21 research outputs found
Molecular characterization of novel Cryptosporidium fish genotypes in edible marine fish
Current knowledge of Cryptosporidium species/genotypes in marine fish is limited. Following phylogenetic analysis at the 18S rDNA locus, a recent study identified six new genotypes of Cryptosporidium colonizing edible fish found in European seas. Of these, five grouped in a clade together (#Cryptofish 1–5) and one grouped separately (#Cryptofish 7). In the present study, after phylogenetic analyses of #Cryptofish1, #Cryptofish2, #Cryptofish4, #Cryptofish5 and #Cryptofish7 at the actin locus, the presence of two major clades was confirmed. In addition, when possible, longer 18S amplicons were generated. In conclusion, the small genetic distances between these genotypes designated as a novel marine genotype I (#Cryptofish 1-5) suggest that they may be genetic variants of the same species, while the designated novel marine genotype 2 (#Cryptofish 7) is clearly representative of a separate species
Cancer and parasitic infections: similarities and opportunities for the development of new control tools
La cryptosporidiose et son impact en santé publique
International audienceCryptosporidium est une cause majeure de diarrhée à travers le monde et l’infection par ce parasite touche en particulier les jeunes enfants et les patients immunodéprimés. La gravité de l’infection intestinale induite par ce protozoaire intracellulaire est variable et les symptômes cliniques de la cryptosporidiose dépendent non seulement de l'état nutritionnel et immunitaire de l'hôte mais également des facteurs de virulence du parasite. L’infection humaine résulte d’une propagation zoonotique (de l’animal à l’Homme) ou anthroponotique (inter-humaine) du parasite dont la transmission est facilitée par sa résistance aux nombreux désinfectants couramment utilisés. Les mesures de prévention et de contrôle de l’infection sont capitales pour la protection des groupes vulnérables car les options de traitement restent encore limitée
La cryptosporidiose et son impact en santé publique
International audienceCryptosporidium est une cause majeure de diarrhée à travers le monde et l’infection par ce parasite touche en particulier les jeunes enfants et les patients immunodéprimés. La gravité de l’infection intestinale induite par ce protozoaire intracellulaire est variable et les symptômes cliniques de la cryptosporidiose dépendent non seulement de l'état nutritionnel et immunitaire de l'hôte mais également des facteurs de virulence du parasite. L’infection humaine résulte d’une propagation zoonotique (de l’animal à l’Homme) ou anthroponotique (inter-humaine) du parasite dont la transmission est facilitée par sa résistance aux nombreux désinfectants couramment utilisés. Les mesures de prévention et de contrôle de l’infection sont capitales pour la protection des groupes vulnérables car les options de traitement restent encore limitée
Parasites and malignancies, a review, with emphasis on digestive cancer induced by Cryptosporidium parvum (Alveolata: Apicomplexa)
The International Agency for Research on Cancer (IARC) identifies ten infectious agents (viruses, bacteria, parasites) able to induce cancer disease in humans. Among parasites, a carcinogenic role is currently recognized to the digenetic trematodes Schistosoma haematobium, leading to bladder cancer, and to Clonorchis sinensis or Opisthorchis viverrini, which cause cholangiocarcinoma. Furthermore, several reports suspected the potential association of other parasitic infections (due to Protozoan or Metazoan parasites) with the development of neoplastic changes in the host tissues. The present work shortly reviewed available data on the involvement of parasites in neoplastic processes in humans or animals, and especially focused on the carcinogenic power of Cryptosporidium parvum infection. On the whole, infection seems to play a crucial role in the etiology of cancer.Le Centre International de Recherche sur le Cancer (CIRC) recense
dix agents infectieux (virus, bactéries, parasites) responsables
de pathologies cancéreuses chez l’homme. Parmi les parasites
actuellement reconnus comme cancérogènes figurent les
trématodes digénétiques Schistosoma haematobium, agent de
cancer vésical, Clonorchis sinensis et Opisthorchis viverrini, agents
de cholangiocarcinome. Par ailleurs, plusieurs rapports suspectent
l’association potentielle entre d’autres infections parasitaires (Ă
protistes ou à métazoaires) et le développement de changements
néoplasiques dans les tissues de l’hôte. Cette revue propose une vue
d’ensemble des données disponibles sur les relations entre parasites
et processus néoplasiques chez l’homme et autres animaux. À la
lumière de découvertes récentes, le cas de Cryptosporidium parvum
fait l’objet d’une analyse plus approfondie. Globalement, les
infections semblent jouer un rôle crucial dans l’étiologie du cance
Parasites and malignancies, a review, with emphasis on digestive cancer induced by
The International Agency for Research on Cancer (IARC) identifies ten infectious agents (viruses, bacteria, parasites) able to induce cancer disease in humans. Among parasites, a carcinogenic role is currently recognized to the digenetic trematodes Schistosoma haematobium, leading to bladder cancer, and to Clonorchis sinensis or Opisthorchis viverrini, which cause cholangiocarcinoma. Furthermore, several reports suspected the potential association of other parasitic infections (due to Protozoan or Metazoan parasites) with the development of neoplastic changes in the host tissues. The present work shortly reviewed available data on the involvement of parasites in neoplastic processes in humans or animals, and especially focused on the carcinogenic power of Cryptosporidium parvum infection. On the whole, infection seems to play a crucial role in the etiology of cancer
Parasites and malignancies, a review, with emphasis on digestive cancer induced by Cryptosporidium parvum (Alveolata: Apicomplexa)
The International Agency for Research on Cancer (IARC) identifies ten infectious agents (viruses, bacteria, parasites) able to induce cancer disease in humans. Among parasites, a carcinogenic role is currently recognized to the digenetic trematodes Schistosoma haematobium, leading to bladder cancer, and to Clonorchis sinensis or Opisthorchis viverrini, which cause cholangiocarcinoma. Furthermore, several reports suspected the potential association of other parasitic infections (due to Protozoan or Metazoan parasites) with the development of neoplastic changes in the host tissues. The present work shortly reviewed available data on the involvement of parasites in neoplastic processes in humans or animals, and especially focused on the carcinogenic power of Cryptosporidium parvum infection. On the whole, infection seems to play a crucial role in the etiology of cancer