6,034 research outputs found
Magnifying perfect lens and superlens design by coordinate transformation
The coordinate transformation technique is applied to the design of perfect
lenses and superlenses. In particular, anisotropic metamaterials that magnify
two-dimensional planar images beyond the diffraction limit are designed by the
use of oblate spheroidal coordinates. The oblate spheroidal perfect lens or
superlens can naturally be used in reverse for lithography of planar
subwavelength patterns.Comment: 8 pages, 8 figures, v2: submitted, v3: accepted by Physical Review
An ultracold low emittance electron source
Ultracold atom-based electron sources have recently been proposed as an
alternative to the conventional photo-injectors or thermionic electron guns
widely used in modern particle accelerators. The advantages of ultracold
atom-based electron sources lie in the fact that the electrons extracted from
the plasma (created from near threshold photo-ionization of ultracold atoms)
have a very low temperature, i.e. down to tens of Kelvin. Extraction of these
electrons has the potential for producing very low emittance electron bunches.
These features are crucial for the next generation of particle accelerators,
including free electron lasers, plasma-based accelerators and future linear
colliders. The source also has many potential direct applications, including
ultrafast electron diffraction (UED) and electron microscopy, due to its
intrinsically high coherence. In this paper, the basic mechanism of ultracold
electron beam production is discussed and our new research facility for an
ultracold, low emittance electron source is introduced. This source is based on
a novel alternating current Magneto-Optical Trap (the AC-MOT). Detailed
simulations for a proposed extraction system have shown that for a 1 pC bunch
charge, a beam emittance of 0.35 mm mrad is obtainable, with a bunch length of
3 mm and energy spread 1 %.Comment: 15 pages, 9 figures, to be published in Journal of Instrumentation in
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Ampelisca lusitanica (Crustacea: Amphipoda): new species for the Atlantic coast of Morocco
Background
This study reports for the first time the presence of the Lusitanian ampeliscid amphipod Ampelisca lusitanica Bellan-Santini & Marques, 1986 in the northwestern Atlantic coast of Morocco.
Methods
Specimens were collected in January 2015 from intertidal rock pools along the El Jadida shoreline associated with the brown algae Bifurcaria bifurcata and Sargassum muticum.
Results
Systematic description of the species is presented, as well as a discussion of its ecological and geographical distribution.
Conclusion
This new finding extends the geographical distribution from the Lusitanian (Europe) to the Mauritanian (Africa) region and increases knowledge of the ecology and the global distribution of A. lusitanica found, previously, only on Portuguese and Spanish coasts.info:eu-repo/semantics/publishedVersio
Conservation of canonical circulation and its relation to finite Hall term magnetohydrodynamics
Real-time phase-selective data acquisition system for measurement of wave phenomena in pulsed plasma discharges
Burkitt lymphoma beyond MYC translocation: N-MYC and DNA methyltransferases dysregulation
Background: The oncogenic transcription factor MYC is pathologically activated in many human malignancies. A paradigm for MYC dysregulation is offered by Burkitt lymphoma, where chromosomal translocations leading to Immunoglobulin gene-MYC fusion are the crucial initiating oncogenic events. However, Burkitt lymphoma cases with no detectable MYC rearrangement but maintaining MYC expression have been identified and alternative mechanisms can be involved in MYC dysregulation in these cases. Methods: We studied the microRNA profile of MYC translocation-positive and MYC translocation-negative Burkitt lymphoma cases in order to uncover possible differences at the molecular level. Data was validated at the mRNA and protein level by quantitative Real-Time polymerase chain reaction and immunohistochemistry, respectively. Results: We identified four microRNAs differentially expressed between the two groups. The impact of these microRNAs on the expression of selected genes was then investigated. Interestingly, in MYC translocation-negative cases we found over-expression of DNA-methyl transferase family members, consistent to hypo-expression of the hsa-miR-29 family. This finding suggests an alternative way for the activation of lymphomagenesis in these cases, based on global changes in methylation landscape, aberrant DNA hypermethylation, lack of epigenetic control on transcription of targeted genes, and increase of genomic instability. In addition, we observed an over-expression of another MYC family gene member, MYCN that may therefore represent a cooperating mechanism of MYC in driving the malignant transformation in those cases lacking an identifiable MYC translocation but expressing the gene at the mRNA and protein levels. Conclusions: Collectively, our results showed that MYC translocation-positive and MYC translocation-negative Burkitt lymphoma cases are slightly different in terms of microRNA and gene expression. MYC translocation-negative Burkitt lymphoma, similarly to other aggressive B-cell non Hodgkin's lymphomas, may represent a model to understand the intricate molecular pathway responsible for MYC dysregulation in cancer
Combined searches for the production of supersymmetric top quark partners in protonâproton collisions at âs=13Te
Search for a heavy Higgs boson decaying into two lighter Higgs bosons in the ÏÏbb final state at 13 TeV
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