pages, 16 figure

Virtual Library Matthäus Daniel Pöppelmann

The „Virtual Library Matthäus Daniel Pöppelmann“ is planned as a book index with attached weblinks to digitized historical printed works and reflects the former, in original lost private library of the famous baroque architect in Dresden. The index was developed in 2013/14 by the subproject-team of the TU Dresden within the European Network of Baroque Cultural Heritage (ENBaCH). In 2017 the virtual library has been brought up-to-date with regard to the transcribed book titles and the additional weblinks within the context of the Project Matthäus Daniel Pöppelmann (1662-1736): Die Schloss- und Zwingerplanungen für Dresden. Planen und Bauen im “modus romanus” of the TU Dresden, supported by the Fritz-Thyssen-Stiftung

Sprachstandardisierung unter Mehrsprachigkeitsbedingungen. Das Deutsche in Luxemburg im 19. Jahrhundert

Der Beitrag beschreibt die Grundstruktur des Forschungsprojekts ‚Standardization in Diversity (SDiv). The case of German in Luxembourg 1795–1920‘, das im Zeitraum 2013–2016 vom Fonds National de la Recherche (Luxemburg) und der DFG gefördert wird. Weitere Informationen auf der Internetseite des Projekts unter http://infolux.uni.lu/standardization

Failure of Sterne- and Pasteur-Like Strains of Bacillus anthracis to Replicate and Survive in the Urban Bluebottle Blow Fly Calliphora vicina under Laboratory Conditions

Britta von Terzi, Peter C. B. Turnbull, Wolfgang Beyer, University of Hohenheim, Institute of Environmental and Animal Hygiene, Stuttgart, GermanySteve E. Bellan, Center for Computational Biology and Bioinformatics, University of Texas at Austin, Austin, Texas, United States of AmericaThis study aimed to elucidate the bacteriological events occurring within the gut of Calliphora vicina, selected as the European representative of blow flies held responsible for the spread of anthrax during epidemics in certain parts of the world. Green-fluorescent-protein-carrying derivatives of Bacillus anthracis were used. These lacked either one of the virulence plasmids pXO1 and pXO2 and were infected, or not infected, with a worm intestine phage (Wip4) known to influence the phenotype and survival of the pathogen. Blood meals were prepared for the flies by inoculation of sheep blood with germinated and, in case of pXO2+ strains, encapsulated cells of the four B. anthracis strains. After being fed for 4 h an initial 10 flies were externally disinfected with peracetic acid to ensure subsequent quantitation representing ingested B. anthracis only. Following neutralization, they were crushed in sterile saline. Over each of the ensuing 7 to 10 days, 10 flies were removed and processed the same way. In the absence of Wip4, strains showed steady declines to undetectable in the total B. anthracis counts, within 7–9 days. With the phage infected strains, the falls in viable counts were significantly more rapid than in their uninfected counterparts. Spores were detectable in flies for longer periods than vegetative bacteria. In line with the findings in both biting and non-biting flies of early workers our results indicate that B. anthracis does not multiply in the guts of blow flies and survival is limited to a matter of days.This work was funded by grant BE 2157/3-1 of the German Research Foundation (DFG). SEB was funded by a United States National Institute of General Medical Sciences MIDAS grant U01GM087719 to Lauren A. Meyers and Alison P. Galvani. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Center for Computational Biology and BioinformaticsEmail: [email protected]

Når man køber en idé uden at forstå den

Denne artikel er en opfølgning på casebeskrivelsen ”Kampen om den organisatoriske selvfortælling” (find den her: https://rauli.cbs.dk/index.php/SiS/article/download/5567/6184), hvor der blev stillet en række en række spørgsmål til læserne. Artiklen her giver en række mulige svar på de stillede spørgsmål, samt en kort gennemgang af den teori, der fører frem til de givne svar

Et empirisk casestudie af omstillingsforløb i fire virksomheder

I mange virksomheder eller måske i alle virksomheder arbejder man løbende med forbedrings- og forandringsarbejder, gerne defineret som projekter med fokus på procesarbejde og de resultater, som projekterne forventes at skulle skabe....