The Fractal Dimension of Projected Clouds

The interstellar medium seems to have an underlying fractal structure which can be characterized through its fractal dimension. However, interstellar clouds are observed as projected two-dimensional images, and the projection of a tri-dimensional fractal distorts its measured properties. Here we use simulated fractal clouds to study the relationship between the tri-dimensional fractal dimension (D_f) of modeled clouds and the dimension resulting from their projected images. We analyze different fractal dimension estimators: the correlation and mass dimensions of the clouds, and the perimeter-based dimension of their boundaries (D_per). We find the functional forms relating D_f with the projected fractal dimensions, as well as the dependence on the image resolution, which allow to estimatethe "real" D_f value of a cloud from its projection. The application of these results to Orion A indicates in a self-consistent way that 2.5 < D_f < 2.7 for this molecular cloud, a value higher than the result D_per+1 = 2.3 some times assumed in literature for interstellar clouds.Comment: 27 pages, 13 figures, 1 table. Accepted for publication in ApJ. Minor change

Pre-Existing Superbubbles as the Sites of Gamma-Ray Bursts

According to recent models, gamma-ray bursts apparently explode in a wide variety of ambient densities ranging from ~ 10^{-3} to 30 cm^{-3}. The lowest density environments seem, at first sight, to be incompatible with bursts in or near molecular clouds or with dense stellar winds and hence with the association of gamma-ray bursts with massive stars. We argue that low ambient density regions naturally exist in areas of active star formation as the interiors of superbubbles. The evolution of the interior bubble density as a function of time for different assumptions about the evaporative or hydrodynamical mass loading of the bubble interior is discussed. We present a number of reasons why there should exist a large range of inferred afterglow ambient densities whether gamma-ray bursts arise in massive stars or some version of compact star coalescence. We predict that many gamma-ray bursts will be identified with X-ray bright regions of galaxies, corresponding to superbubbles, rather than with blue localized regions of star formation. Massive star progenitors are expected to have their own circumstellar winds. The lack of evidence for individual stellar winds associated with the progenitor stars for the cases with afterglows in especially low density environments may imply low wind densities and hence low mass loss rates combined with high velocities. If gamma-ray bursts are associated with massive stars, this combination might be expected for compact progenitors with atmospheres dominated by carbon, oxygen or heavier elements, that is, progenitors resembling Type Ic supernovae.Comment: 14 pages, no figures, submitted to The Astrophysical Journa

Trapping of a spiral-like intermediate of the bacterial cytokinetic protein FtsZ

The earliest stage in bacterial cell division is the formation of a ring, composed of the tubulin-like protein FtsZ, at the division site. Tight spatial and temporal regulation of Z-ring formation is required to ensure that division occurs precisely at midcell between two replicated chromosomes. However, the mechanism of Z-ring formation and its regulation in vivo remain unresolved. Here we identify the defect of an interesting temperature-sensitive ftsZ mutant (ts1) of Bacillus subtilis. At the nonpermissive temperature, the mutant protein, FtsZ(Ts1), assembles into spiral-like structures between chromosomes. When shifted back down to the permissive temperature, functional Z rings form and division resumes. Our observations support a model in which Z-ring formation at the division site arises from reorganization of a long cytoskeletal spiral form of FtsZ and suggest that the FtsZ(Ts1) protein is captured as a shorter spiral-forming intermediate that is unable to complete this reorganization step. The ts1 mutant is likely to be very valuable in revealing how FtsZ assembles into a ring and how this occurs precisely at the division site. <br /

A "Kane's Dynamics" Model for the Active Rack Isolation System

In the late 1980s, microgravity researchers began to voice their concern that umbilical-transmitted energy could significantly degrade the acceleration environment of microgravity space science experiments onboard manned spacecraft. Since umbilicals are necessary for many experiments, control designers began to seek ways to compensate for these "indirect" disturbances. Hampton, et al., used the Kane s method to develop a model of the active rack isolation system (ARIS) that includes (1) actuator control forces, (2) direct disturbance forces, and (3) indirect, actuator-transmitted disturbances. Their model does not, however, include the indirect, umbilical-transmitted disturbances. Since the umbilical stiffnesses are not negligible, these indirect disturbances must be included in the model. Until the umbilicals have been appropriately included, the model will be incomplete. This Technical Memorandum presents a nonlinear model of ARIS with umbilicals included. Model verification was achieved by utilizing two commercial-off-the-shelf software tools. Various forces and moments were applied to the model to yield simulated responses of the system. Plots of the simulation results show how various critical points on an ARIS-outfitted international standard payload rack behave under the application of direct disturbances, indirect disturbances, and control forces. Simulations also show system response to a variety of initial conditions

A Test of the Standard Hypothesis for the Origin of the HI Holes in Holmberg II

The nearby irregular galaxy Holmberg II has been extensively mapped in HI using the Very Large Array (VLA), revealing intricate structure in its interstellar gas component (Puche et al. 1992). An analysis of these structures shows the neutral gas to contain a number of expanding HI holes. The formation of the HI holes has been attributed to multiple supernova events occurring within wind-blown shells around young, massive star clusters, with as many as 10-200 supernovae required to produce many of the holes. From the sizes and expansion velocities of the holes, Puche et al. assigned ages of ~10^7 to 10^8 years. If the supernova scenario for the formation of the HI holes is correct, it implies the existence of star clusters with a substantial population of late-B, A and F main sequence stars at the centers of the holes. Many of these clusters should be detectable in deep ground-based CCD images of the galaxy. In order to test the supernova hypothesis for the formation of the HI holes, we have obtained and analyzed deep broad-band BVR and narrow-band H-alpha images of Ho II. We compare the optical and HI data and search for evidence of the expected star clusters in and around the HI holes. We also use the HI data to constrain models of the expected remnant stellar population. We show that in several of the holes the observed upper limits for the remnant cluster brightness are strongly inconsistent with the SNe hypothesis described in Puche et al. Moreover, many of the HI holes are located in regions of very low optical surface brightness which show no indication of recent star formation. Here we present our findings and explore possible alternative explanations for the existence of the HI holes in Ho II, including the suggestion that some of the holes were produced by Gamma-ray burst events.Comment: 30 pages, including 6 tables and 3 images. To appear in Astron. Journal (June 1999

A Fractal Analysis of the HI Emission from the Large Magellanic Cloud

A composite map of HI in the LMC using the ATCA interferometer and the Parkes multibeam telescope was analyzed in several ways in an attempt to characterize the structure of the neutral gas and to find an origin for it. Fourier transform power spectra in 1D, 2D, and in the azimuthal direction were found to be approximate power laws over 2 decades in length. Delta-variance methods also showed the same power-law structure. Detailed models of these data were made using line-of-sight integrals over fractals that are analogous to those generated by simulations of turbulence with and without phase transitions. The results suggested a way to measure directly for the first time the line-of-sight thickness of the cool component of the HI disk of a nearly face-on galaxy. The signature of this thickness was found to be present in all of the measured power spectra. The character of the HI structure in the LMC was also viewed by comparing positive and negative images of the integrated emission. The geometric structure of the high-emission regions was found to be filamentary, whereas the geometric structure of the low-emission (intercloud) regions was found to be patchy and round. This result suggests that compressive events formed the high-emission regions, and expansion events, whether from explosions or turbulence, formed the low-emission regions. The character of the structure was also investigated as a function of scale using unsharp masks. All of these results suggest that most of the ISM in the LMC is fractal, presumably the result of pervasive turbulence, self-gravity, and self-similar stirring.Comment: 30 pages, 21 figures, scheduled for ApJ Vol 548n1, Feb 10, 200

Ectopic expression of Thy-1 in the kidneys of transgenic mice induces functional and proliferative abnormalities.

Hybrid human--mouse Thy-1.1 genes were injected into pronuclei of Thy-1.2 mice to produce transgenic animals. A hybrid gene composed of the 5' part of the mouse Thy-1.1 gene combined with the 3' human untranslated regions was expressed abnormally in the kidney podocytes, which resulted in severe protein-uria and subsequent death in several founder mice. A hybrid Thy-1 gene composed of the human coding region with the 5' and 3' flanking regions of the mouse gene was expressed abnormally in a different part of the kidney (the tubular epithelia), which resulted in a proliferative kidney disorder. In addition, a neoplasm was found in the brain of one of these mice. These results show that the Thy-1 protein can play an important role in the activation, proliferation, and differentiation of many different cell types

Modeling a high mass turn down in the stellar initial mass function

Statistical sampling from the stellar initial mass function (IMF) for all star-forming regions in the Galaxy would lead to the prediction of ~1000 Msun stars unless there is a rapid turn-down in the IMF beyond several hundred solar masses. Such a turndown is not necessary for dense clusters because the number of stars sampled is always too small. Here we explore several mechanisms for an upper mass cutoff, including an exponential decline of the star formation probability after a turbulent crossing time. The results are in good agreement with the observed IMF over the entire stellar mass range, and they give a gradual turn down compared to the Salpeter function above ~100 Msun for normal thermal Jeans mass, M_J. The upper mass turn down should scale with M_J in different environments. A problem with the models is that they cannot give both the observed power-law IMF out to the high-mass sampling limit in dense clusters, as well as the observed lack of supermassive stars in whole galaxy disks. Either there is a sharper upper-mass cutoff in the IMF, perhaps from self-limitation, or the IMF is different for dense clusters than for the majority of star formation that occurs at lower density. Dense clusters seem to have an overabundance of massive stars relative to the average IMF in a galaxy.Comment: 19 pages, 2 figures, Astrophysical Journal, Vol 539, August 10, 200

Selenium digestibility and bioactivity in dogs : what the can can, the kibble can't

There is a growing concern for the long-term health effects of selenium (Se) over-or underfeeding. The efficiency of utilization of dietary Se is subject to many factors. Our study in dogs evaluated the effect of diet type (canned versus kibble) and dietary protein concentration on Se digestibility and bioactivity. Canned and kibble diets are commonly used formats of dog food, widely ranging in protein concentration. Twenty-four Labrador retrievers were used and four canned and four kibble diets were selected with crude protein concentrations ranging from 10.1 to 27.5 g/MJ. Crude protein concentration had no influence on the digestibility of Se in either canned or kibble diets, but a lower Se digestibility was observed in canned compared to kibble diets. However, the biological activity of Se, as measured by whole blood glutathione peroxidase, was higher in dogs fed the canned diets than in dogs fed the kibble diets and decreased with increasing crude protein intake. These results indicate that selenium recommendations in dog foods need to take diet type into account