71 research outputs found
2-Hydroxymethyl-1,3-dimethylimidazolium iodide
The crystal packing of the title compound, C6H11N2O+·I−, can be described as intercalated layers lying parallel to (010), with the iodide ions located between the cations. A weak intramolecular C—H⋯O hydrogen bond occurs within the cation. In the crystal, intermolecular O—H⋯I hydrogen bonds result in the formation of a three-dimensional network and reinforce the cohesion of the ionic structure
2-Chloroquinoline-3-carboxylic acid
The crystal structure of the title compound, C10H6ClNO2, can be described by two types of crossed layers which are parallel to (110) and (10). The crystal packing is stabilized by intermolecular C—H⋯O and O—H⋯N hydrogen bonds, resulting in the formation of a two-dimensional network and reinforcing the cohesion of the structure
rac-2-(2-Chloro-6-methylquinolin-3-yl)-2,3-dihydroquinolin-4(1H)-one
In the title compound, C19H15ClN2O, the quinoline ring forms a dihedral angle of 43.24 (1)° with the benzene ring of the dihydroquinolinyl system. In the crystal, molecules are linked through a single weak C—H⋯O hydrogen bond, forming ribbons which extend along (100), giving alternating zigzag molecular layers which stack down the b-axis direction
2-(2-Chloro-6,7-dimethylquinolin-3-yl)-2,3-dihydroquinolin-4(1H)-one
In the title molecule, C20H17ClN2O, the dihedral angle between the mean plane of the quinoline ring system and the benzene ring of the dihydroquinolinone moiety is 57.84 (8)°. In the crystal, molecules are linked into centrosymmetric dimers via pairs of intermolecular N—H⋯N hydrogen bonds. These dimers are further stabilized by weak π–π stacking interactions between pyridine rings with a centroid–centroid distance of 3.9414 (12) Å
2-Chloro-3-[(E)-(hydrazin-1-ylidene)methyl]-6-methoxyquinoline
In the title compound, C11H10ClN3O, the quinoline ring system is essentially planar, the r.m.s. deviation for the non-H atoms being 0.014 (2) Å with a maximum deviation from the mean plane of 0.0206 (14) Å for the C atom bonded to the –CH—N=NH2 group. In the crystal, molecules are linked via N—H⋯O and N—H⋯N hydrogen bonds, forming zigzag layers parallel to (010)
Synthesis of Some New 3-Pyrrolidinylquinoline Derivatives via 1,3-Dipolar Cycloaddition of Stabilized Azomethine Ylides to Quinolinyl α,β- Unsaturated Ketones
International audienceN-Metallated azomethine ylide generated from methyl (E)-N-benzylideneglycinate, LiBr and triethylamine underwent cycloaddition to quinolyl α,β- unsaturated ketones with excellent diastereoselectivity to afford new functionalised 3-pyrrolidinylquinoline derivatives
5,8-Dimethoxy-2-phenyl-1,4-dihydroquinoline-3-carbonitrile
The crystal structure of the title molecule, C18H16N2O2, can be described as two types of crossed layers parallel to the (110) and (10) planes. An intramolecular N—H⋯O hydrogen bond occurs
(3RS,4SR)-Methyl 4-(2-chloro-5,8-dimethoxyquinolin-3-yl)-1-phenylpyrrolidine-3-carboxylate
The molecule of the title compound, C23H23ClN2O4, contains a quinolyl unit linked to a functionalized pyrrolidine system with a 3,4-trans arrangement of the substituents. The unit cell contains two stereoisomers that have the absolute stereochemistry 3S,4R and 3R,4S. The pyrrolidine ring adopts a twist conformation with pseudo-rotation parameters P = 258.2 (3)° and τ(M) = 35.3 (1)°. The packing is stabilized by C—H⋯π interactions and offset π–π stacking (centroid-to-centroid distance = 3.849 Å, interplanar distance = 3.293 Å and slippage = 1.994 Å) between phenyl rings, leading to a two-dimensional network
Ethyl 4-(2-chloroquinolin-3-yl)-1-phenyl-1H-pyrrole-3-carboxylate
In the molecule of the title compound, C22H17ClN2O2, the dihedral angles formed by the pyrrole ring with the quinoline and phenyl rings are 67.93 (8) and 28.40 (11)°, respectively. In the crystal structure, molecules are linked into dimers by intermolecular C—H⋯O hydrogen bonds
4,5-Dibromo-1,2-dimethyl-1H-imidazol-3-ium bromide
In the title salt, C5H7Br2N2
+·Br−, the cation and anion are connected by an N—H⋯Br hydrogen bond. In the crystal, there are intercalated layers parallel to (10-2) in which bromide ions are located between the cations. Weak intermolecular C—H⋯Br hydrogen bonds are also observed
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