380 research outputs found
Political Participation of Ethnic Associations: Exploring the Importance of Organisational Level Differences in Resources, Motivation and Recruitment Networks
In this paper, we apply the Civic Voluntarism Model (CVM) proposed by Verba, Schlozman and Brady on the organisational level. Simultaneously contributing to the research on the political integration of ethnic minorities, we examine resources, motivation and recruitment networks of ethnic associations, and probe the extent to which these mechanisms influence collectively organised political participation. We use data based on face to face interviews with representatives of 106 organisations of four different immigrant groups in Stockholm. Our results indicate that participation rates of ethnic associations vary with size, access to information technology, level of internal democracy, overall aspiration to influence society, and contacts with political elites. Noteworthy, however, our analyses suggest that membersâ proficiency in the Swedish language is not important in this respect. Conceptually and methodologically the study demonstrates how the CVM can be fruitfully applied when analysing differences in the political activity of voluntary associations.Ethnic minorities; Political integration; Ethnic associations; Political participation; Civic Voluntarism Model; Voluntary associations
Sharp failure rates for the bootstrap particle filter in high dimensions
We prove that the maximum of the sample importance weights in a
high-dimensional Gaussian particle filter converges to unity unless the
ensemble size grows exponentially in the system dimension. Our work is
motivated by and parallels the derivations of Bengtsson, Bickel and Li (2007);
however, we weaken their assumptions on the eigenvalues of the covariance
matrix of the prior distribution and establish rigorously their strong
conjecture on when weight collapse occurs. Specifically, we remove the
assumption that the nonzero eigenvalues are bounded away from zero, which,
although the dimension of the involved vectors grow to infinity, essentially
permits the effective system dimension to be bounded. Moreover, with some
restrictions on the rate of growth of the maximum eigenvalue, we relax their
assumption that the eigenvalues are bounded from above, allowing the system to
be dominated by a single mode.Comment: Published in at http://dx.doi.org/10.1214/074921708000000228 the IMS
Collections (http://www.imstat.org/publications/imscollections.htm) by the
Institute of Mathematical Statistics (http://www.imstat.org
Low-Complexity OFDM Spectral Precoding
This paper proposes a new large-scale mask-compliant spectral precoder
(LS-MSP) for orthogonal frequency division multiplexing systems. In this paper,
we first consider a previously proposed mask-compliant spectral precoding
scheme that utilizes a generic convex optimization solver which suffers from
high computational complexity, notably in large-scale systems. To mitigate the
complexity of computing the LS-MSP, we propose a divide-and-conquer approach
that breaks the original problem into smaller rank 1 quadratic-constraint
problems and each small problem yields closed-form solution. Based on these
solutions, we develop three specialized first-order low-complexity algorithms,
based on 1) projection on convex sets and 2) the alternating direction method
of multipliers. We also develop an algorithm that capitalizes on the
closed-form solutions for the rank 1 quadratic constraints, which is referred
to as 3) semi-analytical spectral precoding. Numerical results show that the
proposed LS-MSP techniques outperform previously proposed techniques in terms
of the computational burden while complying with the spectrum mask. The results
also indicate that 3) typically needs 3 iterations to achieve similar results
as 1) and 2) at the expense of a slightly increased computational complexity.Comment: Accepted in IEEE International Workshop on Signal Processing Advances
in Wireless Communications (SPAWC), 201
Curse-of-dimensionality revisited: Collapse of the particle filter in very large scale systems
It has been widely realized that Monte Carlo methods (approximation via a
sample ensemble) may fail in large scale systems. This work offers some
theoretical insight into this phenomenon in the context of the particle filter.
We demonstrate that the maximum of the weights associated with the sample
ensemble converges to one as both the sample size and the system dimension
tends to infinity. Specifically, under fairly weak assumptions, if the ensemble
size grows sub-exponentially in the cube root of the system dimension, the
convergence holds for a single update step in state-space models with
independent and identically distributed kernels. Further, in an important
special case, more refined arguments show (and our simulations suggest) that
the convergence to unity occurs unless the ensemble grows super-exponentially
in the system dimension. The weight singularity is also established in models
with more general multivariate likelihoods, e.g. Gaussian and Cauchy. Although
presented in the context of atmospheric data assimilation for numerical weather
prediction, our results are generally valid for high-dimensional particle
filters.Comment: Published in at http://dx.doi.org/10.1214/193940307000000518 the IMS
Collections (http://www.imstat.org/publications/imscollections.htm) by the
Institute of Mathematical Statistics (http://www.imstat.org
Understanding contextualised rational action - author's response
Understanding contextualised rational action - author's respons
Decreased levels of stem cell factor in subjects with incident coronary events.
It has been proposed that vascular progenitor cells play an important role in vascular repair, but their possible clinical importance in cardiovascular disease has not been fully characterized. Vascular endothelial growth factor A, placental growth factor and stem cell factor (SCF) are three growth factors that are important in recruiting vascular progenitor cells. In this study, we investigated the association between the plasma levels of these growth factors and incident coronary events (CEs)
Microbial and human transcriptome in vaginal fluid at midgestation: Association with spontaneous preterm delivery
Background Intrauterine infection and inflammation caused by microbial transfer from the vagina are believed to be important factors causing spontaneous preterm delivery (PTD). Multiple studies have examined the relationship between the cervicovaginal microbiome and spontaneous PTD with divergent results. Most studies have applied a DNA-based assessment, providing information on the microbial composition but not transcriptional activity. A transcriptomic approach was applied to investigate differences in the active vaginal microbiome and human transcriptome at midgestation between women delivering spontaneously preterm versus those delivering at term. Methods Vaginal swabs were collected in women with a singleton pregnancy at 18 + 0 to 20 + 6 gestational weeks. For each case of spontaneous PTD (delivery <37 + 0 weeks) two term controls were randomized (39 + 0 to 40 + 6 weeks). Vaginal specimens were subject to sequencing of both human and microbial RNA. Microbial reads were taxonomically classified using Kraken2 and RefSeq as a reference. Statistical analyses were performed using DESeq2. GSEA and HUMAnN3 were used for pathway analyses. Results We found 17 human genes to be differentially expressed (false discovery rate, FDR < 0.05) in the preterm group (n = 48) compared to the term group (n = 96). Gene expression of kallikrein-2 (KLK2), KLK3 and four isoforms of metallothioneins 1 (MT1s) was higher in the preterm group (FDR < 0.05). We found 11 individual bacterial species to be differentially expressed (FDR < 0.05), most with a low occurrence. No statistically significant differences in bacterial load, diversity or microbial community state types were found between the groups. Conclusions In our mainly white population, primarily bacterial species of low occurrence were differentially expressed at midgestation in women who delivered preterm versus at term. However, the expression of specific human transcripts including KLK2, KLK3 and several isoforms of MT1s was higher in preterm cases. This is of interest, because these genes may be involved in critical inflammatory pathways associated with spontaneous PTD
Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus erythematosus
BACKGROUND: An increased risk of pregnancy complications is seen in women with systemic lupus erythematosus (SLE), but the specific immunopathological drivers are still unclear. Hallmarks of SLE are granulocyte activation, type I interferon (IFN) overproduction, and autoantibodies. Here we examined whether low-density granulocytes (LDG) and granulocyte activation increase during pregnancy, and related the results to IFNα protein levels, autoantibody profile, and gestational age at birth. METHODS: Repeated blood samples were collected during pregnancy in trimesters one, two, and three from 69 women with SLE and 27 healthy pregnant women (HC). Nineteen of the SLE women were also sampled late postpartum. LDG proportions and granulocyte activation (CD62L shedding) were measured by flow cytometry. Plasma IFNα protein concentrations were quantified by single molecule array (Simoa) immune assay. Clinical data were obtained from medical records. RESULTS: Women with SLE had higher LDG proportions and increased IFNα protein levels compared to HC throughout pregnancy, but neither LDG fractions nor IFNα levels differed during pregnancy compared to postpartum in SLE. Granulocyte activation status was higher in SLE relative to HC pregnancies, and it was increased during pregnancy compared to after pregnancy in SLE. Higher LDG proportions in SLE were associated with antiphospholipid positivity but not to IFNα protein levels. Finally, higher LDG proportions in trimester three correlated independently with lower gestational age at birth in SLE. CONCLUSION: Our results suggest that SLE pregnancy results in increased peripheral granulocyte priming, and that higher LDG proportions late in pregnancy are related to shorter pregnancy duration but not to IFNα blood levels in SLE
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