Beyond thermal comfort in the hospital rooms. Investigation of thermal summer comfort in patients rooms: case of Biskra hospitals

In Algeria, the architectural design of hospitals is unfortunately not subject to clear and specific regulatory thermal strategy, it depends mainly on the architect own approach to the issue of comfort design, materials, etc. This research aims to investigate the present comfort conditions in typical hospital configuration and under specific climate conditions of hot and arid regions. Two different hospital designs have been investigated in Biskra. A main town is southeast of Algeria. The first case study being the oldest hospital in the town, build in the late 30s during the colonial era and renovated recently. The second hospital is a brand new hospital. A series of measurements of ambient air temperature, patient surveys and interviews have been initiated in two typical wards. The results show that thermal comfort sensations in these specific spaces depend not only on architecture, design and typical processes, but also on physiological, psychological and behavioral parameters which widely influence the perception of the patients

Hematological features in children with systemic lupus erythematosus: are they more common than appreciated?

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The role of clinical pilates exercises in children wıth juvenile idiopathic arthritis: a pilot study

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Genotoxicity of anti-tumor necrosis factor therapy in patients with juvenile idiopathic arthritis

Objective. To assess the possible effects of both inflammation and the anti-tumor necrosis factor agents (anti-TNF) on DNA damage with a specific assay, and their effects on the repair capacity of DNA. Methods. From a group of 20 children with juvenile idiopathic arthritis (JIA), 16 patients who completed the study and 16 control subjects were evaluated. DNA damage and repair capacity were analyzed by the comet assay at the level of peripheral lymphocytes before anti-TNF (etanercept) injections and on the 15th, 90th, and 180th days after the first injection. Results. The amount of damage as detected by the aforementioned assay was higher in patients with JIA compared with controls. On the 15th day after the initial anti-TNF injection, there was a decrease in the mean DNA tail length of JIA patients, however on the 90th day an increase was observed; thereafter, an upward trend was observed until the end of the study. JIA patients had a DNA repair capacity that was significantly less than that of controls. Conclusion. The results of the comet technique suggests that JIA patients already have increased basal DNA damage before anti-TNF therapy; they are more sensitive to the DNA damage produced by H 2O 2, and have a less efficient DNA repair system in comparison with control cells. After an initial improvement at 2 weeks, parameters of genotoxicity worsened, and DNA repair was further impaired 6 months after the addition of an anti-TNF agent to treatment. © 2010, American College of Rheumatology

A safe protocol for tuberculin test assessment in a country where BCG vaccination is mandatory

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Does unity of Familial Mediterranean fever with juvenile idiopathic arthritis affect the outcome?

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A pilot study for genome wide association study (GWAS) in patients with juvenile idiopathic arthritis (JIA) and their parents

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Au4Mn, a localized ferromagnet with strong spin-orbit coupling, long-range ferromagnetic exchange and high Curie temperature

Metallic Mn-based alloys with a nearest-neighbor Mn-Mn distance greater than 0.4 nm exhibit large, well-localized magnetic moments. Here we investigate the magnetism of tetragonal Au4Mn with a Curie temperature of 385 K, where manganese has a spin moment of 4.1 muB and its orbital moment is quenched. Since 80% of the atoms are gold, the spin orbit interaction is strong and Au4Mn exhibits uniaxial magnetocrystalline anisotropy with surface maze domains at room temperature. The magnetic hardness parameter of 1.0 is sufficient to maintain the magnetization along the c-axis for a sample of any shape. Au also reduces the spin moment of Mn through 5d-3d orbital hybridization. An induced moment of 0.05 muB was found on Au under a pulsed field of 40 T. Density functional theory calculations indicate that the Mn-Mn exchange is mediated by spin-polarized gold 5d and 6p electrons. The distance-dependence shows that it is ferromagnetic or zero for the first ten shells of Mn neighbors out to 1.041 nm (64 atoms), and very weak and oscillatory thereafter