298 research outputs found

    Особенности инвестирования в человеческий капитал

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    Article about the features of investment in human capital. Explore different areas of investment in human capital, and also addresses the problems associated with investing in human capital and ways to solve them. The author proves the thesis futile investment in human capital and labor without the efforts of the media. This article attempts to prove a similar investment in human and physical capital

    Theoretical Investigation of Phase Transitions of Graphite and Cubic 3C Diamond Into Hexagonal 2H Diamond Under High Pressures

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    Possible techniques for experimentally obtaining hexagonal diamond are studied in the scope of the density functional theory method. It has been found that hexagonal diamond may be created as a result of structural transition at 61 68 GPa uniaxial compression from orthorhombic AB graphite and at 57 66GPa from hexagonal AA graphite. Also the formation of hexagonal diamond is shown to take place in case of very strong 300 380 GPa compression of cubic diamond. X ray and electron microscopic data on nanodiamonds from meteorite craters are analyzed for the presence of hexagonal diamond. The analysis shows that impact origin carbon materials do not contain pure cubic and hexagonal diamonds, and the layers of nascent crystals of diamond polytypes are randomly packe

    In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

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    The use of Micro-Computed Tomography (MicroCT) for in vivo studies of small animals as models of human disease has risen tremendously due to the fact that MicroCT provides quantitative high-resolution three-dimensional (3D) anatomical data non-destructively and longitudinally. Most importantly, with the development of a novel preclinical iodinated contrast agent called eXIA160, functional and metabolic assessment of the heart became possible. However, prior to the advent of commercial MicroCT scanners equipped with X-ray flat-panel detector technology and easy-to-use cardio-respiratory gating, preclinical studies of cardiovascular disease (CVD) in small animals required a MicroCT technologist with advanced skills, and thus were impractical for widespread implementation. The goal of this work is to provide a practical guide to the use of the high-speed Quantum FX MicroCT system for comprehensive determination of myocardial global and regional function along with assessment of myocardial perfusion, metabolism and viability in healthy mice and in a cardiac ischemia mouse model induced by permanent occlusion of the left anterior descending coronary artery (LAD)

    Experience at Russian State Agrarian University – Moscow Timiryazev Agricultural Academy on introduction and integration of precision agriculture technology

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    Traditional and precision agriculture technologies are compared on the basis of the field experiment. Problems of soil and crop survey and mapping are discussed

    The Wellesley News (06-10-1957)

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    https://repository.wellesley.edu/wcnews/1157/thumbnail.jp

    Prognostic value of vascular remodeling parameters in the development of adverse cardiovascular events in patients with gastric cancer

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    Aim. To determine a possible prognostic marker for adverse cardiovascular events in patients with gastric cancer by studying the early and long-term effects of multiagent chemotherapy (MAC) on the structural and functional vascular wall parameters.Material and methods. The study included 25 patients with newly diagnosed gastric cancer who received courses of chemotherapy with platinum-based agents and fluoropyrimidines. All patients before, immediately after MAC courses and in the long-term period underwent a non-invasive assessment of vascular wall and endothelial function (photoplethysmography (PPG)). In the survivors’ cohort, a correlation analysis was performed to assess the risk of future cardiovascular events depending on changes of PPG parameters.Results. Before the MAC courses, cancer patients had endothelial dysfunction (mean occlusion index, 1,7 (1,4; 1,9), N>1,8) and structural vascular wall disorders (mean stiffness index, 8,9 m/s (7,7; 9,7), N<8 m/s, mean reflection index, 32,4% (27,5; 37,7), N<30%). All indicators significantly worsened after MAC in the form of endothelial dysfunction progression and vascular remodeling: mean occlusion index, 1,3 (1,2; 1,5) (p<0,0002), stiffness index, 10,3 m/s (9,5; 11,2) (p<0,0001), reflection index, 40,2% (35,5; 43,6) (p<0,001). Long-term follow-up averaged 2,9 years (2,3-3,7 years). All-cause and cardiovascular mortality was 32% and 12%, respectively. Nine patients developed a cardiovascular events (CVEs) (de novo, progression of prior CVD). Significant changes of vascular indicators in the long-term period was not revealed. A trend towards association between increased reflection index and a higher probability of cardiovascular pathology was revealed (OR 1,20, 95% CI 1,01-1,55, p=0,081).Conclusion. In this study, for the first time, a comprehensive assessment of the effect of MAC on endothelial dysfunction and vascular stiffness, including, in the long-term follow-up period, was carried out in patients with gastric cancer. A significant aggravation of all parameters of vascular remodeling immediately after treatment in the absence of their significant dynamics in the future has been proven. A possible prognostic marker, namely the reflection index, of an unfavorable cardiac outcome in patients with gastric cancer has been identified, which requires further study

    Russian guidelines for sudden cardiac death risk assessment and prevention (second edition) – 2018. Pocket version

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    cardiovascular diseases, sudden cardiac death, risk, treatment, preventionCardiovascular mortality in Russia is one of the highest in the world reaching 614 deaths per 100,000 annually. The main causes of death from cardiovascular diseases are the progression of congestive heart failure (about half of all cases) and sudden cardiac death (the other half). Thus, we can assume that the incidence of sudden cardiac death in 2016 was no less than 300,000. In the abbreviated version of the National Recommendations in English, the principles of decision-making algorithms in various clinical situations are used
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