81 research outputs found
Eating with Type: Designing a Letterpress Workshop Based on Typeful Thinking Approach for Food Education
Starting from the observation of an evident precariousness in the contemporary relationship between man and food, this contribution is meant to show a new proposal of workshops for children in the K=12, Grade 4–5 category, aimed at stimulating in a creative and experiential way a critical and conscious thinking about food. Starting from the methodology of Artful Thinking and Object Based Learning, the project shifts the pedagogical focus from the interaction with the artistic object to the interaction with the design object; and in particular with the movable type, identified as an activating element of the educational process in the transition from Artful to Typeful Thinking. The Typeful Thinking workshop therefore represents a potentially innovative food education tool that leverages on the concretisation of critical thinking through five thinking routines that go from conceptual abstraction - through a physical artefact, the letterpress printing - to their tangibility
Eating with Type. Designing a Letterpress Workshop Based on Typeful Thinking Approach for Food Education
Starting from the observation of an evident precariousness in the contemporary relationship between man and food, this contribution is meant to show a new proposal of workshops for children in the K=12, Grade 4–5 category, aimed at stimulating in a creative and experiential way a critical and conscious thinking about food. Starting from the methodology of Artful Thinking and Object Based Learning, the project shifts the pedagogical focus from the interaction with the artistic object to the interaction with the design object; and in particular with the movable type, identified as an activating element of the educational process in the transition from Artful to Typeful Thinking. The Typeful Thinking workshop therefore represents a potentially innovative food education tool that leverages on the concretisation of critical thinking through five thinking routines that go from conceptual abstraction —through a physical artefact, the letterpress printing— to their tangibility
Conservative Versus Surgical Management of Elbow Medial Ulnar Collateral Ligament Injury: A Systematic Review
Objective: Several studies have been published regarding the treatment of medial ulnar collateral ligament (MUCL) injuries for professional overhead athletes. However, there is a paucity of data regarding non-professional athletes. The aim of this systematic review was to compare the rate of outcome scores and complications of conservative versus operative treatments both in non-professional athletes and in non-sport-related trauma patients with MUCL lesions. Methods: A systematic review of the published literature was performed by applying the PRISMA guidelines. A search was conducted using three databases: Medline, Science Direct, and Web of Science. The keywords used were \u201culnar collateral ligament injury,\u201d \u201celbow,\u201d \u201csurgery,\u201d and \u201cconservative treatment\u201d. Patients were divided into three groups: patients who underwent conservative treatment (C-group), surgical treatment (S-group), and surgery after a failed conservative treatment (C&S-group). Clinical outcomes were analyzed: Disability of Arm, Shoulder and Hand (DASH), Conway scale, Carson score, and Kerlan\u2013Jobe Orthopaedic Clinic score (KJOC). Results: A total of 15 studies were included, evaluating 513 patients. Although good and excellent outcomes were found for most patients during daily and/or sport activities, independently of the type of treatment, the C-group had better results. Excellent results were found in 98.8% of the C-group, in 88.1% of the S-group, and in 87.7% of the C&S-group. The complication rate in the C-group was statistically higher compared to the S and C&S groups (P < 0.001). However, its complication rate was higher with lower patient satisfaction. Conclusions: There is insufficient evidence to establish statistically significant differences in the effects of conservative versus surgical treatments on the functional outcomes of patients with MUCL lesions. However, a period of rehabilitation therapy and the functional request of the single injured subject are useful to discern which patients genuinely require MUCL surgical repair
Symptomatic pseudoarthrosis secondary to a stress fracture of the acromion
Summary. Fractures of the acromion are uncommon clinical entities, and stress fractures are even more rare, with few cases reported. Due to their rarity, stress fractures are often misdiagnosed. Here, we report a case of an elderly patient with an acromion stress fracture, which was overlooked, resulting in nonunion followed by the displacement of the distal portion of the acromion. The purpose of this report was to discuss this rare fracture, highlighting the importance of an accurate evaluation of radiological imaging as well as clinical data
A new iron free treatment with oral fi sh cartilage polysaccharide for iron defi ciency chronic anemia in infl ammatory bowel diseases: A pilot study
Abstract AIM: To investigate the effect of a new oral preparation, highly concentrated in fish cartilage, in a group of infl ammatory bowel diseases (IBD) patients with chronic iron defi cient anemia. METHODS: In an open label pilot study, we supplemented a group of 25 patients (11 with Crohn's disease and 14 with ulcerative colitis) in stable clinical conditions and chronic anemia with a food supplement which does not contain iron but contains a standardized fraction of fish cartilage glycosaminoglycans and a mixture of antioxidants (Captafer Medestea, Turin, Italy). Patients received 500 mg, twice a day during meals, for at least 4 mo. Patients were suggested to maintain their alimentary habit. At time 0 and after 2 and 4 mo, emocrome, sideremia and ferritin were examined. Paired data were analyzed with Student's t test. RESULTS: Three patients relapsed during the study (2 in the 3 rd mo, 1 in the 4 th mo), two patients were lost to follow up and two patients dropped out (1 for orticaria, 1 for gastric burning). Of the remaining 18 patients, levels of serum iron started to rapidly increase within the 2 nd mo of treatment, P < 0.05), whereas serum ferritin and hemoglobin needed a longer period to signifi cantly improve their serum levels (mo 4) P < 0.05). The product was safe, easy to administer and well tolerated by patients. CONCLUSION: These data suggest a potential new treatment for IBD patients with iron defi ciency chronic anemia and warrant further larger controlled studies
A Mediterranean Diet Mix Has Chemopreventive Effects in a Murine Model of Colorectal Cancer Modulating Apoptosis and the Gut Microbiota
Objectives: Unhealthy dietary patterns have been associated with colorectal cancer (CRC) onset while Mediterranean Diet (MD) has been proposed for CRC prevention. This study evaluated the effect of a Mediterranean Diet Mix (MD-MIX) on colonic tumors development in A/J mice fed a low-fat (LFD) or a high-fat western diet (HFWD), and injected with the procarcinogen azoxymethane (AOM).Materials and Methods: Forty A/J male mice were randomly assigned into four feeding arms (10 mice/arm; LFD, LFD-MD-MIX, HFWD, HFWD-MD-MIX) to be treated with AOM. Ten mice were exposed to the diets alone (Healthy LFD and Healthy HFWD) to be used as control. Tumor incidence and multiplicity were evaluated at sacrifice. Mucosal fatty acid content and urinary phenolic compounds were assayed by mass spectrometry. Apoptosis was evaluated by TUNEL assay and gene expression markers. Cell proliferation was evaluated by Ki67 immunohistochemistry. Microbiota composition was assessed at different time points by 16S RNA sequencing.Results: A tumor incidence of 100% was obtained in AOM-treated mice. The MD-MIX supplementation was able to reduce the number of colonic lesions in both LFD and HFWD-fed mice and to induce apoptosis, in particular in the LFD-MD-MIX arm. Moreover, a preventive effect on low-grade dysplasia and macroscopical lesions (>1 mm) development was found in HFWD-fed mice together with a regulation of the AOM-driven intestinal dysbiosis.Conclusions: MD-MIX was able to counteract CRC development in mice under different dietary backgrounds through the regulation of apoptosis and gut microbiota
A new iron free treatment with oral fish cartilage polysaccharide for iron deficiency chronic anemia in inflammatory bowel diseases: A pilot study
The Imbalance between n-6/n-3 Polyunsaturated Fatty Acids and Inflammatory Bowel Disease: A Comprehensive Review and Future Therapeutic Perspectives
Eating habits have changed dramatically over the years, leading to an imbalance in the ratio of n-6/n-3 polyunsaturated fatty acids (PUFAs) in favour of n-6 PUFAs, particularly in the Western diet. Meanwhile, the incidence of inflammatory bowel disease (IBD) is increasing worldwide. Recent epidemiological data indicate the potential beneficial effect of n-3 PUFAs in ulcerative colitis (UC) prevention, whereas consumption of a higher ratio of n-6 PUFAs versus n-3 PUFAs has been associated with an increased UC incidence. The long-chain dietary n-3 PUFAs are the major components of n-3 fish oil and have been shown to have anti-inflammatory properties in several chronic inflammatory disorders, being involved in the regulation of immunological and inflammatory responses. Despite experimental evidence implying biological plausibility, clinical data are still controversial, especially in Crohn’s disease. Clinical trials of fish-oil derivatives in IBD have produced mixed results, showing beneficial effects, but failing to demonstrate a clear protective effect in preventing clinical relapse. Such data are insufficient to make a recommendation for the use of n-3 PUFAs in clinical practice. Here, we present the findings of a comprehensive literature search on the role of n-3 PUFAs in IBD development and treatment, and highlight new therapeutic perspectives
PROBABILISTIC ASSESSMENT OF SYMPTOMLESS INFLAMMATION IN CROHN\u2019S DISEASE PATIENTS
In Crohn\u2019s Disease it is extremely important to detect the presence of symptomless
mucosal inflammation in such a way as to prevent the evolution of the disease. The
aim of this study is to identify predictor variables for estimating the risk of the presence
of mucosal inflammation. The results show that the estimated model provides a clear
picture of the relationship among the selected predictors and the outcome of interest
and has a very appreciable ability for identifying patients at high risk of symptomless
but persistent inflammation
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