307 research outputs found

    Social Capital and Community Connections: What Matters in the Lives of Youth?

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    Social capital is seen as promoting youth success. This study analyzes all 115 counties in Missouri using correlation to determine if youth centered community connections (youth organizations, high school activities, and private schools) are related to Robert Putnam's version of social capital in communities. Multiple variable regression is used to determine what forms of community connections are associated with youth success (lower dropout rates, increased college attendance, decreased juvenile delinquency, and lower teen fertility rates). This study finds that Putnam's measure of social capital is significant in predicting teen fertility but not the other measures of youth success. High school activities was the only community connection variable associated with youth success in the form of lower dropout rates. Single parent families was the variable most associated with youth outcomes followed by median family income. Social capital and community connections do little to override family support systems and financial resources

    User Perceptions of the Environmental Quality and Governance System of Narragansett Bay

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    This paper hypothesizes that there will be differences in perception between the users and managers of Narragansett Bay with respect to (1) the Bay\u27s environmental quality; and (2) the effectiveness of the governance system established to manage and regulate the Bay. Any discrepancies in the perception of the quality of Narragansett Bay\u27s shoreline and water resources among various user groups are likely to contribute to conflicts between users, and a less efficient approach to the management of Bay resources. Thus, the identification of where management policies may diverge from the interests of public user groups will serve to improve resource management efforts and the overall governance system. The ultimate goal of this research is to provide managers and regulators with an improved understanding of resource users\u27 perceptions and needs with respect to specific management issues affecting Narragansett Bay. Such information will, in turn, result in the more effective management of the Bay and the improvement of the quality of its resources

    Track 1: Dichotomies in a STEM Course: How They Might Be Working Against Your Inclusive Strategies

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    Presentation took place May 13, 2021; presentations will be made available via WarpWire to members of the University of Dayton community in early June

    Increasing β-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis.

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    Mechanical force and Wnt signaling activate β-catenin-mediated transcription to promote proliferation and tissue expansion. However, it is unknown whether mechanical force and Wnt signaling act independently or synergize to activate β-catenin signaling and cell division. We show that mechanical strain induced Src-dependent phosphorylation of Y654 β-catenin and increased β-catenin-mediated transcription in mammalian MDCK epithelial cells. Under these conditions, cells accumulated in S/G2 (independent of DNA damage) but did not divide. Activating β-catenin through Casein Kinase I inhibition or Wnt3A addition increased β-catenin-mediated transcription and strain-induced accumulation of cells in S/G2. Significantly, only the combination of mechanical strain and Wnt/β-catenin activation triggered cells in S/G2 to divide. These results indicate that strain-induced Src phosphorylation of β-catenin and Wnt-dependent β-catenin stabilization synergize to increase β-catenin-mediated transcription to levels required for mitosis. Thus, local Wnt signaling may fine-tune the effects of global mechanical strain to restrict cell divisions during tissue development and homeostasis

    Spatial distribution of cell-cell and cell-ECM adhesions regulates force balance while main-taining E-cadherin molecular tension in cell pairs.

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    Mechanical linkage between cell-cell and cell-extracellular matrix (ECM) adhesions regulates cell shape changes during embryonic development and tissue homoeostasis. We examined how the force balance between cell-cell and cell-ECM adhesions changes with cell spread area and aspect ratio in pairs of MDCK cells. We used ECM micropatterning to drive different cytoskeleton strain energy states and cell-generated traction forces and used a Förster resonance energy transfer tension biosensor to ask whether changes in forces across cell-cell junctions correlated with E-cadherin molecular tension. We found that continuous peripheral ECM adhesions resulted in increased cell-cell and cell-ECM forces with increasing spread area. In contrast, confining ECM adhesions to the distal ends of cell-cell pairs resulted in shorter junction lengths and constant cell-cell forces. Of interest, each cell within a cell pair generated higher strain energies than isolated single cells of the same spread area. Surprisingly, E-cadherin molecular tension remained constant regardless of changes in cell-cell forces and was evenly distributed along cell-cell junctions independent of cell spread area and total traction forces. Taken together, our results showed that cell pairs maintained constant E-cadherin molecular tension and regulated total forces relative to cell spread area and shape but independently of total focal adhesion area

    Maine’s Marine Invasion (Fact Sheet)

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    What is invading Maine\u27s coastal waters? The Asian shore crab (1), Dead man\u27s fingers (2), Bonamia oyster disease (3). These are just a few of the 33 non-native species that have been documented in marine waters and shorelines along the Maine coast in a preliminary count. While many non-native species are unable to survive, reproduce, and overtake native plants and animals in Maine\u27s coastal waters, those that are successful become known as invasive species

    Suboptimal bone status for adolescents with low motor competence and developmental coordination disorder - It\u27s sex specific

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    Background: Australian adolescents with low motor competence (LMC) have higher fracture rates and poorer bone health compared to European normative data, but currently no normative data exists for Australians. Aims: To examine whether there were bone health differences in Australian adolescents with LMC or Developmental Coordination Disorder (DCD) when compared to typically developing age-matched Australian adolescents. Methods and Procedures: Australian adolescents aged 12–18 years with LMC/DCD (n=39; male=27; female=12) and an Australian comparison sample (n=188; boys=101; girls= 87) undertook radial and tibial peripheral Quantitative Computed Tomography (pQCT) scans. Stress Strain Index (SSI (mm3)), Total Bone Area (TBA (mm2)), Muscle Density (MuD [mgcm3]), Muscle Area (MuA [cm2]), Subcutaneous Fat Area (ScFA [cm2]), Cortical Density (CoD [mgcm3]), Cortical Area (CoD [mm2]), cortical concentric ring volumetric densities, Functional Muscle Bone Unit Index (FMBU: (SSI/bone length)) and Robustness Index (SSI/bone length^3), group and sex differences were examined. Outcome and Results: The main finding was a significant sex-x-group interaction for Tibial FMBU (p=.021), Radial MuD (p=.036), and radial ScFA (p=.002). Boys with LMC/DCD had lower tibial FMBU scores, radial MuD and higher ScFA than the typically developing age-matched sample. Conclusion and Implications: Comparisons of bone measures with Australian comparative data are similar to European findings however sex differences were found in the present study. Australian adolescent boys with LMC/DCD had less robust bones compared to their well-coordinated Australian peers, whereas there were no differences between groups for girls. These differences may be due to lower levels of habitual weight–bearing physical activity, which may be more distinct in adolescent boys with LMC/DCD compared to girls

    Reduced peak bone mass in young adults with low motor competence

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    Although suboptimal bone health has been reported in children and adolescents with low motor competence (LMC), it is not known whether such deficits are present at the time of peak bone mass. We examined the impact of LMC on bone mineral density (BMD) in 1043 participants (484 females) from the Raine Cohort Study. Participants had motor competence assessed using the McCarron Assessment of Neuromuscular Development at 10, 14, and 17 years, and a whole-body dual-energy X-ray absorptiometry (DXA) scan at 20 years. Bone loading from physical activity was estimated from the International Physical Activity Questionnaire at the age of 17 years. The association between LMC and BMD was determined using general linear models that controlled for sex, age, body mass index, vitamin D status, and prior bone loading. Results indicated LMC status (present in 29.6% males and 21.9% females) was associated with a 1.8% to 2.6% decrease in BMD at all load-bearing bone sites. Assessment by sex showed that the association was mainly in males. Osteogenic potential of physical activity was associated with increased BMD dependent on sex and LMC status, with males with LMC showing a reduced effect from increasing bone loading. As such, although engagement in osteogenic physical activity is associated with BMD, other factors involved in physical activity, eg, diversity, movement quality, may also contribute to BMD differences based upon LMC status. The finding of lower peak bone mass for individuals with LMC may reflect a higher risk of osteoporosis, especially for males; however, further research is required

    Missing the forest because of the trees : Slower alternations during binocular rivalry are associated with lower levels of visual detail during ongoing thought

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    Conscious awareness of the world fluctuates, either through variation in how vividly we perceive the environment, or when our attentional focus shifts away from information in the external environment towards information that we generate via imagination. Our study combined individual differences in experience sampling, psychophysical reports of perception, and neuroimaging descriptions of structural connectivity to better understand these changes in conscious awareness. In particular, we examined (1) whether aspects of ongoing thought—indexed via multi-dimensional experience sampling during a sustained-attention task—are associated with the white-matter fibre organization of the cortex as reflected by their relative degree of anisotropic diffusion, and (2) whether these neuro-cognitive descriptions of ongoing experience are related to a more constrained measure of visual consciousness through analysis of bi-stable perception during binocular rivalry. Individuals with greater fractional anisotropy in right hemisphere white-matter regions involving the inferior fronto-occipital fasciculus, the superior longitudinal fasciculus, and the cortico-spinal tract, described their ongoing thoughts as lacking external details. Subsequent analysis indicated that the combination of low fractional anisotropy in these right hemisphere regions, with reports of thoughts with high-levels of external details, was associated with the shortest periods of dominance during binocular rivalry. Since variation in binocular rivalry reflects differences between bottom-up and top-down influences on vision, our study suggests that reports of ongoing thoughts with vivid external details may occur when conscious precedence is given to bottom-up representation of perceptual information

    Changes in Depression and Stress after Release from a Tobacco-Free Prison in the United States

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    Prior research has found high levels of depression and stress among persons who are incarcerated in the United States (U.S.). However, little is known about changes in depression and stress levels among inmates post-incarceration. The aim of this study was to examine changes in levels of depression and stress during and after incarceration in a tobacco-free facility. Questionnaires that included valid and reliable measures of depression and stress were completed by 208 male and female inmates approximately eight weeks before and three weeks after release from a northeastern U.S. prison. Although most inmates improved after prison, 30.8% had a worsening in levels of depression between baseline and the three-week follow-up. In addition, 29.8% had a worsening in levels of stress after release than during incarceration. While it is not surprising that the majority of inmates reported lower levels of depression and stress post-incarceration, a sizable minority had an increase in symptoms, suggesting that environmental stressors may be worse in the community than in prison for some inmates. Further research is needed to address depression and stress levels during and after incarceration in order for inmates to have a healthier transition back into the community and to prevent repeat incarcerations
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