3,780 research outputs found

    A Metagenomic Hybrid Classifier for Paediatric Inflammatory Bowel Disease

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    Bosonic Fractionalisation Transitions

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    At finite density, charge in holographic systems can be sourced either by explicit matter sources in the bulk or by bulk horizons. In this paper we find bosonic solutions of both types, breaking a global U(1) symmetry in the former case and leaving it unbroken in the latter. Using a minimal bottom-up model we exhibit phase transitions between the two cases, under the influence of a relevant operator in the dual field theory. We also embed solutions and transitions of this type in M-theory, where, holding the theory at constant chemical potential, the cohesive phase is connected to a neutral phase of Schr\"odinger type via a z=2 QCP.Comment: references added. minor changes. version published in JHE

    A soliton menagerie in AdS

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    We explore the behaviour of charged scalar solitons in asymptotically global AdS4 spacetimes. This is motivated in part by attempting to identify under what circumstances such objects can become large relative to the AdS length scale. We demonstrate that such solitons generically do get large and in fact in the planar limit smoothly connect up with the zero temperature limit of planar scalar hair black holes. In particular, for given Lagrangian parameters we encounter multiple branches of solitons: some which are perturbatively connected to the AdS vacuum and surprisingly, some which are not. We explore the phase space of solutions by tuning the charge of the scalar field and changing scalar boundary conditions at AdS asymptopia, finding intriguing critical behaviour as a function of these parameters. We demonstrate these features not only for phenomenologically motivated gravitational Abelian-Higgs models, but also for models that can be consistently embedded into eleven dimensional supergravity.Comment: 62 pages, 21 figures. v2: added refs and comments and updated appendice

    Potential use of rhizobium for vegetable crops growth promotion

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    The system of vegetable crops production required large amounts of mineral fertilizers. One of the possible alternatives to assure the economic and environmental sustainability of this production system would be the use of promoting growth plant rhizobacteria (PGPR). However, care is needed to select a microorganism to be used in crops that are usually consumed raw, so human health is not at risk. It was important to search for PGPR, as rhizobium, that already were broadly used as inoculants for leguminous plants for several decades, without risks to human health. PGPR can promote growth and development of plants through direct and indirect mechanisms, by production and secretion of chemical substances in the rhizosphere. The direct mechanisms were involved with the uptake of nutrients by the plants (nitrogen, phosphorus and essential minerals) through phosphate solubilization, production of siderophores and growth regulators. The indirect mechanisms were involved with the decrease of inhibitory effects from various pathogenic agents related with biological pest control, thereby favoring plant growth. Nevertheless, due to its ability to promote beneficial effects to plants, effective bacterial colonization was extremely important. Some bacteria that colonized the rhizoplane may penetrate the plant roots and some strains may move to the aerial part, with decreased bacterial density, compared with colonizing populations in the rhizosphere or roots. It can be concluded that Rhizobia promotes plant growth using different mechanisms as biological nitrogen fixation and production of different plant growth regulators (e.g. auxins). Therefore, new studies with Rhizobia characterization and observation about its different mechanisms of promoting plant growth should be performed. Such information would be useful for the identification of plants with potential to increase agricultural production due to the benefits of using plant growth promoter’s rhizobia

    Trends in all-cause mortality during the scale-up of an antiretroviral therapy programme: a cross-sectional study in Lusaka, Zambia.

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    OBJECTIVE: To follow the trends in all-cause mortality in Lusaka, Zambia, during the scale-up of a national programme of antiretroviral therapy (ART). METHODS: Between November 2004 and September 2011, we conducted 12 survey rounds as part of a cross-sectional study in Lusaka, with independent sampling in each round. In each survey, we asked the heads of 3600 households to state the number of deaths in their households in the previous 12 months and the number of orphans aged less than 16 years in their households and investigated the heads' knowledge, attitudes and practices related to human immunodeficiency virus (HIV). FINDINGS: The number of deaths we recorded - per 100 person-years - in each survey ranged from 0.92 (95% confidence interval, CI: 0.78-1.09) in September 2011, to 1.94 (95% CI: 1.60-2.35) in March 2007. We found that mortality decreased only modestly each year (mortality rate ratio: 0.98; 95% CI: 0.95-1.00; P = 0.093). The proportion of households with orphans under the age of 16 years decreased from 17% in 2004 to 7% in 2011. The proportions of respondents who had ever been tested for HIV, had a comprehensive knowledge of HIV, knew where to obtain free ART and reported that a non-pregnant household member was receiving ART gradually increased. CONCLUSION: The expansion of ART services in Lusaka was not associated with a reduction in all-cause mortality. Coverage, patient adherence and retention may all have to be increased if ART is to have a robust and lasting impact at population level in Lusaka

    Rhizobial inoculation, alone or coinoculated with Azospirillum brasilense, promotes growth of wetland rice

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    Rhizobia and associative bacteria promote growth in rice plants (Oryza sativa L.) through a series of mechanisms, but most studies on inoculation have been performed based on inoculation with these bacteria in a separate or singular manner. The objective of this study was to assess the efficiency of single/isolated inoculation and inoculation combined with symbiotic rhizobia from forage legume and with Azospirillum brasilense on promoting growth and the root colonization process in wetland rice. Two rhizobia among four isolates from a greenhouse and a laboratory experiment were selected that efficiently promoted seed germination and rice plant growth in a sterilized substrate and in soil. The two most efficient isolates (UFRGS Vp16 and UFRGS Lc348) were inoculated alone or in combination with a commercial product containing A. brasilense in two field experiments using two wetland rice cultivars over two growing seasons. In the field experiments, these isolates coinoculated with A. brasilense promoted larger increases in the agronomic variables of wetland rice compared to the control without inoculation. Confocal laser microscopy confirmed the presence of inoculated bacteria tagged with gfp (UFRGS Vp16, UFRGS Lc348, and A. brasilense) colonizing the root surface of the rice seedlings, mainly in the root hairs and lateral roots

    Premature adult mortality in urban Zambia: a repeated population-based cross-sectional study.

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    OBJECTIVES: To measure the sex-specific and community-specific mortality rates for adults in Lusaka, Zambia, and to identify potential individual-level, household-level and community-level correlates of premature mortality. We conducted 12 survey rounds of a population-based cross-sectional study between 2004 and 2011, and collected data via a structured interview with a household head. SETTING: Households in Lusaka District, Zambia, 2004-2011. PARTICIPANTS: 43,064 household heads (88% female) who enumerated 123,807 adult household members aged between 15 and 60 years. PRIMARY OUTCOME: Premature adult mortality. RESULTS: The overall mortality rate was 16.2/1000 person-years for men and 12.3/1000 person-years for women. The conditional probability of dying between age 15 and 60 (45q15) was 0.626 for men and 0.537 for women. The top three causes of death for men and women were infectious in origin (ie, tuberculosis, HIV and malaria). We observed an over twofold variation of mortality rates between communities. The mortality rate was 1.98 times higher (95% CI 1.57 to 2.51) in households where a family member required nursing care, 1.44 times higher (95% CI 1.22 to 1.71) during the cool dry season, and 1.28 times higher (95% CI 1.06 to 1.54) in communities with low-cost housing. CONCLUSIONS: To meet Zambia's development goals, further investigation is needed into the factors associated with adult mortality. Mortality can potentially be reduced through focus on high-need households and communities, and improved infectious disease prevention and treatment services
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