Classification of cubic surfaces with twenty-seven lines over the finite field of order thirteen

In Hirschfeld (J Austral Math Soc 4(1):83–89, 1964), the existence of the cubic surface which arises from a double-six over the finite field of order four was considered. In Hirschfeld (Rend Mat Appl 26:115–152, 1967), the existence and the properties of the cubic surfaces over the finite fields of odd and even order was discussed and classified over the fields of order seven, eight, nine. In this paper, cubic surfaces with twenty-seven lines over the finite field of thirteen elements are classified

Availabilty of emergency care outside working hours in the province of Groningen:The role of E.R. with peripheral hospitals, ambulance services and urgent GP care

In deze rapportage wordt verslag gedaan van een onderzoek naar de bereikbaarheid van de acute zorg in Groningen. De focus lag daarbij op de acute zorg buiten kantooruren: in de avond, nacht en het weekend. Het onderzoek werd uitgevoerd door ARGO Rijksuniversiteit Groningen BV in opdracht van de samenwerkende partijen in de acute zorg, verenigd in het Regionaal Overleg Acute Zorg Groningen (ROAZ)

The closest elastic tensor of arbitrary symmetry to an elasticity tensor of lower symmetry

The closest tensors of higher symmetry classes are derived in explicit form for a given elasticity tensor of arbitrary symmetry. The mathematical problem is to minimize the elastic length or distance between the given tensor and the closest elasticity tensor of the specified symmetry. Solutions are presented for three distance functions, with particular attention to the Riemannian and log-Euclidean distances. These yield solutions that are invariant under inversion, i.e., the same whether elastic stiffness or compliance are considered. The Frobenius distance function, which corresponds to common notions of Euclidean length, is not invariant although it is simple to apply using projection operators. A complete description of the Euclidean projection method is presented. The three metrics are considered at a level of detail far greater than heretofore, as we develop the general framework to best fit a given set of moduli onto higher elastic symmetries. The procedures for finding the closest elasticity tensor are illustrated by application to a set of 21 moduli with no underlying symmetry.Comment: 48 pages, 1 figur

Serotonin and Dopamine Protect from Hypothermia/Rewarming Damage through the CBS/ H2S Pathway

Biogenic amines have been demonstrated to protect cells from apoptotic cell death. Herein we show for the first time that serotonin and dopamine increase H2S production by the endogenous enzyme cystathionine-β-synthase (CBS) and protect cells against hypothermia/rewarming induced reactive oxygen species (ROS) formation and apoptosis. Treatment with both compounds doubled CBS expression through mammalian target of rapamycin (mTOR) and increased H2S production in cultured rat smooth muscle cells. In addition, serotonin and dopamine treatment significantly reduced ROS formation. The beneficial effect of both compounds was minimized by inhibition of their re-uptake and by pharmacological inhibition of CBS or its down-regulation by siRNA. Exogenous administration of H2S and activation of CBS by Prydoxal 5′-phosphate also protected cells from hypothermic damage. Finally, serotonin and dopamine pretreatment of rat lung, kidney, liver and heart prior to 24 h of hypothermia at 3°C followed by 30 min of rewarming at 37°C upregulated the expression of CBS, strongly reduced caspase activity and maintained the physiological pH compared to untreated tissues. Thus, dopamine and serotonin protect cells against hypothermia/rewarming induced damage by increasing H2S production mediated through CBS. Our data identify a novel molecular link between biogenic amines and the H2S pathway, which may profoundly affect our understanding of the biological effects of monoamine neurotransmitters

Акционерная форма собственности: сущность и эффективность в транзитивной экономике Украины

Розкрито переваги акціонерної форми власності. Показано необхідність застосування акціонування в транзитивній економіці України