4,751 research outputs found

    Levels of generalization in the objectification of the recursion step

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    In this study, we focus on the students’ objectification of the recursion step, intended as a process of generalization in the sense of Radford (2001). Building on Radford’s model, we elaborate levels of generalization of the recursion step and use them to analyze the processes activated by secondary school students during collaborative activities with geometric recursive sequences. The analysis allows us to identify different levels reached by the students in grasping the recursion step and their transitions between these levels

    Targeting oxidant-dependent mechanisms for the treatment of COPD and its comorbidities

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    Chronic obstructive pulmonary disease (COPD) is an incurable global health burden and is characterised by progressive airflow limitation and loss of lung function. In addition to the pulmonary impact of the disease, COPD patients often develop comorbid diseases such as cardiovascular disease, skeletal muscle wasting, lung cancer and osteoporosis. One key feature of COPD, yet often underappreciated, is the contribution of oxidative stress in the onset and development of the disease. Patients experience an increased burden of oxidative stress due to the combined effects of excess reactive oxygen species (ROS) and nitrogen species (RNS) generation, antioxidant depletion and reduced antioxidant enzyme activity. Currently, there is a lack of effective treatments for COPD, and an even greater lack of research regarding interventions that treat both COPD and its comorbidities. Due to the involvement of oxidative stress in the pathogenesis of COPD and many of its comorbidities, a unique therapeutic opportunity arises where the treatment of a multitude of diseases may be possible with only one therapeutic target. In this review, oxidative stress and the roles of ROS/RNS in the context of COPD and comorbid cardiovascular disease, skeletal muscle wasting, lung cancer, and osteoporosis are discussed and the potential for therapeutic benefit of anti-oxidative treatment in these conditions is outlined. Because of the unique interplay between oxidative stress and these diseases, oxidative stress represents a novel target for the treatment of COPD and its comorbidities

    Talking about Good and Bad Learners: Linguistic Dimension of Implicit Theories of Intelligence

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    Abstract Introduction. Implicit theories of intelligence are lay beliefs about whether intelligence i

    Cokebildung und Entcoking während der Methanbildung und des Methanzerfalls auf Ni-Cu-Trägerkatalysatoren

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    The effect of the composition of silica supported Ni-Cu alloy catalysts on the process of coking and decoking during methane decomposition and during methanation was considered. The kinetics of methanation was studied and compared to those of carbon deposition and of strong adsorption of hydrogen. Initiation of the formation of filamentous carbon formation on mono-metallic surfaces may take place if the ratio of the partial pressures, pCO/pH2, is larger than 2 (T 673 K). Once the process starts, the chemical potential of the gas phase may be reduced to lower values without interruption of filament growth. Besides, it was concluded that the methanation reaction includes two steps: the dissociative adsorption of CO and the hydrogenation of the adsorbed species. It was possible to establish the mechanism through which Cu affects the activity of Ni. The effect of the composition of the alloy catalysts on the methane formation and on the simultaneous carbon deposition indicates that those reactions belong to group I and to group II, respectively, following Ponec's classification. It was possible to find the optimal Cu concentration that maximises methanation and minimises carbon deposition. The kinetics of methane decomposition was also considered and is well described by adapting a model developed by other authors for Fe catalysts

    Shrinking Point Bifurcations of Resonance Tongues for Piecewise-Smooth, Continuous Maps

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    Resonance tongues are mode-locking regions of parameter space in which stable periodic solutions occur; they commonly occur, for example, near Neimark-Sacker bifurcations. For piecewise-smooth, continuous maps these tongues typically have a distinctive lens-chain (or sausage) shape in two-parameter bifurcation diagrams. We give a symbolic description of a class of "rotational" periodic solutions that display lens-chain structures for a general NN-dimensional map. We then unfold the codimension-two, shrinking point bifurcation, where the tongues have zero width. A number of codimension-one bifurcation curves emanate from shrinking points and we determine those that form tongue boundaries.Comment: 27 pages, 6 figure

    Aproximació a l'antropologia i la cultura popular a Torrent. Projecte de recerca antropològica i museu etnogràfic

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    Projecte de recerca i museu etnogrĂ fic realitzat als Instituts de Batxillerat de Torrent "Serra Perenxisa" i "Tirant lo Blanc", en el curs 1991-1992

    Anatomy and physiology of cisternostomy

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    Cisternostomy is defined as opening the basal cisterns to atmospheric pressure. This technique helps to reduce the intracranial pressure in severe head trauma as well as other conditions when the so-called sudden "brain swelling" troubles the surgeon. We elaborated the surgical anatomy of this procedure as well as the proposed physiology of how cisternostomy works. This novel technique may change the current trends in neurosurgery

    Application of an autonomous robot for the collection of nearshore topographic and hydrodynamic measurements

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    Beach topographic and hydrodynamic measurements are essential for coastal geology and engineering studies as well as sustainable coastal management. Standard approaches involve either time-consuming manual data acquisition usually with limited coverage or remote sensing techniques which are usually characterized by low resolution or increased costs. The present contribution reports the results from the application of the autonomous robot RTS-Hanna with a calibrated sensor setup including 3D laser range scanners, a camera, a Differential GPS and an inertial measurement unit which significantly facilitates field data collection. RTS-Hanna was tested at the Wadden Sea Barrier Island Langeoog, Northern Germany, for two days and was proven capable of autonomously collecting topographic scans. 175 GB of dense topographic and water surface elevation data were collected, including RBG images, while RTS-Hanna covered a total of 21 km of coastline in approximately 3 hours. Scans of the surf/swash zone allowed continuous measurements of topographic changes at the beachface, wave propagation velocities and wave breaking heights
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