file2. Parallel to bedding

The table contains series of measurements for Megathrix longus in thin sections parallel to the bedding

file3. measurements on selected trichomes

This table contains measurements on the selected trichomes with consistent diameter (67–70 μm). From these data, we can get the positive linear correlation of complete cross-walls spacing and the intercalated incomplete cross-walls length

The results of subgroup analyses for the outcomes of identification rate and crossover rate during SLNB, respectively.

<p>The results of subgroup analyses for the outcomes of identification rate and crossover rate during SLNB, respectively.</p

Forest plots of the pooled identification rate of ARM nodes or lymphatics, and crossover rate of ARM-SLN nodes during SLNB.

<p>(A) the identification rate of ARM nodes or lymphatics; (B) the crossover rate of ARM-SLN nodes during SLNB.</p

Forest plot of the pooled incidence of lymphedema, which was stratified by different procedures.

<p>Forest plot of the pooled incidence of lymphedema, which was stratified by different procedures.</p

Forest plots of the association between preoperative neoadjuvant chemotherapy, axillary status and the risk of ARM metastasis.

<p>(A) preoperative neoadjuvant chemotherapy; (B) axillary status.</p

Forest plot of the pooled identification rate of ARM nodes or lymphatics during ALND.

<p>Forest plot of the pooled identification rate of ARM nodes or lymphatics during ALND.</p

Forest plot of the pooled rate of metastasis in resected ARM nodes.

<p>Forest plot of the pooled rate of metastasis in resected ARM nodes.</p

Light-Stimulated Synaptic Devices Utilizing Interfacial Effect of Organic Field-Effect Transistors

Synaptic transistors stimulated by light waves or photons may offer advantages to the devices, such as wide bandwidth, ultrafast signal transmission, and robustness. However, previously reported light-stimulated synaptic devices generally require special photoelectric properties from the semiconductors and sophisticated device’s architectures. In this work, a simple and effective strategy for fabricating light-stimulated synaptic transistors is provided by utilizing interface charge trapping effect of organic field-effect transistors (OFETs). Significantly, our devices exhibited highly synapselike behaviors, such as excitatory postsynaptic current (EPSC) and pair-pulse facilitation (PPF), and presented memory and learning ability. The EPSC decay, PPF curves, and forgetting behavior can be well expressed by mathematical equations for synaptic devices, indicating that interfacial charge trapping effect of OFETs can be utilized as a reliable strategy to realize organic light-stimulated synapses. Therefore, this work provides a simple and effective strategy for fabricating light-stimulated synaptic transistors with both memory and learning ability, which enlightens a new direction for developing neuromorphic devices

Akt-Signal Integration Is Involved in the Differentiation of Embryonal Carcinoma Cells

<div><p>The mechanism by which Akt modulates stem cell homeostasis is still incompletely defined. Here we demonstrate that Akt phosphorylates <u>s</u>pecial <u>AT</u>-rich sequences <u>b</u>inding protein 1 (SATB1) at serine 47 and protects SATB1 from apoptotic cleavage. Meanwhile, Akt phosphorylates Oct4 at threonine 228 and Klf4 at threonine 399, and accelerates their degradation. Moreover, PI3K/Akt signaling enhances the binding of SATB1 to Sox2, thereby probably impairing the formation of Oct4/Sox2 regulatory complexes. During retinoic acid (RA)-induced differentiation of mouse F9 embryonal carcinoma cells (ECCs), the Akt activation profile as well as its substrate spectrum is strikingly correlated with the down-regulation of Oct4, Klf4 and Nanog, which suggests Akt activation is coupled to the onset of differentiation. Accordingly, Akt-mediated phosphorylation is crucial for the capability of SATB1 to repress Nanog expression and to activate transcription of <i>Bcl2</i> and <i>Nestin</i> genes. Taken together, we conclude that Akt is involved in the differentiation of ECCs through coordinated phosphorylations of pluripotency/differentiation factors.</p></div