Abating Prejudice With Presence: Dispositional Mindfulness Increases Interracial Helping Behavior

Helping behavior is less frequently shown toward members of social out-groups (Cikra, Bruneau, & Saxe, 2011). Race defines a common source of social division in America and other countries, and although most condemn racial discrimination, helping is undermined in interracial interactions (Saucier, Miller, & Doucet, 2005). Recent theory suggests that mindfulness, a receptive attention to one’s present experience, can attenuate the conceptual boundaries that typically separate and distance oneself from others (Trautwein, Schmidt, & Naranjo, 2014). We designed an experiment to examine whether dispositional mindfulness would be associated with increased helping behavior in interracial contexts. Self-identifying White participants (N = 139) witnessed a confederate in need of help while waiting to participate in a study, and experimenters observed whether participants helped them or not; self-identifying White or Black confederates were randomly assigned to each experimental session. Three-block sequential logistic regression models were constructed to identify predictors of same-race and interracial helping. Overall, dispositional mindfulness, agreeableness, and lower racial prejudice predicted greater helping behavior in same-race interactions (all ps \u3c 0.05). Interestingly, mindfulness moderated the help-reducing effects of racial prejudice in the interracial interactions (p \u3c 0.05). More specifically, high mindfulness was associated with increased helping behavior among those high in racial prejudice. This correlational evidence is consistent with mindfulness theory, which suggests deploying mindful attention dampens psychological barriers between self and others. This study highlights the potential for mindfulness in reducing defensive attitudes and increasing prosocial responsiveness across social lines.https://scholarscompass.vcu.edu/uresposters/1230/thumbnail.jp

Graduate Credit for Industrial Arts Shopwork in Colleges and Universities of the United States

Industrial Arts Education and Engineerin

Sidechain control of porosity closure in multiple peptide-based porous materials by cooperative folding

Porous materials find application in separation, storage and catalysis. We report a crystalline porous solid formed by coordination of metal centres with a glycylserine dipeptide. We prove experimentally that the structure evolves from a solvated porous into a non-porous state as result of ordered displacive and conformational changes of the peptide that suppress the void space in response to environmental pressure. This cooperative closure, which recalls the folding of proteins, retains order in three-dimensions and is driven by the hydroxyl groups acting as H-bond donors in the peptide sequence through the serine residue. This ordered closure is also displayed by multipeptide solid solutions in which the combination of different sequences of amino acids controls their guest response in a non-linear way. This functional control can be compared to the effect of single point mutations in proteins, where the exchange of single amino acids can radically alter structure and functio

Effects of siRNA-mediated knockdown of GSK3β on retinal ganglion cell survival and neurite/axon growth

There are contradictory reports on the role of the serine/threonine kinase isoform glycogen synthase kinase-3β (GSK3β) after injury to the central nervous system (CNS). Some report that GSK3 activity promotes axonal growth or myelin disinhibition, whilst others report that GSK3 activity prevents axon regeneration. In this study, we sought to clarify if suppression of GSK3β alone and in combination with the cellular-stress-induced factor RTP801 (also known as REDD1: regulated in development and DNA damage response protein), using translationally relevant siRNAs, promotes retinal ganglion cell (RGC) survival and neurite outgrowth/axon regeneration. Adult mixed retinal cell cultures, prepared from rats at five days after optic nerve crush (ONC) to activate retinal glia, were treated with siRNA to GSK3β (siGSK3β) alone or in combination with siRTP801 and RGC survival and neurite outgrowth were quantified in the presence and absence of Rapamycin or inhibitory Nogo-A peptides. In in vivo experiments, either siGSK3β alone or in combination with siRTP801 were intravitreally injected every eight days after ONC and RGC survival and axon regeneration was assessed at 24 days. Optimal doses of siGSK3β alone promoted significant RGC survival, increasing the number of RGC with neurites without affecting neurite length, an effect that was sensitive to Rapamycin. In addition, knockdown of GSK3β overcame Nogo-A-mediated neurite growth inhibition. Knockdown of GSK3β after ONC in vivo enhanced RGC survival but not axon number or length, without potentiating glial activation. Knockdown of RTP801 increased both RGC survival and axon regeneration, whilst the combined knockdown of GSK3β and RTP801 significantly increased RGC survival, neurite outgrowth, and axon regeneration over and above that observed for siGSK3β or siRTP801 alone. These results suggest that GSK3β suppression promotes RGC survival and axon initiation whilst, when in combination with RTP801, it also enhanced disinhibited axon elongation

Design of 9-meter carbon-fiberglass prototype blades : CX-100 and TX-100 : final project report.

TPI Composites, Inc. (TPI), Global Energy Concepts, LLC (GEC), and MDZ Consulting (MDZ) have collaborated on a project to design, manufacture, and test prototype carbon-fiberglass hybrid wind turbine blades of 9-m length. The project, funded by Sandia National Laboratories, involves prototype blades in both conventional (unidirectional spar fibers running along the blade span) and ''adaptive'' (carbon fibers in off-axis orientation to achieve bend-twist-coupling) configurations. After manufacture, laboratory testing is being conducted to determine the static and fatigue strength of the prototypes, in conjunction with field testing to evaluate the performance under operational conditions