331 research outputs found
Price Markups, Innovation, and Productivity: Evidence from Germany. Bertelsmann Stiftung July 2020.
Productivity is seen as a driving force behind economic
growth and an indicator of a society’s material wellbeing.
Over the past decades, however, many industrialized
countries have experienced declining productivity growth
and an expansion of the productivity differential. Possible
explanations range from declining investment in R & D
to structural changes to more services and increased
measurement errors due to increasing digitalization.
In this report, we study the role that a firm’s competitive
environment plays for its own productivity development.
Is an increase in industry concentration – and the
expected decrease in competition – associated with lower
productivity? And what is the underlying driving force of
this effect?
Our findings of relatively strong direct effects of price
markups (in comparison to the innovation-centered
indirect effects) in all sectors but services highlight the
potential for a well-tailored competition policy approach
in society’s effort to tackle the productivity slowdown.
This is particularly true for the trade sector, where the
effect of competition on R & D and innovation is of limited
significance for the determination of firm-level productivity. For services, on the other hand, the interdependence of competition and innovation in their effect on productivity must be taken into account as the indirect effect partially offsets the direct effect of competition on productivity. Considering one without the other will be misguiding
Association of perinatal sentinel events, placental pathology and cerebral MRI in neonates with hypoxic-ischemic encephalopathy receiving therapeutic hypothermia
OBJECTIVE: Placental pathology might provide information on the etiology of hypoxic-ischemic encephalopathy (HIE). To evaluate the association of perinatal sentinel events (PSE), placental pathology and cerebral MRI in cooled neonates with moderate/severe HIE.
STUDY DESIGN: Retrospective analysis of 52 neonates with HIE registered in the Swiss National Asphyxia and Cooling Register 2011-2019. PSE and Non-PSE groups were tested for association with placental pathology. Placental pathology categories were correlated with MRI scores.
RESULTS: In total, 14/52 neonates (27%) had a PSE, 38 neonates (73%) did not have a PSE. There was no evidence for an association of occurrence of PSE and placental pathologies (p = 0.364). Neonates with high MRI scores tended to have more often chronic pathologies in their placentas than acute pathologies or normal placentas (p = 0.067).
CONCLUSION: Independent of the occurrence of PSE, chronic placental pathologies might be associated with more severe brain injury and needs further study
Determining neutrino oscillation parameters from atmospheric muon neutrino disappearance with three years of IceCube DeepCore data
We present a measurement of neutrino oscillations via atmospheric muon
neutrino disappearance with three years of data of the completed IceCube
neutrino detector. DeepCore, a region of denser instrumentation, enables the
detection and reconstruction of atmospheric muon neutrinos between 10 GeV and
100 GeV, where a strong disappearance signal is expected. The detector volume
surrounding DeepCore is used as a veto region to suppress the atmospheric muon
background. Neutrino events are selected where the detected Cherenkov photons
of the secondary particles minimally scatter, and the neutrino energy and
arrival direction are reconstructed. Both variables are used to obtain the
neutrino oscillation parameters from the data, with the best fit given by
and
(normal mass hierarchy assumed). The
results are compatible and comparable in precision to those of dedicated
oscillation experiments.Comment: 10 pages, 7 figure
A combined maximum-likelihood analysis of the high-energy astrophysical neutrino flux measured with IceCube
Evidence for an extraterrestrial flux of high-energy neutrinos has now been
found in multiple searches with the IceCube detector. The first solid evidence
was provided by a search for neutrino events with deposited energies
TeV and interaction vertices inside the instrumented volume. Recent
analyses suggest that the extraterrestrial flux extends to lower energies and
is also visible with throughgoing, -induced tracks from the Northern
hemisphere. Here, we combine the results from six different IceCube searches
for astrophysical neutrinos in a maximum-likelihood analysis. The combined
event sample features high-statistics samples of shower-like and track-like
events. The data are fit in up to three observables: energy, zenith angle and
event topology. Assuming the astrophysical neutrino flux to be isotropic and to
consist of equal flavors at Earth, the all-flavor spectrum with neutrino
energies between 25 TeV and 2.8 PeV is well described by an unbroken power law
with best-fit spectral index and a flux at 100 TeV of
.
Under the same assumptions, an unbroken power law with index is disfavored
with a significance of 3.8 () with respect to the best
fit. This significance is reduced to 2.1 () if instead we
compare the best fit to a spectrum with index that has an exponential
cut-off at high energies. Allowing the electron neutrino flux to deviate from
the other two flavors, we find a fraction of at Earth.
The sole production of electron neutrinos, which would be characteristic of
neutron-decay dominated sources, is rejected with a significance of 3.6
().Comment: 16 pages, 10 figures; accepted for publication in The Astrophysical
Journal; updated one referenc
The IceCube Neutrino Observatory - Contributions to ICRC 2015 Part II: Atmospheric and Astrophysical Diffuse Neutrino Searches of All Flavors
Papers on atmospheric and astrophysical diffuse neutrino searches of all
flavors submitted to the 34th International Cosmic Ray Conference (ICRC 2015,
The Hague) by the IceCube Collaboration.Comment: 66 pages, 36 figures, Papers submitted to the 34th International
Cosmic Ray Conference, The Hague 2015, v2 has a corrected author lis
Flavor Ratio of Astrophysical Neutrinos above 35 TeV in IceCube
A diffuse flux of astrophysical neutrinos above has been
observed at the IceCube Neutrino Observatory. Here we extend this analysis to
probe the astrophysical flux down to and analyze its flavor
composition by classifying events as showers or tracks. Taking advantage of
lower atmospheric backgrounds for shower-like events, we obtain a shower-biased
sample containing 129 showers and 8 tracks collected in three years from 2010
to 2013. We demonstrate consistency with the
flavor ratio at Earth
commonly expected from the averaged oscillations of neutrinos produced by pion
decay in distant astrophysical sources. Limits are placed on non-standard
flavor compositions that cannot be produced by averaged neutrino oscillations
but could arise in exotic physics scenarios. A maximally track-like composition
of is excluded at , and a purely shower-like
composition of is excluded at .Comment: 8 pages, 3 figures. Submitted to PR
Apheresis therapies for NMOSD attacks A retrospective study of 207 therapeutic interventions
Objective To analyze whether 1 of the 2 apheresis techniques, therapeutic plasma exchange (PE) or immunoadsorption (IA), is superior in treating neuromyelitis optica spectrum disorder (NMOSD) attacks and to identify predictive factors for complete remission (CR). Methods This retrospective cohort study was based on the registry of the German Neuromyelitis Optica Study Group, a nationwide network established in 2008. It recruited patients with neuromyelitis optica diagnosed according to the 2006 Wingerchuk criteria or with aquaporin-4 (AQP4-ab)-antibody-seropositive NMOSD treated at 6 regional hospitals and 16 tertiary referral centers until March 2013. Besides descriptive data analysis of patient and attack characteristics, generalized estimation equation (GEE) analyses were applied to compare the effectiveness of the 2 apheresis techniques. A GEE model was generated to assess predictors of outcome. Results Two hundred and seven attacks in 105 patients (87% AQP4-ab-antibody seropositive) were treated with at least 1 apheresis therapy. Neither PE nor IA was proven superior in the therapy of NMOSD attacks. CR was only achieved with early apheresis therapy. Strong predictors for CR were the use of apheresis therapy as first-line therapy (OR 12.27, 95% CI: 1.04-144.91, p = 0.047), time from onset of attack to start of therapy in days (OR 0.94, 95% CI: 0.89-0.99, p = 0.014), the presence of AQP4-abantibodies (OR 33.34, 95% CI: 1.76-631.17, p = 0.019), and monofocal attack manifestation (OR 4.71, 95% CI: 1.03-21.62, p = 0.046). Conclusion: s Our findings suggest early use of an apheresis therapy in NMOSD attacks, particularly in AQP4-ab-seropositive patients. No superiority was shown for one of the 2 apheresis techniques
Search for Prompt Neutrino Emission from Gamma-Ray Bursts with IceCube
We present constraints derived from a search of four years of IceCube data
for a prompt neutrino flux from gamma-ray bursts (GRBs). A single
low-significance neutrino, compatible with the atmospheric neutrino background,
was found in coincidence with one of the 506 observed bursts. Although GRBs
have been proposed as candidate sources for ultra-high energy cosmic rays, our
limits on the neutrino flux disfavor much of the parameter space for the latest
models. We also find that no more than of the recently observed
astrophysical neutrino flux consists of prompt emission from GRBs that are
potentially observable by existing satellites.Comment: 15 pages, 3 figure
Measurement of the Atmospheric Spectrum with IceCube
We present a measurement of the atmospheric spectrum at energies
between 0.1 TeV and 100 TeV using data from the first year of the complete
IceCube detector. Atmospheric originate mainly from the decays of kaons
produced in cosmic-ray air showers. This analysis selects 1078 fully contained
events in 332 days of livetime, then identifies those consistent with particle
showers. A likelihood analysis with improved event selection extends our
previous measurement of the conventional fluxes to higher energies. The
data constrain the conventional flux to be times a
baseline prediction from a Honda's calculation, including the knee of the
cosmic-ray spectrum. A fit to the kaon contribution () to the neutrino
flux finds a kaon component that is times the baseline
value. The fitted/measured prompt neutrino flux from charmed hadron decays
strongly depends on the assumed astrophysical flux and shape. If the
astrophysical component follows a power law, the result for the prompt flux is
times a calculated flux based on the work by Enberg, Reno
and Sarcevic.Comment: PRD accepted versio
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