Profitability and risk evaluation of novel perennial pasture systems for livestock producers in the high rainfall zone: Context, Approach and Preliminary Results

The decision to invest in pasture improvement raises various questions for the livestock grazier, with the most pertinent being about the potential returns and risks. In the high rainfall zone of south-west Victoria, researchers have trialled novel perennial pasture systems with the aim of substantially increasing on-farm profits whilst simultaneously improving environmental outcomes. Results from the Hamilton EverGraze® proof site have shown potential to greatly improve livestock production. Promotion of the pasture technology is the next step. Key to this process is developing information about profitability and risk regarding the decision to invest in the new pasture. To help meet this need a model of a representative mixed livestock farm system for the region has been developed to generate information about profit, cash wealth and risk to aid extension and help inform decisions. The farm is comprised of a wool and meat producing sheep system and a beef enterprise. Using the model, the performance of two of the novel pasture systems can be evaluated against current practice, and compared to determine which of the two is the most beneficial EverGraze® option for the future. The risk associated with the pasture decision is assessed by considering different price structures and seasonal outcomes, and evaluating these effects on net benefits. Discounted cash flows, net present values and internal rates of return are estimated for the alternative systems, which include the effects of this price and seasonal variability. Preliminary results have been calculated, however further work is needed to confirm these. The method and results of the analysis provide information that is valuable for farm decisions about investing in a new pasture system and provide a basis for future economic analyses at the case study site and elsewhere.Farm Management,

A Helminth Protease Inhibitor Modulates the Lipopolysaccharide-Induced Proinflammatory Phenotype of Microglia in vitro

Objective: The aim of this study was to examine whether the natural protease inhibitor Av-cystatin (rAv17) of the parasitic nematode Acanthocheilonema viteae exerts anti-inflammatory effects in an in vitro model of lipopolysaccharide (LPS)-activated microglia. Methods: Primary microglia were harvested from the brains of 2-day-old Wistar rats and cultured with or without rAv17 (250 nM). After 6 and 24 h the release of nitric oxide (Griess reagent) and TNF-α (ELISA) was measured in the supernatant. Real-time PCR was performed after 2, 6 and 24 h of culture to measure the mRNA expression of IL-1β, IL-6, TNF-α, COX-2, iNOS and IL-10. To address the involved signaling pathways, nuclear NF-ĸB translocation was visualized by immunocytochemistry. Morphological changes of microglia were analyzed by Coomassie blue staining. Differences between groups were calculated using one-way ANOVA with Bonferroni's post hoc test. Results: Morphological analysis indicated that LPS-induced microglial transformation towards an amoeboid morphology is inhibited by rAv17. Av-cystatin caused a time-dependent downregulation of proinflammatory cytokines, iNOS and COX-2 mRNA expression, respectively. This was paralleled by an upregulated expression of IL-10 in resting as well as in LPS-stimulated microglia. Av-cystatin reduced the release of NO and TNF-α in the culture supernatant. Immunocytochemical staining demonstrated an attenuated translocation of NF-ĸB by Av-cystatin in response to LPS. In addition, Western blot analysis revealed a rAv17-dependent reduction of the LPS-induced ERK1/2-pathway activation. Conclusion: The parasite-derived secretion product Av-cystatin inhibits proinflammatory mechanisms of LPS-induced microglia with IL-10, a potential key mediator.Peer Reviewe

The Role Modelling and Farming Systems Research Can Play in Redesigning Grazing Systems for Improved Productivity and Environmental Sustainability

Achieving production and natural resource outcomes from farming systems is critical with growing demand for livestock products, increasing pressure on land and water resources and the desire of farmers to improve profit and standard of living. In many countries this brings to the fore a number of policy dilemmas and conflicts in terms of pastoral household livelihood, regional economic growth and development, as well as natural resource management. By using two case studies; (1) Temperate Grasslands in Southern Australia (EverGraze project); and (2) Western Grasslands in North West China (ACIAR project), this paper considers how farming systems can be redesigned for production and environmental outcomes using modelling and farming systems research. Farming systems, as well as the regions and economies in which they operate, are complex and under constant change. The use of models combined with good science, relevant data and regional validation is essential to examine alternative systems that are better suited to changed operating conditions. Bio-economic modelling helps to understand trade-offs between production and enterprise performance and environmental sustainability over time and, most importantly, where multiple benefits from farming systems are possible. We contend that it is possible to redesign farming systems with both enterprise and environmental sustainability in mind. However the approach used to design and test alternative farming systems is important in an era of declining research resources and increasing complexity

EverGraze: A Partnership between Researchers, Farmers and Advisors to Deliver Effective Grassland Management

The profitable and sustainable management of livestock production from grassland systems is challenging and it can be difficult to develop a research structure that addresses farmer’s needs and has acceptable rigour and on-ground impact. This paper describes the attributes of research, development and extension (RD&E) programs that are required for a successful partnership between researchers, farmers and advisors. Insights are provided from the EverGraze program that designed, tested and implemented farming systems based on perennial pastures across southern Australia. With this project farmers and advisors were involved in setting research direction, designing experiments, providing strategic guidance over the management of the systems experiments and then the synthesis of regionally applicable key messages. This involvement ensured the relevance of the research and aided in the extension and uptake of the information. The result has been an effective partnership between researchers, farmers and advisors that had a high level of impact across the high rainfall zone (HRZ) of southern Australia, with 1950 farmers or ~8% of those in the HRZ documented as having changed practice over an area of 816,000 ha over a five year period (2009 to 2014)

Sheep Updates 2006 - part 3

This session covers six papers from different authors: GRAZING 1. Making better use of clover, Karen Venning and Andrew Thompson, Department of Primary Industries, Victoria 2. Grazing systems demonstration to optimise pasture utilisation and stocking rate, Mike Hyder, Sue-Ellen Shaw, Kelly Hill and Ron McTaggart, Department of Agriculture and Food Western Australia. 3. Know your audience to increase their rate of practice change - Lifetime Wool as an example, Gus Rose, Department of Agriculture and Food Western Australia, Carolyn Kabore, Kazresearch REPRODUCTION 4. Lifetime Wool - Ewe Management Guidlines, Mandy Curnow, Department of Agriculture and Food Western Australia 5. Achieving the best reproductive performance from your hoggets, Kenyon PR, Morris ST, West DM, Perkins NR, Pinchbeck GL., Institute of Veterinary, Animal and Biomedical Sciences, Massey University, New Zealand. 6. Lifetime Wool: Twin futures, Dr Ralph Behrendt, Department of Primary Industries, Victori

Sheep Updates 2008 - part 3

This session covers fiveteen papers from different authors: CONTROLLING FLY STRIKE 1. Breeding for Blowfly Resistance - Indicatoe Traits, LJE Karlsson, JC Greeff, L Slocombe, Department of Agriculture & Food, Western Australia 2.A practical method to select for breech strike resistance in non-pedigreed Merino flocks, LJE Karlsson, JC Greeff, L Slocombe, K. Jones, N. Underwood, Department of Agriculture & Food, Western Australia 3. Twice a year shearing - no mulesing, Fred Wilkinson, Producer, Brookton WA BEEF 4. Commercial testing of a new tool for prediction of fatness in beef cattle, WD HoffmanA, WA McKiernanA, VH OddyB, MJ McPheeA, Cooperative Research Centre for Beef Genetic Technologies, A N.S.W. Deptartment of Primary Industries, B University of New England 5. A new tool for the prediction of fatness in beef cattle, W.A. McKiernanA, V.H. OddyB and M.J. McPheeC; Cooperative Research Centre for Beef Genetic Technologies, A N.S.W. Dept of Primary Industries, B University of New England, C N.S.W. Dept of Primary Industries Beef Industry Centre of Excellence. 6. Effect of gene markers for tenderness on eating quality of beef, B.L. McIntyre, CRC for Beef Genetic Technologies, Department of Agriculture and Food WA 7. Accelerating beef industry innovation through Beef Profit Partnerships, Parnell PF1,2, Clark RA1,3, Timms J1,3, Griffith G1,2, Alford A1,2, Mulholland C1 and Hyland P1,4,1Co-operative Research Centre for Beef Genetic Technologies; 2NSW Department of Primary Industries; 3 Qld Department of Primary Industries and Fisheries; 4The University of Queensland. SUSTAINABILITY 8. The WA Sheep Industry - is it ethically and environmentally sustainable? Danielle England, Department of Agriculture and Food Western Australia 9. Overview of ruminant agriculture and greenhouse emissions, Fiona Jones, Department of Agriculture and Food Western Australia 10. Grazing for Nitrogen Efficiency, John Lucey, Martin Staines and Richard Morris, Department of Agriculture and Food Western Australia 11. Investigating potential adaptations to climate change for low rainfall farming system, Megan Abrahams, Caroline Peek, Dennis Van Gool, Daniel Gardiner, Kari-Lee Falconer, Department of Agriculture and Food Western Australia SHEEP 12. Benchmarking ewe productivity through on-farm genetic comparisons, Sandra Prosser, Mario D’Antuono and Johan Greeff; Department of Agriculture and Food Western Australia 13. Increasing profitability by pregnancy scanning ewes, John Young1, Andrew Thompson2 and Chris Oldham2; 1Farming Systems Analysis Service, Kojonup, WA, 2Department of Agriculture and Food Western Australia 14. Targeted treatment of worm-affected sheep - more efficient, more sustainable, Brown Besier, Department of Agriculture and Food Western Australia 15. Improving Weaner Sheep Survival, Angus Campbell and Ralph Behrendt, Cooperative Research Centre for Sheep Industry Innovatio

Lawson criterion for ignition exceeded in an inertial fusion experiment

For more than half a century, researchers around the world have been engaged in attempts to achieve fusion ignition as a proof of principle of various fusion concepts. Following the Lawson criterion, an ignited plasma is one where the fusion heating power is high enough to overcome all the physical processes that cool the fusion plasma, creating a positive thermodynamic feedback loop with rapidly increasing temperature. In inertially confined fusion, ignition is a state where the fusion plasma can begin "burn propagation" into surrounding cold fuel, enabling the possibility of high energy gain. While "scientific breakeven" (i.e., unity target gain) has not yet been achieved (here target gain is 0.72, 1.37 MJ of fusion for 1.92 MJ of laser energy), this Letter reports the first controlled fusion experiment, using laser indirect drive, on the National Ignition Facility to produce capsule gain (here 5.8) and reach ignition by nine different formulations of the Lawson criterion

Requirements to assess physical work-ability of production workers in the manufacturing industry

Musculoskeletal disorders (MSD) are a major reason for the absence due to illness of workers in the manufacturing industry. There is a need to evaluate the capabilities of workers as well as to systemize the data. With this data, on the one hand, a suitable workplace for workers with MSD’s can be developed, on the other hand, this data can be used by workplace designers to create preventive, capability-appropriate workplaces. The requirements for functional capacity evaluation in the context of the manufacturing industry are discussed as well as the benefit of such a procedure. Furthermore, the important capabilities which are relevant for assembly work and therefore need to be assessed are presented and described in detail. Derived from the description of the capabilities and guidelines for the occupational physicians, the capabilities specific to musculoskeletal complains and related functional limitations need to be assessed