27 research outputs found
Chemoselective Construction of Substituted Conjugated Dienes Using an Olefin Cross-Metathesis Protocol
Full text linkMetathesis of Electron-Rich Olefins: Structure and Reactivity of Electron-Rich Carbene Complexes
Full text linkCatalytic dehalogenation of aryl chlorides mediated by ruthenium(II) phosphine complexes
Get PDFThe catalytic dechlorination of aryl chlorides performed by RuHCl(H_2)_2(PCy_3)_2 and RuH_2(H_2)_2(PCy_3)_2 in alcohols is rapid and complete within 1 h. The mechanism involves a transfer hydrogenation step with participation of the alcohol. The system exhibits significant functional group tolerance. The catalyst can be generated in situ from [RuCl_2(COD)]_x (COD = cyclooctadiene) and 2 equiv of phosphine (PCy_3 or P^iPr_3). Catalytic conversions are similar to those observed when an isolated precatalyst is used. Mechanistic considerations and the scope of the process are discussed
Olefin Cross-Metathesis as a Tool in Natural Product Degradation. The Stereochemistry of (+)-Falcarindiol
No full text
