Polystyrene-based nanocomposites with different fillers: fabrication and mechanical properties

The paper presents a comprehensive analysis of elastic properties of polystyrene-based nanocomposites filled with different types of inclusions: small spherical particles (SiO2 and Al2O3), alumosilicates (montmorillonite, halloysite natural tubules and Mica) and carbon nanofillers (carbon black and multi-walled carbon nanotubes). Composites were fabricated by melt technology. The analysis of composite melts showed that the introduction of Montmorillonite, Multi-walled carbon nanotubes, and Al2O3 particles provided an increase in melt viscosity by an average of 2 to 5 orders of magnitude over the pure polystyrene. Block samples of composites with different filler concentrations were prepared, and their linear and nonlinear elastic properties were studied. The introduction of more rigid particles led to a more profound increase in the elastic modulus of the composite, with the highest rise of about 80% obtained with carbon fillers. Carbon black particles provided also an enhanced strength at break of about 20% higher than that of pure polystyrene. The nonlinear elastic moduli of composites were shown to be more sensitive to addition of filler particles to the polymer matrix than the linear ones. The nonlinearity coefficient $\beta$ comprising the combination of linear and nonlinear elastic moduli of a material demonstrated considerable changes correlating with changes of the Young's modulus. The absolute value of $\beta$ showed rise in 1.5-1.6 times in the CB- and HNT-containing composites as compared to that of pure PS. The changes in nonlinear elasticity of fabricated composites were compared with measurements of the parameters of bulk nonlinear strain waves in them. Variations of wave velocity and decay decrement correlated with observed enhancement of materials nonlinearity

Effectiveness of medicinal treatment of endometriosis

Endometriosis is a process in which benign tissue growth occurs outside the uterine cavity, according to the morphological and functional properties of a similar endometrium. It is difficult to manage patients with endometriosis, since they have a variable clinical picture and the severity of the course of the disease. The management tactics of such patients depend on the age of the patients, the form / stage of the disease, the nature of the symptoms, reproductive tasks, as well as the risks, side effects and economic cost-effectiveness of treatment. In a number of cases, endometriosis is considered as a chronic recurrent disease requiring constant attention and treatment. This paper discusses the conservative treatment of patients with endometriosis and the effectiveness of hormone therapy.Эндометриоз – процесс, при котором за пределами полости матки происходит доброкачественное разрастание ткани, по морфологическим и функциональным свойствам подобной эндометрию. Вести больных эндометриозом сложно, так как они имеют вариабельную клиническую картину и тяжесть течения заболевания. Тактика ведения таких пациенток зависит от возраста пациенток, формы/стадии заболевания, характера симптомов, репродуктивных задач, а также от рисков, побочных эффектов и экономической рентабельности лечения. В ряде случаев эндометриоз рассматривают как хроническое рецидивирующее заболевание, требующее постоянного внимания и лечения. В данной работе рассмотрено консервативное лечение пациенток с эндометриозом и эффективность гормональной терапии

Assessment of palliative health care in Orenburg

Palliative care (PMP) is a set of medical interventions aimed at relieving pain and alleviating other severe manifestations of the disease, in order to improve the quality of life of terminally ill citizens. Worldwide, only about 14% of people in need of palliative care receive it today. Currently, palliative care has begun to actively develop; in February 2019, in addition to palliative departments, a patronage service has opened in Orenburg. This study presents the work of the palliative departments and patronage services for 2019.Паллиативная медицинская помощь (ПМП) представляет собой комплекс медицинских вмешательств, направленных на избавление от боли и облегчение других тяжелых проявлений заболевания, в целях улучшения качества жизни неизлечимо больных граждан. Во всем мире паллиативную медицинскую помощь получают сегодня лишь около 14% людей, нуждающихся в ней. В настоящее время паллиативная помощь стала активно развиваться, в городе Оренбург помимо паллиативных отделений в феврале 2019 года открылась патронажная служба. В данном исследовании представлена работа паллиативных отделений и патронажной службы за 2019 год

Effectiveness of medicinal treatment of endometriosis

Endometriosis is a process in which benign tissue growth occurs outside the uterine cavity, according to the morphological and functional properties of a similar endometrium. It is difficult to manage patients with endometriosis, since they have a variable clinical picture and the severity of the course of the disease. The management tactics of such patients depend on the age of the patients, the form / stage of the disease, the nature of the symptoms, reproductive tasks, as well as the risks, side effects and economic cost-effectiveness of treatment. In a number of cases, endometriosis is considered as a chronic recurrent disease requiring constant attention and treatment. This paper discusses the conservative treatment of patients with endometriosis and the effectiveness of hormone therapy.Эндометриоз – процесс, при котором за пределами полости матки происходит доброкачественное разрастание ткани, по морфологическим и функциональным свойствам подобной эндометрию. Вести больных эндометриозом сложно, так как они имеют вариабельную клиническую картину и тяжесть течения заболевания. Тактика ведения таких пациенток зависит от возраста пациенток, формы/стадии заболевания, характера симптомов, репродуктивных задач, а также от рисков, побочных эффектов и экономической рентабельности лечения. В ряде случаев эндометриоз рассматривают как хроническое рецидивирующее заболевание, требующее постоянного внимания и лечения. В данной работе рассмотрено консервативное лечение пациенток с эндометриозом и эффективность гормональной терапии

Visualization 1: Digital holographic microscopy in label-free analysis of cultured cells’ response to photodynamic treatment

Visualization 1 presents the alteration dynamics in HeLa cells induced by 7-min irradiation and recorded in both optical and holographic microscopes. Originally published in Optics Letters on 01 November 2016 (ol-41-21-5035