Telegram from South Dakota Governor Tom Berry replying to Governor Langer\u27s telegram of 5 August Concerning a Minimum Price for Grain, 1933

South Dakota Tom Berry\u27s reply to Gov William Langer\u27s telegram of 5 August regarding the price of Grain. Berry urges waiting until the Farm Credit Administration\u27s allotment plan for stabilizing farm product prices has gone into effect before making further suggestions.https://commons.und.edu/langer-papers/1049/thumbnail.jp

How to diagnose and manage angina without obstructive coronary artery disease: Lessons from the British Heart Foundation CorMicA trial

Patients with symptoms and/or signs of ischaemia but no obstructive coronary artery disease (INOCA) present a diagnostic and therapeutic challenge. Microvascular and/or vasospastic angina are the two most common causes of INOCA; however, invasive coronary angiography lacks the sensitivity to diagnose these functional coronary disorders. In this article, the authors summarise the rationale for invasive testing in the absence of obstructive coronary disease, namely that correct treatment for angina patients starts with the correct diagnosis. They provide insights from the CORonary MICrovascular Angina (CorMicA) study, where an interventional diagnostic procedure was performed with linked medical therapy to improve patient health. Identification of these distinct disorders (microvascular angina, vasospastic angina or non-cardiac chest pain) is key for stratifying INOCA patients, allowing prognostic insights and better patient care with linked therapy based on contemporary guidelines. Finally, they propose a framework to diagnose and manage patients in this common clinical scenario

S2_5 Immortal Mice

The constant changing of batteries in wireless computer mice is an endless problem that plagues both computer enthusiasts and the general public alike. We explore the idea of having a dynamo built into a wireless mouse and seeing if it is able to offset the battery usage of the mouse. We calculated that the dynamo would need an emf of 0.0018V to maintain the battery charge. We took 0.050T as the point where components would be damaged by the magnetic field, and from this we saw that the dynamo would only be viable to gamers and not the general public

Structural and biophysical analysis of the CLCA1 VWA domain suggests mode of TMEM16A engagement

The secreted protein calcium-activated chloride channel regulator 1 (CLCA1) utilizes a von Willebrand factor type A (VWA) domain to bind to and potentiate the calcium-activated chloride channel TMEM16A. To gain insight into this unique potentiation mechanism, we determined the 2.0-Å crystal structure of human CLCA1 VWA bound to C

S2_1 Getting comfortable on Neptune

The effects of long term exposure to high gravity on human health are not well understood but will likely prove to be problematic. Therefore, if humans wish to colonise planets with signicantly higher gravity than Earth then it may be necessary to engineer solutions to articially reduce the effects of gravity. This paper assesses the admittedly elaborate idea to use the centrifugal and Coriolis effects to articially reduce the effects of gravity through increasing a planet's rotation. We decided to use Neptune as an example but the concepts and maths used in this paper should be applicable to any planet. We worked out that we would need to speed up Neptune's rotation by 6.12*10-5rads-1 to simulate a downwards acceleration of 9ms-2 at the equator and that this would require an impulse of 6.2*1028Ns

S2_2 Astronomical Tidal Energy

If the Earth ever found itself in the unlikely situation of suddenly orbiting an intermediate black hole of mass 1*103 mass of the sun [1], a large problem we would face would be the lack of heat that we originally received from the sun through solar energy. An avenue of hope for our problem would be to see if the tidal energy produced by the black hole would be enough to match the energy that we would receive from the sun, which is 1.74*1017W [2]. We decided to use an intermediate black hole as an example but the concepts and maths used in this paper should be applicable to any black hole. The output of the tidal energy was calculated to be 1.47*107W which is a factor of over a billion times smaller than what we receive from the sun. This would mean that the Earth would be unable to maintain its current surface temperature resulting in life being exposed to a colder and more hostile environment

S2_4 Stumbling Stormtroopers

Lasers rifes are a common choice of weaponry in the Star Wars franchise. In the opening sceneof 'A new hope', a stormtrooper is hit by a lasers and is forced backwards. This, as well asseveral other scenes imply that lasers have signicant momentum in Star Wars. This providedthe inspiration to work out the momentum and energy contained in a single laser blast, thensubsequently analyse the properties of the armour in Star Wars. The energy of a laser blast wascalculated to be 1.2*1011J and the properties of armour were assessed as a function of specicheat capacity and mass in figure (2). From this, it was concluded that either the materials in Star Wars are vastly dierent from Earth materials or that Star Wars laser rifes are not actually lasers