Hemangiopericytomas of the spine: case report and review of the literature

We describe a rare case of a primary intracranial meningeal hemangiopericytoma (HPC) with late metastasis to the cervical spine. A 36-year-old woman had a left occipital lesion that was histopathologically identified as HPC. Fourteen years after resection, the tumor recurred and was treated with radiotherapy. Three years later, CT imaging showed a large mass in the liver consistent with metastatic HPC, and MRI of the cervical spine showed an extensive lesion of the C3 vertebral body. The patient underwent C3 corpectomy with en-bloc tumor removal and follow-up radiation with no local recurrence or other spinal metastasis for the following 4 years. Regardless of the subtype of spinal HPC, complete surgical removal and radiotherapy appear to be treatment of choice

Nonviral Approaches for Neuronal Delivery of Nucleic Acids

The delivery of therapeutic nucleic acids to neurons has the potential to treat neurological disease and spinal cord injury. While select viral vectors have shown promise as gene carriers to neurons, their potential as therapeutic agents is limited by their toxicity and immunogenicity, their broad tropism, and the cost of large-scale formulation. Nonviral vectors are an attractive alternative in that they offer improved safety profiles compared to viruses, are less expensive to produce, and can be targeted to specific neuronal subpopulations. However, most nonviral vectors suffer from significantly lower transfection efficiencies than neurotropic viruses, severely limiting their utility in neuron-targeted delivery applications. To realize the potential of nonviral delivery technology in neurons, vectors must be designed to overcome a series of extra- and intracellular barriers. In this article, we describe the challenges preventing successful nonviral delivery of nucleic acids to neurons and review strategies aimed at overcoming these challenges

Mouvement de l'eau dans le sol (Suite).

Betchen G. Mouvement de l'eau dans le sol (Suite).. In: Revue de botanique appliquée et d'agriculture coloniale, 12ᵉ année, bulletin n°128, avril 1932. pp. 291-295

Mouvement de l'Eau dans le sol.

Betchen G. Mouvement de l'Eau dans le sol.. In: Revue de botanique appliquée et d'agriculture coloniale, 12ᵉ année, bulletin n°127, mars 1932. pp. 180-188

Mouvement de l'eau dans le sol (Fin).

Betchen G. Mouvement de l'eau dans le sol (Fin).. In: Revue de botanique appliquée et d'agriculture coloniale, 12ᵉ année, bulletin n°129, mai 1932. pp. 358-372