5,945 research outputs found

    Parametrically driven nonlinear Dirac equation with arbitrary nonlinearity

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    The damped and parametrically driven nonlinear Dirac equation with arbitrary nonlinearity parameter κ is analyzed, when the external force is periodic in space and given by f(x) = r cos(Kx), both numerically and in a variational approximation using five collective coordinates (time dependent shape parameters of the wave function). Our variational approximation satisfies exactly the low-order moment equations. Because of competition between the spatial period of the external force λ = 2π/K, and the soliton width ls, which is a function of the nonlinearity κ as well as the initial frequency ω0 of the solitary wave, there is a transition (at fixed ω0) from trapped to unbound behavior of the soliton, which depends on the parameters r and K of the external force and the nonlinearity parameter κ. We previously studied this phenomena when κ = 1 (2019 J. Phys. A: Math. Theor. 52 285201) where we showed that for λ ≫ ls the soliton oscillates in an effective potential, while for λ ≪ ls it moves uniformly as a free particle. In this paper we focus on the κ dependence of the transition from oscillatory to particle behavior and explicitly compare the curves of the transition regime found in the collective coordinate approximation as a function of r and K when κ = 1/2,1,2 at fixed value of the frequency ω0. Since the solitary wave gets narrower for fixed ω0 as a function of κ, we expect and indeed find that the regime where the solitary wave is trapped is extended as we increase κ.Ministerio de Economía y Competitividad of Spain FIS2017-89349-PMinisterio de Ciencia, Innovación y Universidades of Spain PGC2018-093998-B-I0

    Priming attachment security and outgroup humanization: The mediation role of intergroup emotions

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    Individuals tend to dehumanize the outgroup. In this paper, we explore whether the activation of attachment security can attenuate dehumanization. Two studies were performed. In Study 1, attachment security was primed by showing pictures that depicted relationships with attachment figures; the outgroup was the homeless and humanization was measured considering the attribution of uniquely human and non-uniquely human emotions to this group. In Study 2, the sense of interpersonal security was activated by inviting participants to relive a recent interaction that left them with a feeling of safety and warmth. Outgroup members were the Roma, and humanization was measured considering the attribution of uniquely human and human nature traits to them. In Study 2, the mediation effect of intergroup emotions was investigated. In both studies, outgroup humanization effects were highlighted. In Study 2, these effects were mediated by increased empathy toward the outgroup. Interestingly, the positive impact of security activation was not moderated by chronic attachment orientations. Findings suggest strategies that can be used to improve intergroup relations in specific contexts and in society at large

    Strategic quantitative easing: Stimulating investment to rebalance the economy

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    The Bank of England\u2019s programmes of Quantitative Easing (QE) and Funding for Lending (FLS) are failing to stimulate GDP and rebalance the economy. Both policies falsely assume that the UK\u2019s risk-averse capital markets, corporate sector and constrained banking system can be nudged into supporting the productive economy. We propose a new approach: one that channels investment directly into new housing, infrastructure and SME lending, boosting productivity and exports. QE must become less scattergun and more strategic, with reformed governance structures to match

    Information geometry of Gaussian channels

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    We define a local Riemannian metric tensor in the manifold of Gaussian channels and the distance that it induces. We adopt an information-geometric approach and define a metric derived from the Bures-Fisher metric for quantum states. The resulting metric inherits several desirable properties from the Bures-Fisher metric and is operationally motivated from distinguishability considerations: It serves as an upper bound to the attainable quantum Fisher information for the channel parameters using Gaussian states, under generic constraints on the physically available resources. Our approach naturally includes the use of entangled Gaussian probe states. We prove that the metric enjoys some desirable properties like stability and covariance. As a byproduct, we also obtain some general results in Gaussian channel estimation that are the continuous-variable analogs of previously known results in finite dimensions. We prove that optimal probe states are always pure and bounded in the number of ancillary modes, even in the presence of constraints on the reduced state input in the channel. This has experimental and computational implications: It limits the complexity of optimal experimental setups for channel estimation and reduces the computational requirements for the evaluation of the metric: Indeed, we construct a converging algorithm for its computation. We provide explicit formulae for computing the multiparametric quantum Fisher information for dissipative channels probed with arbitrary Gaussian states, and provide the optimal observables for the estimation of the channel parameters (e.g. bath couplings, squeezing, and temperature).Comment: 19 pages, 4 figure

    Information capacity in the weak-signal approximation

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    We derive an approximate expression for mutual information in a broad class of discrete-time stationary channels with continuous input, under the constraint of vanishing input amplitude or power. The approximation describes the input by its covariance matrix, while the channel properties are described by the Fisher information matrix. This separation of input and channel properties allows us to analyze the optimality conditions in a convenient way. We show that input correlations in memoryless channels do not affect channel capacity since their effect decreases fast with vanishing input amplitude or power. On the other hand, for channels with memory, properly matching the input covariances to the dependence structure of the noise may lead to almost noiseless information transfer, even for intermediate values of the noise correlations. Since many model systems described in mathematical neuroscience and biophysics operate in the high noise regime and weak-signal conditions, we believe, that the described results are of potential interest also to researchers in these areas.Comment: 11 pages, 4 figures; accepted for publication in Physical Review

    A single-cell analysis of breast cancer cell lines to study tumour heterogeneity and drug response

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    Cancer cells within a tumour have heterogeneous phenotypes and exhibit dynamic plasticity. How to evaluate such heterogeneity and its impact on outcome and drug response is still unclear. Here, we transcriptionally profile 35,276 individual cells from 32 breast cancer cell lines to yield a single cell atlas. We find high degree of heterogeneity in the expression of biomarkers. We then train a deconvolution algorithm on the atlas to determine cell line composition from bulk gene expression profiles of tumour biopsies, thus enabling cell line-based patient stratification. Finally, we link results from large-scale in vitro drug screening in cell lines to the single cell data to computationally predict drug responses starting from single-cell profiles. We find that transcriptional heterogeneity enables cells with differential drug sensitivity to co-exist in the same population. Our work provides a framework to determine tumour heterogeneity in terms of cell line composition and drug response

    Melhoria da qualidade e produtividade de leite na Região Serrana do Rio de Janeiro

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    bitstream/item/81956/1/Melhoria-da-qualidade.pdfTrabalhos apresentados ao Rio Leite Serrano, Macuco, 2004

    Analytical Approximations of Critical Clearing Time for Parametric Analysis of Power System Transient Stability

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    An analytic approximation for the critical clearing time (CCT) metric is derived from direct methods for power system stability. The formula has been designed to incorporate as many features of transient stability analysis as possible such as different fault locations and different post-fault network states. The purpose of this metric is to analyse trends in stability (in terms of CCT) of power systems under the variation of a system parameter. The performance of this metric to measure stability trends is demonstrated on an aggregated power network, the so-called two machine infinite bus network, by varying load parameters in the full bus admittance matrix using numerical continuation. The metric is compared to two other expressions for the CCT which incorporate additional non-linearities present in the model

    Survey of Intestinal Parasites Including Associated Risk Factors Among Food Vendors and Slaughterhouse Workers in Metro Manila, Philippines

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    Infections by intestinal parasites are considered as one of the major health concerns in developing countries afflicting different groups of people including food handlers and food vendors and are linked to poor personal hygiene and sanitation. This raises public health issues as food vendors and handlers may potentially become agents for the fecal-oral transmission of intestinal parasitic infections to consumers. This study focused on determining the prevalence of intestinal parasites among slaughter house workers and food vendors and examined their personal and food hygiene practices. A small-scale survey was conducted and selected a total of 91 slaughter house workers and food vendors from different areas in Metro Manila. Microscopic examination ofthe fecal samples collected was done following standard procedures by the World Health Organization (WHO) thru direct smear, formalin-ethyl acetate sedimentation and staining methods. Participants were also interviewed on their food and personal hygiene practices using a questionnaire. The overall prevalence of parasitic infection was 90% with helminthic predominating protozoan infections. Eight (8) different intestinal parasites were identified: Entamoeba histolytica/Entamoeba dispar (15.6%), Balantidium coli (8.4%), Giardia lamblia (4.2%), Ascaris lumbricoides (30%), Trichuris trichiura (14.9%), Ancyclostoma duodenale/ Necator americanus (2.3%). Taenia spp. (2.4%), and Enterobius vermicularis (2.9%). Other amoeba-like protozoans (19.2%) were also observed suggestive of exposure to fecal materials. Based on the results obtained, there is high levels of parasitic infections among slaughter house workers and food vendors. Raising awareness on proper food handling, improved personal hygiene and sanitation is needed to prevent further transmission of parasites to the public. Keywords: Food handlers, Food safety, Intestinal parasites, Neglected Tropical Diseases, Public Health
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