1,431 research outputs found

    Reflection Impacts Preservice Teachers Instruction and Planning

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    Access the online Pressbooks version of this article here. Creating a habit of reflective practice promotes ongoing and sustainable instructional improvement for preservice teachers. Furthermore, reflection enables teachers to strengthen their instruction through critical analysis of student learning and engagement. While reflection may be intuitive for an in-service teacher, preservice teachers need this experience to develop intentional and automatic reflective practice. Adopted from the field of medicine, Subjective, Observation, Assessment, Planning (SOAP) Notes is a reflective strategy that allows educators to critically reflect on the lessons they have taught. SOAP Notes promote critical reflection on planning and student learning and may impact classroom management and instructional decision-making

    Toll like Receptor signalling by Prevotella histicola activates alternative NF-κB signalling in Cystic Fibrosis bronchial epithelial cells compared to P. aeruginosa.

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    Funder: Department for Employment and Learning, Northern Ireland, UK; Grant(s): (https://www.nidirect.gov.uk/articles/department-economy-studentships)Funder: Northern Ireland Chest, Heart and Stroke Association, UK; Grant(s): NICHS, 2014_15 (https://www.nicva.org/organisation/ni-chest-heart-stroke)Cystic Fibrosis (CF), caused by mutations affecting the CFTR gene, is characterised by viscid secretions in multiple organ systems. CF airways contain thick mucus, creating a gradient of hypoxia, which promotes the establishment of polymicrobial infection. Such inflammation predisposes to further infection, a self-perpetuating cycle in mediated by NF-κB. Anaerobic Gram-negative Prevotella spp. are found in sputum from healthy volunteers and CF patients and in CF lungs correlate with reduced levels of inflammation. Prevotella histicola (P. histicola) can suppress murine lung inflammation, however, no studies have examined the role of P. histicola in modulating infection and inflammation in the CF airways. We investigated innate immune signalling and NF-kB activation in CF epithelial cells CFBE41o- in response to clinical stains of P. histicola and Pseudomonas aeruginosa (P. aeruginosa). Toll-Like Receptor (TLR) expressing HEK-293 cells and siRNA assays for TLRs and IKKα were used to confirm signalling pathways. We show that P. histicola infection activated the alternative NF-kB signalling pathway in CF bronchial epithelial cells inducing HIF-1α protein. TLR5 signalling was responsible for the induction of the alternative NF-kB pathway through phosphorylation of IKKα. The induction of transcription factor HIF-1α was inversely associated with the induction of the alternative NF-kB pathway and knockdown of IKKα partially restored canonical NF-kB activation in response to P. histicola. This study demonstrates that different bacterial species in the respiratory microbiome can contribute differently to inflammation, either by activating inflammatory cascades (P. aeruginosa) or by muting the inflammatory response by modulating similar or related pathways (P. histicola). Further work is required to assess the complex interactions of the lung microbiome in response to mixed bacterial infections and their effects in people with CF

    Reflection Impacts Preservice Teachers\u27 Instruction and Planning

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    Creating a habit of reflective practice promotes ongoing and sustainable instructional improvement for preservice teachers. Furthermore, reflection enables teachers to strengthen their instruction through critical analysis of student learning and engagement. While reflection may be intuitive for an in-service teacher, preservice teachers need this experience to develop intentional and automatic reflective practice. Adopted from the field of medicine, Subjective, Observation, Assessment, Planning (SOAP) Notes is a reflective strategy that allows educators to critically reflect on the lessons they have taught. SOAP Notes promote critical reflection on planning and student learning and may impact classroom management and instructional decision-making

    Gut bacteria and necrotizing enterocolitis: cause or effect?

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    Development of necrotising enterocolitis (NEC) is considered to be dependent on the bacterial colonisation of the gut. With little concordance between published data and a recent study failing to detect a common strain in infants with NEC, more questions than answers are arising about our understanding of this complex disease

    Periodic orbit analysis of an elastodynamic resonator using shape deformation

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    We report the first definitive experimental observation of periodic orbits (POs) in the spectral properties of an elastodynamic system. The Fourier transform of the density of flexural modes show peaks that correspond to stable and unstable POs of a clover shaped quartz plate. We change the shape of the plate and find that the peaks corresponding to the POs that hit only the unperturbed sides are unchanged proving the correspondence. However, an exact match to the length of the main POs could be made only after a small rescaling of the experimental results. Statistical analysis of the level dynamics also shows the effect of the stable POs.Comment: submitted to Europhysics Letter

    Through the Eyes of the Mentor: Understanding the Adolescent Developing Reader

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    While some teacher candidates may believe reading instruction is the responsibility of English teachers, providing teacher candidates across all content areas with opportunities to develop skills working with developing readers may impact this misconception. Since some teacher candidates have limited experience, confidence, and/or reading strategies to instruct developing readers, this study examines the individual experiences of reading mentors at a midwestern university and the effect of their experience on developing readers. This mentoring experience revealed an impact both for the teacher candidates and developing readers. This opportunity proved to be rewarding while providing a glimpse of the reality of working with developing readers in teacher candidates’ future classrooms

    Through the Eyes of the Mentor: Understanding the Adolescent Developing Reader

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    While some teacher candidates may believe reading instruction is the responsibility of English teachers, providing teacher candidates across all content areas with opportunities to develop skills working with developing readers may impact this misconception. Since some teacher candidates have limited experience, confidence, and/or reading strategies to instruct developing readers, this study examines the individual experiences of reading mentors at a midwestern university and the effect of their experience on developing readers. This mentoring experience revealed an impact both for the teacher candidates and developing readers. This opportunity proved to be rewarding while providing a glimpse of the reality of working with developing readers in teacher candidates’ future classrooms

    Distinct nature of static and dynamic magnetic stripes in cuprate superconductors

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    We present detailed neutron scattering studies of the static and dynamic stripes in an optimally doped high-temperature superconductor, La2_2CuO4+y_{4+y}. We find that the dynamic stripes do not disperse towards the static stripes in the limit of vanishing energy transfer. We conclude that the dynamic stripes observed in neutron scattering experiments are not the Goldstone modes associated with the broken symmetry of the simultaneously observed static stripes, but rather that the signals originate from different domains in the sample. These domains may be related by structural twinning, or may be entirely different phases, where the static stripes in one phase are pinned versions of the dynamic stripes in the other. Our results explain earlier observations of unusual dispersions in underdoped La2x_{2-x}Srx_xCuO4_{4} (x=0.07x=0.07) and La2x_{2-x}Bax_xCuO4_{4} (x=0.095x=0.095). Our findings are relevant for all compounds exhibiting magnetic stripes, and may thus be a vital part in unveiling the nature of high temperature superconductivity

    Providing Hope after Trauma: Educating in a Juvenile Residential Center

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    The field of integrated language arts is an ideal forum for sharing stories, discussing perspectives, expressing emotions in a healthy way, and challenging the systems that govern and shape our lives. Accomplishing this goal in a traditional classroom can sometimes be difficult, but for a moment, consider the physical space of a classroom within a juvenile residential center (JRC). This space brings many obstacles that traditional classrooms, teachers, and students do not have to address. To thrive, students need to be in a safe environment of trust. Trust is both critical and challenging to build in a space with so many limitations. By centering student agency, identity, and awareness of structural barriers, teachers may be able to make a positive difference in the lives of incarcerated students, especially those impacted by trauma. This could help students gain a new perspective on their own recidivism and cycles underneath a systemic context, hopefully forging a path toward freedom and healing. This qualitative case study focuses on two novice teachers’ journeys as they navigate their instructional decisions and practice within a JRC
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