Playing In Between: Patents’ Brokers In Markets For Technology

We here argue that patent brokers do not only stay in between supply and demand of innovation, but play in between executing complex transactions and taking entrepreneurial risk. In doing so they serve a support function to R&D managers of firms adopting various approaches to technological change. We discuss how economic and sociological theories explain brokerage and its existence. Our qualitative analysis of the current practice of patent brokerage in the U.S. finds only partial evidence in support of such argumentations. We conclude with our own proposition, suggesting that even in very dense environments, the bridging role of intellectual property intermediaries is that of market makers, who leverage their specific investment to play in between technology demand and supply.Open Innovation intermediaries patents intellectual property

Models of information systems devoted to medical-imaging labs: an experience in the CNR clinical physiology institute

At the end of the 1990s, the SPERIGEST project, supported by the Italian Health Ministry, and fully developed at the Institute of Clinical Physiology, established an operative integrated clinical and healthcare information system. Continuously evolving and dynamically optimising procedures and protocols solve problems of: harmonisation of instrumentation of different brands; management of multimedia data provided by different medical imaging labs; satisfaction of both clinical and research needs; legal and economical requirements; user-friendship of the system. A ten years experience shows positive approach by medical and healthcare operators, coordinated activity, higher efficiency, simplified procedures, major concentration on medical decision-making

Information systems for medical imaging labs: the experience of the CNR Clinical Physiology Institute

In the late 1990s the CNR Clinical Physiology Institute was entrusted with the "SPERIGEST" project, granted by the Italian Health Ministry. Among the technical challenges of the project, the following issues were faced: 1) the definition of a system architecture able to conjugate a centric view, as required by data integration needs, with flexibility and modularity in order to satisfy the different healthcare environments; 2) the creation of local information systems devoted to the management of each single laboratory activity; 3) the creation of a suitable network to exchange information both inside and outside the hospital; 4) the overcoming of safety and security issues in the treatment of healthcare data; 5) the data processing for extracting knowledge from the archived data and for supporting the diagnostic/treatment process; 6) the education of healthcare personnel; 7) the adoption of standards for both storage and distribution of data. An hospital information system was developed according to a three layers mode

Information systems for the management of clinical, administrative and government data of clinical imaging laboratories

Integrated network-based medical information systems are in continuous development an d evolution, furthered by the ongoing technology: the aim is to limit healthcare expend iture, while facing the increase of the demand of health services, as a result of the improvement of socialeconomic conditions, ageing of the population, and progress in medical knowledge and technologies. Today the discipline of OHealth Informaticso takes care of the design and the impleme ntation of information systems, to provide to the organization, processing, integration, storage, distribution and management, of the clinical and administrative data

Labelled Proofs For Quantified Modal Logic

We propose to extend description logic with defeasible rules, and to use the inferential mechanism of defeasible logic to reason with description logic constructors

Models of Information Systems devoted to Medical Imaging Labs: an experience in the CNR Clinical Physiology Institute

abstract for the paper presentation about the decennal experience at IFC on information systems developped for medical imaging labsabstract per la presentazione relativa alla decennale esperienza presso IFC sui sistemi informativi sviluppati per uso dei laboratori dedicati all\u27imaging clinico e di ricerca medic

Information systems for medical imaging labs: the experience of the CNR Clinical Physiology Institute

Local information systems, devoted to the management of the clinical and healthcare activity in laboratories for biomedical imaging, has been realized in IFC. Herein is a presentation of the main results obtained after a ten years development and employment of such a complex information system

Information Systems for the Management of Clinical, Administrative and Government Data of Clinical Imaging Laboratories

The integrated clinical and healthcare information system, developed at the CNR Clinical Physiology Institute, undergoes to updated and upgraded procedures and protocols, by solving problems of: harmonization of instrumentation of different brands; management of multimedial data provided by different medical imaging labs; satisfaction of both clinical and research needs as well as legal and economical requirements; user-friendship of the provided tools. Peculiar attention has been paid to the management of the laboratories devoted to biomedical imaging: medical and healthcare operators have coworked with engineers, to get a system able to guarantee coordinated activity, higher efficiency, simplified procedures, major concentration onto the medical decision-making issues, by supporting conventional techniques as well as new hybrid imaging technologies.Il sistema informativo per uso clinico e sanitario, sviluppato presso l\u27Istituto di Fisiologia Clinica del CNR, e\u27 in continuo aggiornamento e sviluppo di procedure e protocolli, che risolvano problemi relativi a: armonizzazione di strumentazione prodotta da diversi marchi commerciali e non; gestione dei dati multimediali forniti dai vari laboratori di imaging clinico; soddisfazione delle esigenze di ricerca e cliniche nonche\u27 deei requisiti di legalita\u27 ed economicita\u27; facilita\u27 d\u27uso degli strumenti proposti all\u27utente. Particolare attenzione e\u27 stata dedicata al "governo" dei laboratori di imaging medicale, e i vari operatori sanitari hanno collaborato con quelli tecnologici per realizzare un sistema capace di garantire un\u27attivita\u27 coordinata, piu\u27 elevata efficienza, procedure semplificate, maggiore concentrazione sulla "decisione" medica, sia dando sostegno alle tradizionali tecniche di acquisizione che alle innovative tecniche ibride

Production of pectinases by <i>A. niger</i>: Influence of fermentation conditions

Response surface methodology was used for optimization of polygalacturonase (PG) and pectinesterase (PE) production in submerged fermentation by A.niger. A Central Composite Experimental Design was applied, consisting of 22 experiments, including eight central points. Variables studied were: fermentation time (24 to 120 h), pH (3.5 to 6.5) and initial concentration of pectin (5 to 20 g/l). Maximum PE production was 220 U/l, after 74 h of culture, in a medium containing 20 g/l of pectin (pH 6.5). The optimal conditions for PG production were pH: 4.1, 20 g/l of pectin and 94 h of fermentation with a maximum value of 1032 U/l. Under these conditions, the PE production was low (15 U/l). A liquid extract with high PG activity and low PE activity could be suitable to be used in food processing in order to reduce the production of methanol.Facultad de Ciencias Exacta

Production of pectinases by <i>A. niger</i>: Influence of fermentation conditions

Response surface methodology was used for optimization of polygalacturonase (PG) and pectinesterase (PE) production in submerged fermentation by A.niger. A Central Composite Experimental Design was applied, consisting of 22 experiments, including eight central points. Variables studied were: fermentation time (24 to 120 h), pH (3.5 to 6.5) and initial concentration of pectin (5 to 20 g/l). Maximum PE production was 220 U/l, after 74 h of culture, in a medium containing 20 g/l of pectin (pH 6.5). The optimal conditions for PG production were pH: 4.1, 20 g/l of pectin and 94 h of fermentation with a maximum value of 1032 U/l. Under these conditions, the PE production was low (15 U/l). A liquid extract with high PG activity and low PE activity could be suitable to be used in food processing in order to reduce the production of methanol.Facultad de Ciencias Exacta