2,008 research outputs found
Knowledge management : a learning mix perspective
How can an organization define policy for managing its knowledge ? In this article, an integrative model is proposed : the Learning Mix. It consists of 4 interacting facets: Information Technology, Learning Structure, Knowledge Portfolio and Learning Identity.knowledge management; learning; learning model
Latin hypercube sampling with inequality constraints
In some studies requiring predictive and CPU-time consuming numerical models,
the sampling design of the model input variables has to be chosen with caution.
For this purpose, Latin hypercube sampling has a long history and has shown its
robustness capabilities. In this paper we propose and discuss a new algorithm
to build a Latin hypercube sample (LHS) taking into account inequality
constraints between the sampled variables. This technique, called constrained
Latin hypercube sampling (cLHS), consists in doing permutations on an initial
LHS to honor the desired monotonic constraints. The relevance of this approach
is shown on a real example concerning the numerical welding simulation, where
the inequality constraints are caused by the physical decreasing of some
material properties in function of the temperature
HRF estimation improves sensitivity of fMRI encoding and decoding models
Extracting activation patterns from functional Magnetic Resonance Images
(fMRI) datasets remains challenging in rapid-event designs due to the inherent
delay of blood oxygen level-dependent (BOLD) signal. The general linear model
(GLM) allows to estimate the activation from a design matrix and a fixed
hemodynamic response function (HRF). However, the HRF is known to vary
substantially between subjects and brain regions. In this paper, we propose a
model for jointly estimating the hemodynamic response function (HRF) and the
activation patterns via a low-rank representation of task effects.This model is
based on the linearity assumption behind the GLM and can be computed using
standard gradient-based solvers. We use the activation patterns computed by our
model as input data for encoding and decoding studies and report performance
improvement in both settings.Comment: 3nd International Workshop on Pattern Recognition in NeuroImaging
(2013
Brain covariance selection: better individual functional connectivity models using population prior
Spontaneous brain activity, as observed in functional neuroimaging, has been
shown to display reproducible structure that expresses brain architecture and
carries markers of brain pathologies. An important view of modern neuroscience
is that such large-scale structure of coherent activity reflects modularity
properties of brain connectivity graphs. However, to date, there has been no
demonstration that the limited and noisy data available in spontaneous activity
observations could be used to learn full-brain probabilistic models that
generalize to new data. Learning such models entails two main challenges: i)
modeling full brain connectivity is a difficult estimation problem that faces
the curse of dimensionality and ii) variability between subjects, coupled with
the variability of functional signals between experimental runs, makes the use
of multiple datasets challenging. We describe subject-level brain functional
connectivity structure as a multivariate Gaussian process and introduce a new
strategy to estimate it from group data, by imposing a common structure on the
graphical model in the population. We show that individual models learned from
functional Magnetic Resonance Imaging (fMRI) data using this population prior
generalize better to unseen data than models based on alternative
regularization schemes. To our knowledge, this is the first report of a
cross-validated model of spontaneous brain activity. Finally, we use the
estimated graphical model to explore the large-scale characteristics of
functional architecture and show for the first time that known cognitive
networks appear as the integrated communities of functional connectivity graph.Comment: in Advances in Neural Information Processing Systems, Vancouver :
Canada (2010
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