Russia and "hybrid warfare"

In the aftermath of the Crimea annexation in March 2014, the idea of ‘hybrid warfare’ quickly gained prominence as a concept that could help to explain the success of Russian military operations in this conflict. Although the concept continues to enjoy widespread popularity in both scholarly and policy circles, its utility as an analytical tool is also heavily contested. This article adds to the literature critical of the ‘hybrid warfare’ concept. It argues that in addition to the fact that what is now described as a ‘hybrid’ approach to war is in fact nothing new, the problems pertaining to its utility for the study of contemporary Russia go deeper than this. ‘Hybrid warfare’ inadequately reflects the direction of Russian military modernisation and as such has led to a skewed understanding of Russian military capabilities. Moreover, the tendency to use ‘hybrid warfare’ not only to conceptualise developments in the Russian military, but in the country’s foreign policy in general, can lead to serious unintended consequences

Assessment study of spectro-polarimeter concepts based on Fabry-Perot cavities and nano-structures

In this paper, we present an assessment study of the performances of a spectropolarimeter based on Fabry-Perot cavities and nano-structures. This technology allows a substantial reduction in complexity and volume of current state-of-the-art instruments thanks to the integration of spectral and polarimetric filters on the detector array

Application of Low-Frequency Raman Scattering Spectroscopy to Probe in Situ Drug Solubilization in Milk during Digestion

We have recently shown that real-time monitoring of drug solubilization and changes to solid state of the drug during digestion of milk can be achieved using synchrotron small-angle X-ray scattering. A complementary laboratory-based method to explore such changes is low-frequency Raman spectroscopy, which has been increasingly used to characterize crystalline drugs and their polymorphs in powders and suspensions. This study investigates the use of this technique to monitor in situ drug solubilization in milk during the process of digestion, using a lipolysis model/flow-through configuration identical to that used previously for in situ synchrotron small-angle X-ray scattering studies. An antimalarial drug, ferroquine (SSR97193), was used as the model drug for this study. The Raman spectra were processed using multivariate analysis to extract the drug signals from the milk digestion background. The results showed disappearance of the ferroquine peaks in the low-frequency Raman region (<200 cm–1) after approximately 15–20 min of digestion when milk fat was present in the system, which indicated drug solubilization and was in good agreement with the in situ small-angle X-ray scattering measurements. This proof-of-concept study therefore suggests that low-frequency Raman spectroscopy can be used to monitor drug solubilization in a complex digesting milk medium because of the unique vibrational modes of the drug crystal lattices