105 research outputs found

    Effects of decontamination, sterilization, and preconditioning treatments on energy- dissipating properties of balsa wood

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    Decontamination, sterilization, and preconditioning effects on energy dissipating properties of balsa woo

    Automatic sample rotator for metallographic polishing

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    Simple, inexpensive device can be attached to most metallographic sample polishing tables. It provides a suitable surface finish for microscopic examination or photography of surface details of the samples

    Thermal Properties of a Simulated Lunar Material in Air and in Vacuum

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    Thermal properties of simulated lunar material in air and in vacuu

    Rapid-Rate Compression Testing of Sheet Materials at High Temperatures

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    This Report describes the test equipment that was developed and the procedures that were used to evaluate structural sheet-material compression properties at preselected constant strain rates and/or loads. Electrical self-resistance was used to achieve a rapid heating rate of 200 F/sec. Four materials were tested at maximum temperatures which ranged from 600 F for the aluminum alloy to 2000 F for the Ni-Cr-Co iron-base alloy. Tests at 0.1, 0.001, and 0.00001 in./in./sec showed that strain rate has a major effect on the measured strength, especially at the high temperatures. The tests, under conditions of constant temperature and constant compression stress, showed that creep deformation can be a critical factor even when the time involved is on the order of a few seconds or less. The theoretical and practical aspects of rapid-rate compression testing are presented, and suggestions are made regarding possible modifications of the equipment which would improve the over-all capabilities

    The Bearing Capacity of Simulated Lunar Surfaces in Vacuum

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    The static bearing capacity of a granular material consisting of dry, crushed olivine basalt was determined in air and in a 10^(-6) mm Hg vacuum by means of cylindrical probes with a range of diameters. Samples with various particle size distributions (all below 35 mesh) were used for these tests. It was found that the packing density of these granular materials was the factor which had the greatest effect on the bearing capacity. The minimum bearing capacity of a loosely packed sample with a density of 1.25 g/cm^3 was about 0.1 kg/cm^2. The maximum bearing capacity of a densely packed sample with density of 2.1 g/cm^3 was about 7 kg/cm^2. The effects of vacuum were insignificant compared with the effect of packing density. Direct shear tests indicated the cohesion in a few densely packed samples to be 1-2 X 10^4 dynes/cm^2. For the small probes used, the cohesion was estimated to contribute 85 to 95% of the observed bearing capacity for the densely packed samples, but much less for the loosely packed samples

    Relic Neutralino Densities and Detection Rates with Nonuniversal Gaugino Masses

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    We extend previous analyses on the interplay between nonuniversalities in the gaugino mass sector and the thermal relic densities of LSP neutralinos, in particular to the case of moderate to large tan beta. We introduce a set of parameters that generalizes the standard unified scenario to cover the complete allowed parameter space in the gaugino mass sector. We discuss the physical significance of the cosmologically preferred degree of degeneracy between charginos and the LSP and study the effect this degree of degeneracy has on the prospects for direct detection of relic neutralinos in the next round of dark matter detection experiments. Lastly, we compare the fine tuning required to achieve a satisfactory relic density with the case of universal gaugino masses, as in minimal supergravity, and find it to be of a similar magnitude. The sensitivity of quantifiable measures of fine-tuning on such factors as the gluino mass and top and bottom masses is also examined.Comment: Uses RevTeX; 14 pages, 16 figure

    Bearing capacity of simulated lunar surfaces in vacuum

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    Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung

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    In this study, we detail a novel approach that combines bacterial fitness fluorescent reporter strains with scRNA-seq to simultaneously acquire the host transcriptome, surface marker expression, and bacterial phenotype for each infected cell. This approach facilitates the dissection of the functional heterogeneity of M. tuberculosis-infected alveolar (AMs) and interstitial macrophages (IMs) in vivo. We identify clusters of pro-inflammatory AMs associated with stressed bacteria, in addition to three different populations of IMs with heterogeneous bacterial phenotypes. Finally, we show that the main macrophage populations in the lung are epigenetically constrained in their response to infection, while inter-species comparison reveals that most AMs subsets are conserved between mice and humans. This conceptual approach is readily transferable to other infectious disease agents with the potential for an increased understanding of the roles that different host cell populations play during the course of an infection

    Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma

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    Kallikreins play an important role in tumour microenvironment and as cancer biomarkers in different cancer entities. Previous studies suggested an upregulation of KLK10 and KLK6 in pancreatic ductal adenocarcinoma (PDAC). Therefore, we evaluated the clinicopathological role of these kallikreins and their value as biomarkers in PDAC
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