Wind loads analysis at the anchorages of the Talavera de la Reina cable stayed bridge

This paper describes wind tunnel tests performed on wind tunnel models of the Talavera de la Reina cable stayed bridge. The work describes the aeroelastic model construction and it is focused on the evaluation and analysis of the mean and peak wind loads at the tower foundation and the cable anchorages since these data can be very useful by the bridge manufacturer as a support for the bridge design. The work is part of a complete wind tunnel study carried out to analyze the aeroelastic stability of the bridge

Full scale monitoring of the twin chimneys of the rovinari power plant

The presented paper deals with the structural identification and monitoring of two twin chimneys in very close arrangement. Due to twin arrangement, important interference effects are expected to modify the chimney response to wind action, causing vortex shedding and state-dependent excitation associated to the oscillatory motion of the leeward chimney, in and out of the windward chimney wake. The complexity of the physics of this problem is increased by the dependency of the aerodynamics of circular cylinders on Reynolds number; however, there is a weakness of literature about cylinders behaviour at critical and super-critical range of Reynolds number, due to experimental limitations. Also the International Committee on Industrial Chimneys (CICIND) does not provide, at present, any specific technical guideline about twin chimneys whose interaxis distance is less or equal two times the diameter, as in this case. For this reason a Tuned Mass Damper (TMD) has been installed in order to increase the damping of the chimney, as merely suggested. This work aims at assessing the effectiveness of the installed TMD and characterizing the tower dynamic behaviour itself due to the wind excitation, as well as providing full scale measurements for twin cylinders configuration at high Reynolds numbers

Adding aerodynamic damping: the wing design for the Third Bosphorus Bridge

This paper is about the design of wing profiles adequate for giving to the Third Bosphorus Brige an additional aerodynamic damping on both vertical bending as well as torsional modes. The additional damping estimate procedure is made through a simplified quasi steady approach. A CFD approach has been used for a preliminary design and optimization of the wing profile and its position over the wind screen at the upwind and downwind location

Mate Marote: a BigData platform for massive scale educational interventions

In this paper we present Mate Marote, a web platform for massive scale educational interventions. We focus on the scaling requirements needed on these kind of deployments. We show the designed architecture, how these decisions solve the imposed requirements and the implementation. To test this development, we performed a small pilot intervention where the whole system was evaluated. We conclude that Mate Marote is ready for production deployment and enabled to middleto- massive scale interventions. For this purpose, we have deployed this platform in CEIBAL program at Uruguay with more than 100K potential users.Sociedad Argentina de Informática e Investigación Operativ

Mate Marote: a BigData platform for massive scale educational interventions

In this paper we present Mate Marote, a web platform for massive scale educational interventions. We focus on the scaling requirements needed on these kind of deployments. We show the designed architecture, how these decisions solve the imposed requirements and the implementation. To test this development, we performed a small pilot intervention where the whole system was evaluated. We conclude that Mate Marote is ready for production deployment and enabled to middleto- massive scale interventions. For this purpose, we have deployed this platform in CEIBAL program at Uruguay with more than 100K potential users.Sociedad Argentina de Informática e Investigación Operativ

On the functional design of the DTU10 MW wind turbine scale model of LIFES50+ project

This paper illustrates the mechatronic design of the wind tunnel scale model of the DTU 10MW reference wind turbine, for the LIFES50+ H2020 European project. This model was designed with the final goal of controlling the angle of attack of each blade by means of miniaturized servomotors, for implementing advanced individual pitch control (IPC) laws on a Floating Offshore Wind Turbine (FOWT) 1/75 scale model. Many design constraints were to be respected: among others, the rotor-nacelle overall mass due to aero-elastic scaling, the limited space of the nacelle, where to put three miniaturized servomotors and the main shaft one, with their own inverters/controllers, the slip rings for electrical rotary contacts, the highest stiffness as possible for the nacelle support and the blade-rotor connections, for ensuring the proper kinematic constraint, considering the first flapwise blade natural frequency, the performance of the servomotors to guarantee the wide frequency band due to frequency scale factors, etc. The design and technical solutions are herein presented and discussed, along with an overview of the building and verification process. Also a discussion about the goals achieved and constraints respected for the rigid wind turbine scale model (LIFES50+ deliverable D.3.1) and the further possible improvements for the IPC-aero-elastic scale model, which is being finalized at the time of this paper

Minimal inhibitory and Mutant prevention concentrations of enrofloxacin for Pasteurella multocida from rabbits affected by pasteurellosis

Pasteurella multocida is the agent of one of the most significant diseases in rabbits and it is associated with a heterogeneous clinical picture. Drugs belonging to the fluoroquinolones class are useful to control pasteurellosis. Among them, enrofloxacin is one of the most used molecules in rabbit industry and it is the only one fluoroquinolone registered for this species in Italy. Enrofloxacin adopted dosages are currently based on Minimum Inhibitory Concentration (MIC). Nevertheless, MIC is not effective against possible pathogen sub-populations with lower susceptibility that may be selectively amplified, leading to possible problems of antibiotic resistance. Mutant Prevention Concentration (MPC) could represent an approach to minimize the risk of resistance selection in pathogens. The aim of this work was to test the sensitivity to enrofloxacin of P. multocida strains isolated from rabbits affected by pasteurellosis to evaluate if MPC-based dosages can represent a valid option. The study was performed on ten strains of P. multocida isolated from rabbits from two industrial farms of Puglia, South Italy. The sensitivity to enrofloxacin has been evaluated by MIC tests by microdilution method and MPC tests performed according to Marcusson et al. (2005) with minor modifications. The results of MIC and MPC tests have revealed that MPC dosages are on average 8,4 times higher than MIC dosages. This data highlight that, although MPC-based dosages are useful to prevent the selection of potential mutant, they could be higher than MIC-based ones, leading to possible issues related to their application in field, for example the potential risk of possible toxicity for animals and residues in meat

Elevated n-terminal pro-brain natriuretic peptide is associated with mortality in tobacco smokers independent of airflow obstruction

Background: Tobacco use is associated with an increased prevalence of cardiovascular disease. N-terminal pro-brain natiuretic peptide (NT-proBNP), a widely available biomarker that is associated with cardiovascular outcomes in other conditions, has not been investigated as a predictor of mortality in tobacco smokers. We hypothesized that NT-proBNP would be an independent prognostic marker in a cohort of well-characterized tobacco smokers without known cardiovascular disease. Methods: Clinical data from 796 subjects enrolled in two prospective tobacco exposed cohorts was assessed to determine factors associated with elevated NT-proBNP and the relationship of these factors and NT-proBNP with mortality. Results: Subjects were followed for a median of 562 (IQR 252 - 826) days. Characteristics associated with a NT-proBNP above the median (≥49 pg/mL) were increased age, female gender, and decreased body mass index. By time-to-event analysis, an NT-proBNP above the median (≥49 pg/mL) was a significant predictor of mortality (log rank p = 0.02). By proportional hazard analysis controlling for age, gender, cohort, and severity of airflow obstruction, an elevated NT-proBNP level (≥49 pg/mL) remained an independent predictor of mortality (HR = 2.19, 95% CI 1.07-4.46, p = 0.031). Conclusions: Elevated NT-proBNP is an independent predictor of mortality in tobacco smokers without known cardiovascular disease, conferring a 2.2 fold increased risk of death. Future studies should assess the ability of this biomarker to guide further diagnostic testing and to direct specific cardiovascular risk reduction inventions that may positively impact quality of life and survival. © 2011 Stamm et al