6 research outputs found
Diagnosis of Cystic Echinococcosis, Central Peruvian Highlands
High prevalence was confirmed by ultrasonography, radiography, and 2 serologic tests, although usefulness of serologic testing in the field was limited
HTLV-1 infection in solid organ transplant donors and recipients in Spain
HTLV-1 infection is a neglected disease, despite infecting 10-15 million people worldwide and severe illnesses develop in 10% of carriers lifelong. Acknowledging a greater risk for developing HTLV-1 associated illnesses due to immunosuppression, screening is being widely considered in the transplantation setting. Herein, we report the experience with universal HTLV testing of donors and recipients of solid organ transplants in a survey conducted in Spain. All hospitals belonging to the Spanish HTLV network were invited to participate in the study. Briefly, HTLV antibody screening was performed retrospectively in all specimens collected from solid organ donors and recipients attended since the year 2008. A total of 5751 individuals were tested for HTLV antibodies at 8 sites. Donors represented 2312 (42.2%), of whom 17 (0.3%) were living kidney donors. The remaining 3439 (59.8%) were recipients. Spaniards represented nearly 80%. Overall, 9 individuals (0.16%) were initially reactive for HTLV antibodies. Six were donors and 3 were recipients. Using confirmatory tests, HTLV-1 could be confirmed in only two donors, one Spaniard and another from Colombia. Both kidneys of the Spaniard were inadvertently transplanted. Subacute myelopathy developed within 1 year in one recipient. The second recipient seroconverted for HTLV-1 but the kidney had to be removed soon due to rejection. Immunosuppression was stopped and 3 years later the patient remains in dialysis but otherwise asymptomatic. The rate of HTLV-1 is low but not negligible in donors/recipients of solid organ transplants in Spain. Universal HTLV screening should be recommended in all donor and recipients of solid organ transplantation in Spain. Evidence is overwhelming for very high virus transmission and increased risk along with the rapid development of subacute myelopathy
Herramientas de aprendizaje para estudiantes de secundaria en el campo de la Genética
Se ha diseñado una actividad: la caracterizaciĂłn molecular de la mutaciĂłn de un gen que modifica el color de los ojos en Drosophila melanogaster, partiendo de un carĂĄcter morfolĂłgico, el color de los ojos, se obtendrĂĄ la secuencia del gen responsable y su localizaciĂłn en el genoma de la especie. Se pretende desarrollar una actividad prĂĄctica que permita a los alumnos de segundo ciclo de la ESO comprender la genĂ©tica y la genĂłmica y cĂłmo estos conocimientos se pueden aplicar a distintas ĂĄreas: salud, biotecnologĂa o impacto ambiental
AsociaciĂłn entre catastrofismo y depresiĂłn en poblaciĂłn deportista con SĂndrome de Dolor Miofascial en los mĂșsculos gastrocnemios
Nuestra hipĂłtesis constĂł de la existencia de una correlaciĂłn de moderadas o fuertes entre el factor
catastrofismo y puntuaciones de depresiĂłn, en poblaciĂłn deportistas que presentaba SDM en mĂșsculos
gastrocnemios
Open Lab
Depto. de GenĂ©tica, FisiologĂa y MicrobiologĂaFac. de Ciencias BiolĂłgicasFALSEsubmitte