Ontogenetically-regulated male sterility in tissue culture - induced and spontaneous sorghum mutants

Variability of male fertility expression in the AS-1 line, a somaclonal variant obtained from tissue culture of CMS-plant, and in the progeny of revenant '124-1' obtained from fertile tiller, which developed on CMS-plant transferred from the field to the greenhouse, was investigated. Both revertants were characterized by similar expression of male fertility during plant ontogenesis: the panicle on the main tiller was almost completely sterile whereas formation of fertile pollen grains and seed set were observed on the panicles of the shoot tillers. A clear basipetal gradient of male fertility was manifested on all panicles: the base had significantly higher per cent of fertile pollen grains in comparison with the middle part, while in the top the anthers were either absent or had few sterile pollen grains. Such an ontogenetically-regulated restoration of male fertility was controlled by nuclear genes and could be transferred through the pollen in crosses with progenitor CMS-line. Growing of AS-1 plants in the growth chambers simultaneously under a long (16/8) and a short (12/12) daylength conditions demonstrated that differences of fertility level in different tillers was not caused by change of photoperiod during plant ontogenesis and functioning of photoperiod-sensitive fertility restoring gene. Whereas, the ontogenetically-regulated expression of male fertility in both revenants was temperature-dependent and was clearly manifested under relatively cool conditions during 2-week period before the beginning of anthesis of the first panicle (average daily temperature 21°C). The increase of the average daily temperature by 2-3 С resulted in sharp increase of male fertility level. Possibility of using AS-1 line in a new "two-line system" of hybrid seed production, which require only two lines (sterile mutant and fertility restorer), is discussed

POLLINOSES IN CHILDREN AND ADOLESCENTS

The problem of pollinoses in children and adolescens are disacussed in the article on the basis of own investigations and the date of literature. The ussues of etiology, pathogenesis pollinoses, as clinic, diet therapy, pharmacotherapy are disacussed by authors in this work. It is shown, that allergen speacific immunotherapy posesses with high effectivenes in children and adolescents, suffering from pollen sensitization diseases.Key words: pollinoses, allergen specific immunotherapy, children, adolescens

POLLINOSES IN CHILDREN AND ADOLESCENTS

The problem of pollinoses in children and adolescens are disacussed in the article on the basis of own investigations and the date of literature. The ussues of etiology, pathogenesis pollinoses, as clinic, diet therapy, pharmacotherapy are disacussed by authors in this work. It is shown, that allergen speacific immunotherapy posesses with high effectivenes in children and adolescents, suffering from pollen sensitization diseases.Key words: pollinoses, allergen specific immunotherapy, children, adolescens

Pade-approximation as a "bridge" between two parametric boundary asymptotics

For classical optimal control problem with free right end point and two groups of motions in one of which velocity has both large and small values is constructed approximate analytic expressions for optimal control based on Pade-approximation. It is instinctively clear that weakly controllable systems and systems with hign-gain coefficient are connected by some parametric "bridge" even though the contrary valuations of parameter. Copyright (C) 2001 IFAC

Pade-approximation as a "bridge" between two parametric boundary asymptotics

For classical optimal control problem with free right end point and two groups of motions in one of which velocity has both large and small values is constructed approximate analytic expressions for optimal control based on Pade-approximation. It is instinctively clear that weakly controllable systems and systems with hign-gain coefficient are connected by some parametric "bridge" even though the contrary valuations of parameter. Copyright (C) 2001 IFAC

HIV infection risk perception and stigmatizing attitude: Results of surveys of dwellers from the Central Administrative District of Moscow

Aim. To study human immunodeficiency virus (HIV) infection risk perception and stigmatizing attitudes in the dwellers of the Central Administrative District of Moscow. Subjects and methods. An anonymous survey was conducted using specially developed questionnaires. A total of 893 people were interviewed. Each of the given indicators was used to ask 98 to 254 respondents. Among the survey participants, there were 92 healthcare workers, including 66 physicians and 26 representatives of middle-level and junior medical staff. According to their replies, the respondents were divided into 2 groups: 1) healthcare workers; 2) representatives of the so-called general population. Results. 91.3% of the healthcare workers gave a negative reply to the question: "Should contacts (intercourse) with people living with HIV (AIDS) be avoided to escape infection?". In Group 2, 58.8 and 23.5% of the respondents answered negatively and positively, respectively; and 17.6% had difficulty answering the question. In the general population group, 44.1% of the respondents answered negatively and 32.2% had difficulty answering the question: "Would you agree to live in the same room with anybody whom you know or suspect to be HIV positive?"; 23.8% agreed to do this. Among the healthcare workers, there were 46.7% of the respondents who answered positively. When the question: "Would you agree to send your child (grandson) to the kindergarten if you would learn that a HIV-infected child goes there?" was asked, 48.6 and 18.7% of the respondents in the general population group answered negatively and positively, respectively; 32.7% had difficulty answering. In the group of healthcare workers, 66.7% answered positively. Among both the healthcare workers and the representatives of the general population, more than 60% of the respondents agreed with the statement that "HIV-infected people lead a loose life". Conclusion. The specific features of perceiving a HIV infection risk and showing stigmatizing attitudes towards HIV-infected patients make the forming less dangerous behaviors difficult and restrict an access to care and support in infected patients. The training of healthcare workers in issues related to HIV infection should involve the identification of stigmatizing attitudes and the application of destigmatization strategies

HIV infection risk perception and stigmatizing attitude: Results of surveys of dwellers from the Central Administrative District of Moscow

Aim. To study human immunodeficiency virus (HIV) infection risk perception and stigmatizing attitudes in the dwellers of the Central Administrative District of Moscow. Subjects and methods. An anonymous survey was conducted using specially developed questionnaires. A total of 893 people were interviewed. Each of the given indicators was used to ask 98 to 254 respondents. Among the survey participants, there were 92 healthcare workers, including 66 physicians and 26 representatives of middle-level and junior medical staff. According to their replies, the respondents were divided into 2 groups: 1) healthcare workers; 2) representatives of the so-called general population. Results. 91.3% of the healthcare workers gave a negative reply to the question: "Should contacts (intercourse) with people living with HIV (AIDS) be avoided to escape infection?". In Group 2, 58.8 and 23.5% of the respondents answered negatively and positively, respectively; and 17.6% had difficulty answering the question. In the general population group, 44.1% of the respondents answered negatively and 32.2% had difficulty answering the question: "Would you agree to live in the same room with anybody whom you know or suspect to be HIV positive?"; 23.8% agreed to do this. Among the healthcare workers, there were 46.7% of the respondents who answered positively. When the question: "Would you agree to send your child (grandson) to the kindergarten if you would learn that a HIV-infected child goes there?" was asked, 48.6 and 18.7% of the respondents in the general population group answered negatively and positively, respectively; 32.7% had difficulty answering. In the group of healthcare workers, 66.7% answered positively. Among both the healthcare workers and the representatives of the general population, more than 60% of the respondents agreed with the statement that "HIV-infected people lead a loose life". Conclusion. The specific features of perceiving a HIV infection risk and showing stigmatizing attitudes towards HIV-infected patients make the forming less dangerous behaviors difficult and restrict an access to care and support in infected patients. The training of healthcare workers in issues related to HIV infection should involve the identification of stigmatizing attitudes and the application of destigmatization strategies

ПОЛЛИНОЗЫ У ДЕТЕЙ И ПОДРОСТКОВ

The problem of pollinoses in children and adolescens are disacussed in the article on the basis of own investigations and the date of literature. The ussues of etiology, pathogenesis pollinoses, as clinic, diet therapy, pharmacotherapy are disacussed by authors in this work. It is shown, that allergen speacific immunotherapy posesses with high effectivenes in children and adolescents, suffering from pollen sensitization diseases.Key words: pollinoses, allergen specific immunotherapy, children, adolescens.В работе на основе собственных исследований и анализа данных литературы освещена проблема поллиноза у детей и подростков. Рассмотрены вопросы этиологии и патогенеза поллиноза, клиниa ческих проявлений, диетоa и фармакотерапии у детей и подростков, показана высокая эффективa ность методов аллергенспецифической иммунотерапии при аллергических болезнях, обусловленa ных пыльцевой сенсибилизацией.Ключевые слова: поллинозы, аллергенспецифическая иммунотерапия, дети, подростки.(Педиатрическая фармакология. – 2007;4(2):66-70