Particle Dispersion on Rapidly Folding Random Hetero-Polymers

We investigate the dynamics of a particle moving randomly along a disordered hetero-polymer subjected to rapid conformational changes which induce superdiffusive motion in chemical coordinates. We study the antagonistic interplay between the enhanced diffusion and the quenched disorder. The dispersion speed exhibits universal behavior independent of the folding statistics. On the other hand it is strongly affected by the structure of the disordered potential. The results may serve as a reference point for a number of translocation phenomena observed in biological cells, such as protein dynamics on DNA strands.Comment: 4 pages, 4 figure

Potts models in the continuum. Uniqueness and exponential decay in the restricted ensembles

In this paper we study a continuum version of the Potts model. Particles are points in R^d, with a spin which may take S possible values, S being at least 3. Particles with different spins repel each other via a Kac pair potential. In mean field, for any inverse temperature there is a value of the chemical potential at which S+1 distinct phases coexist. For each mean field pure phase, we introduce a restricted ensemble which is defined so that the empirical particles densities are close to the mean field values. Then, in the spirit of the Dobrushin Shlosman theory, we get uniqueness and exponential decay of correlations when the range of the interaction is large enough. In a second paper, we will use such a result to implement the Pirogov-Sinai scheme proving coexistence of S+1 extremal DLR measures.Comment: 72 pages, 1 figur

Inflation from D3-brane motion in the background of D5-branes

We study inflation arising from the motion of a BPS D3-brane in the background of a stack of k parallel D5-branes. There are two scalar fields in this set up-- (i) the radion field R, a real scalar field, and (ii) a complex tachyonic scalar field chi living on the world volume of the open string stretched between the D3 and D5 branes. We find that inflation is realized by the potential of the radion field, which satisfies observational constraints coming from the Cosmic Microwave Background. After the radion becomes of order the string length scale l_s, the dynamics is governed by the potential of the complex scalar field. Since this field has a standard kinematic term, reheating can be successfully realized by the mechanism of tachyonic preheating with spontaneous symmetry breaking.Comment: 10 pages, 4 figures. Minor clarifications and references added. Version to appear in Phys. Rev.

Time-dependent appearance of myofibroblasts in granulation tissue of human skin wounds

Human skin wounds (66) inflicted between 20 h and 7 months prior to biopsy were studied. In order to identify the type of cellular differentiation of the fibroblastic cells in the granulation tissue, alpha-smooth muscle actin and desmin were immunohistochemically localized. The value of any presumed time-dependent appearance and/or disappearance of positively stained cells was tested for the estimation of wound age. In skin specimens with a wound age less than 5 days (n =15) no typical granulation tissue had developed and no alpha-actin-positive myofibroblasts could be detected. The first appearance of positively reacting myofibroblasts was noted in a 5-day-old wound. In 57% of the lesions with a wound age between 5 and 31 days (25 out of 44 cases) typical granulation tissue formation was present and myofibroblasts with positive reaction for alpha-smooth muscle actin could be identified. Numerous positively reacting cells could generally be found in wounds aged between 16 and 31 days, but also in wounds less than 16 days old. In 29% of the cases with a wound age of more than 31 days (2 out of 7 cases) alpha-sma-positive myofibroblasts also occured. Fibroblastic cells positive for desmin could not be seen at all in our series. Our results demonstrate the appearance of alpha-sma-positive myofibroblasts with the initial formation of typical granulation tissue in human skin lesions as early as approximately 5 days after wounding. In contrast to recent experimental results these cells remained detectable in wounds aged more than 2 months in some cases. The immunohistochemical detection of actin-positive cells, therefore, demonstrates whether an unknown skin wound is aged approximately 5 days or more. Even though a time-dependent decrease of myofibroblasts in human granulation tissue after 31 days in human wounds seems probable, the extended presence (up to about 2 months) of these cells allows no further exact age determination of older wounds

New Cataclysmic Variables and other Exotic Binaries in the Globular Cluster 47 Tucanae

We present 22 new (+3 confirmed) cataclysmic variables (CVs) in the non core-collapsed globular cluster 47 Tucanae (47 Tuc). The total number of CVs in the cluster is now 43, the largest sample in any globular cluster so far. For the identifications we used near-ultraviolet (NUV) and optical images from the Hubble Space Telescope, in combination with X-ray results from the Chandra X-ray Observatory. This allowed us to build the deepest NUV CV luminosity function of the cluster to date. We found that the CVs in 47 Tuc are more concentrated towards the cluster center than the main sequence turnoff stars. We compared our results to the CV populations of the core-collapsed globular clusters NGC 6397 and NGC 6752. We found that 47 Tuc has fewer bright CVs per unit mass than those two other clusters. That suggests that dynamical interactions in core-collapsed clusters play a major role creating new CVs. In 47 Tuc, the CV population is probably dominated by primordial and old dynamically formed systems. We estimated that the CVs in 47 Tuc have total masses of approx. 1.4 M_sun. We also found that the X-ray luminosity function of the CVs in the three clusters is bimodal. Additionally, we discuss a possible double degenerate system and an intriguing/unclassified object. Finally, we present four systems that could be millisecond pulsar companions given their X-ray and NUV/optical colors. For one of them we present very strong evidence for being an ablated companion. The other three could be CO- or He-WDs.Comment: Published on MNRAS. 31 Pages, 23 Figures, 5 Tables. Minor changes with respect to previous arXiv versio

Long-term observations of the pulsars in 47 Tucanae. I. A study of four elusive binary systems

For the past couple of decades, the Parkes radio telescope has been regularly observing the millisecond pulsars in 47 Tucanae (47 Tuc). This long-term timing program was designed to address a wide range of scientific issues related to these pulsars and the globular cluster where they are located. In this paper, the first of a series, we address one of these objectives: the characterization of four previously known binary pulsars for which no precise orbital parameters were known, namely 47 Tuc P, V, W and X (pulsars 47 Tuc R and Y are discussed elsewhere). We determined the previously unknown orbital parameters of 47 Tuc V and X and greatly improved those of 47 Tuc P and W. For pulsars W and X we obtained, for the first time, full coherent timing solutions across the whole data span, which allowed a much more detailed characterization of these systems. 47 Tuc W, a well-known tight eclipsing binary pulsar, exhibits a large orbital period variability, as expected for a system of its class. 47 Tuc X turns out to be in a wide, extremely circular, 10.9-day long binary orbit and its position is ~3.8 arcmin away from the cluster center, more than three times the distance of any other pulsar in 47 Tuc. These characteristics make 47 Tuc X a very different object with respect to the other pulsars of the cluster.Comment: Accepted for publication by MNRAS, 18 pages, 11 figure

Crescimento diamétrico de maçaranduba (Manilkara Huberi Chevalier) após a colheita da madeira.

Conhecer o crescimento das espécies de um povoamento florestal, principalmente daquelas de interesse econômico, é de fundamental importância para o manejo florestal. Nesse sentido, avaliou-se o processo dinâmico do crescimento diamétrico da população de maçaranduba (Manilkara huberi Chevalier), no período de 1981-1997, em uma área de 64 hectares localizada na Floresta Nacional do Tapajós, área experimental sob responsabilidade da Embrapa Amazônia Oriental. Os dados foram coletados em 36 parcelas permanentes de 0,25ha (50mx50m), divididas em 25 subparcelas de 10mx10m, onde foram medidas e identificadas todas as árvores com DAP (diâmetro a 1,30 do solo) e 5cm. A espécie teve, no período de 1981-1997, crescimento médio em diâmetro de 0,39cm/ano. As árvores cujas copas receberam iluminação total cresceram 0,67cm/ano, superior àquelas que receberam iluminação parcial (0,58cm/ano) e às que estavam totalmente sombreadas (0,26cm/ano). Portanto, as árvores necessitam de iluminação para acelerar seu crescimento. As árvores sem cipós na copa cresceram em média 0,60cm/ano, enquanto que aquelas com cipós cresceram 0,45cm/ano, indicando que a infestação de cipós nas árvores afeta o seu crescimento.Disponível também on-line

Mean first-passage time of surface-mediated diffusion in spherical domains

We present an exact calculation of the mean first-passage time to a target on the surface of a 2D or 3D spherical domain, for a molecule alternating phases of surface diffusion on the domain boundary and phases of bulk diffusion. The presented approach is based on an integral equation which can be solved analytically. Numerically validated approximation schemes, which provide more tractable expressions of the mean first-passage time are also proposed. In the framework of this minimal model of surface-mediated reactions, we show analytically that the mean reaction time can be minimized as a function of the desorption rate from the surface.Comment: to appear in J. Stat. Phy