5 research outputs found

    Kids geosciences labs: the experience of “Sabato al Museo” 2016

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    During the events “Sabato al Museo” (7th and 21th May 2016) and the European Night at the Museums (21th May 2016), organized by the Polo museale Sapienza (https://web.uniroma1.it/polomuseale/), the Italian Geological Society (SGI - http://www.socgeol.it/) designed and realized six laboratories for children. These were carried out at “Sapienza University of Rome” inside the MUST (University Museum of Earth Science) and the Museum of Anthropology. The main goal of these labs was to mediate the research activities performed by the Sapienza University in different fields of geosciences to an audience of children (from six to twelve years old). The laboratories were holded by selected experts in teaching and disseminating for children. The activities were organized in two phases. In the first phase (about 15 minutes), the operators introduced the audience in the topic of the laboratory by means of multimedia material, involving children with questions and discussions. In the second phase (about thirty minutes), the children carried out experimental activities using the proper scientific methodology. The SGI organized and realized the following laboratories: “Dinosaurs… even in Italy!” (in collaboration with MUSE – Science Museum of Trento); “Footprints”; “Microworlds” (a micropalentological laboratory); “Prey and predators” (in collaboration with PaleoFactory Lab – Sapienza University of Rome); “Discovering our history: apes, fossils and man” and “Ancient weapons”. About 800 children attended these laboratories. The feedback of the audience proved to be very positive, as testified by ex post questionnaires; they had indeed the opportunity to explore topics that commonly capture their imagination. We are deeply convinced that these activities can greatly contribute to expanding the cultural background of the younger generations, in particular the geosciences that unfortunately are still too neglected

    Direct Nucleophilic Difluoromethylation of Aromatic Isoxazoles Activated by Electron-Withdrawing Groups Using (Difluoromethyl)trimethylsilane

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    Direct Nucleophilic Difluoromethylation of Aromatic Isoxazoles Activated by Electron-Withdrawing Groups Using (Difluoromethyl)trimethylsilane

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    Appropriateness of antiplatelet therapy for primary and secondary cardio- and cerebrovascular prevention in acutely hospitalized older people

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    Aims: Antiplatelet therapy is recommended for the secondary prevention of cardio- and cerebrovascular disease, but for primary prevention it is advised only in patients at very high risk. With this background, this study aims to assess the appropriateness of antiplatelet therapy in acutely hospitalized older people according to their risk profile. Methods: Data were obtained from the REPOSI register held in Italian and Spanish internal medicine and geriatric wards in 2012 and 2014. Hospitalized patients aged 6565 assessable at discharge were selected. Appropriateness of the antiplatelet therapy was evaluated according to their primary or secondary cardiovascular prevention profiles. Results: Of 2535 enrolled patients, 2199 were assessable at discharge. Overall 959 (43.6%, 95% CI 41.5\u201345.7) were prescribed an antiplatelet drug, aspirin being the most frequently chosen. Among patients prescribed for primary prevention, just over half were inappropriately prescribed (52.1%), being mainly overprescribed (155/209 patients, 74.2%). On the other hand, there was also a high rate of inappropriate underprescription in the context of secondary prevention (222/726 patients, 30.6%, 95% CI 27.3\u201334.0%). Conclusions: This study carried out in acutely hospitalized older people shows a high degree of inappropriate prescription among patients prescribed with antiplatelets for primary prevention, mainly due to overprescription. Further, a large proportion of patients who had had overt cardio- or cerebrovascular disease were underprescribed, in spite of the established benefits of antiplatelet drugs in the context of secondary prevention
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