Endobronchial lipoma in a patient with Churg-Strauss syndrome

Churg-Strauss syndrome (CSS) is a disorder characterized by hypereosinophilia and systemic vasculitis complicating a preexisting asthma. We report here a case of CSS with an endobronchial lesion, initially considered to be an endobronchial granuloma of CSS, which was finally diagnosed as a lipoma, a very rare benign tumor of the tracheobronchial tree. To our knowledge, this is the first case in the literature presenting with these two rare entities

Respiratory symptoms and functions in tea workers

Respiratory symptoms and function tests were studied in tea workers and in a control group. The prevalance of acute and chronic respiratory symptoms were not different in two groups except for an acute burning sensation of eye-nose-throat and a chronic cough. Also the comparison of the respiratory function tests between tea workers (both smokers and nonsmokers) and the controls were not different at preshift and postshift 30th minute and 8th hour. When preshift and postshift results were compared in tea workers ( both in smokers and nonsmokers); statistically significant reductions of FEV1, FEV1/FVC, FEF25-75 and FEF25 were seen at the postshift values. However statistically significant reductions were not observed in controls. Thus we conclude acute tea dust exposure may cause bronchial obstruction particularly in small airways

Childhood Onset Analgesic Intolerance: A Marker For Bronchial-Asthma In Adulthood?

Analgesic intolerance (AI) which is classically known as a disease of the middle-aged adults, not uncommonly starts in childhood. In this study we sought to identify the characteristics of childhood onset Al and evaluated its association with the development of asthma. Among 729 analgesic intolerant patients followed in our institution between January 1991 and July 2004, 50 (16 mate, 34 female, 6.8% of the total Al population) had history of Al starting before the age of 18. The prevalence of asthma was 24% in childhood and increased to 40% during adulthood. Atopy was more common in patients with bronchial asthma (p < 0.05). The mean (+/- SD) age of onset for asthma (18.6 +/- 9.7years) was significantly greater than the onset of both rhinitis and Al (13.0 +/- 6.5 and 13.2 +/- 4.0 years, respectively). This finding is different than the chronology of events reported in the literature for adult onset Al patients, in which rhinitis and asthma usually precede the development of Al. The presence of such a difference in the sequence of disease patterns may be a clue for the pathophysiologic differences underlying childhood and adult onset Al. The role of childhood onset Al as a risk factor for developing for asthma in adulthood should be further assessed in prospective patient cohorts. (c) 2008 Elsevier Ltd. All rights reserved